• Exposure to Antibacterial Chemicals Is Associated With Altered Composition of Oral Microbiome 

      Vindenes, Hilde Kristin; Lin, Huang; Shigdel, Rajesh; Ringel-Kulka, Tamar; Real, Francisco Gomez; Svanes, Cecilie; Peddada, Shyamal D.; Bertelsen, Randi Jacobsen (Journal article; Peer reviewed, 2022)
      Antimicrobial chemicals are used as preservatives in cosmetics, pharmaceuticals, and food to prevent the growth of bacteria and fungi in the products. Unintentional exposure in humans to such chemicals is well documented, ...
    • Exposure to environmental phenols and parabens, and relation to body mass index, eczema and respiratory outcomes in the Norwegian RHINESSA study 

      Vindenes, Hilde Kristin; Svanes, Cecilie; Lygre, Stein Håkon Låstad; Real, Francisco Gomez; Ringel-Kulka, Tamar; Bertelsen, Randi Jacobsen (Journal article; Peer reviewed, 2021)
      Background Many phenols and parabens are applied in cosmetics, pharmaceuticals and food, to prevent growth of bacteria and fungi. Whether these chemicals affect inflammatory diseases like allergies and overweight is largely ...
    • Exposures during the prepuberty period and future offspring's health: evidence from human cohort studies 

      Svanes, Cecilie; Bertelsen, Randi Jacobsen; Accordini, Simone; Holloway, John W.; Juliusson, Pétur Benedikt; Boateng, Eistine; Krauss-Etchmann, Susanne; Schlünssen, Vivi; Real, Francisco Gomez; Skulstad, Svein Magne (Journal article; Peer reviewed, 2021)
      Emerging evidence suggests that exposures in prepuberty, particularly in fathers-to-be, may impact the phenotype of future offspring. Analyses of the RHINESSA cohort find that offspring of father’s exposed to tobacco smoking ...
    • Fathers’ preconception smoking and offspring DNA methylation 

      Kitaba, Negusse Tadesse; Knudsen, Gerd Toril Mørkve; Johannessen, Ane; Rezwan, Faisal I.; Malinovschi, Andrei; Oudin, Anna; Benediktsdottir, Bryndis; Martino, David; González, Francisco Javier Callejas; Gómez, Leopoldo Palacios; Holm, Mathias; Jögi, Nils Oskar; Dharmage, Shyamali C.; Skulstad, Svein Magne; Watkins, Sarah H.; Suderman, Matthew; Gomez Real, Francisco; Schlünssen, Vivi; Svanes, Cecilie; Holloway, John W. (Journal article; Peer reviewed, 2023)
      Background Experimental studies suggest that exposures may impact respiratory health across generations via epigenetic changes transmitted specifically through male germ cells. Studies in humans are, however, limited. ...
    • Health-related quality of life as associated with asthma control, psychological status and insomnia 

      Rask-Andersen, Anna; Leander, Mai; Sundbom, Fredrik; Lampa, Erik; Oudin, Anna; Leynaert, Bénédicte; Svanes, Cecilie; Gislason, Thorarinn; Torén, Kjell; Janson, Christer (Journal article; Peer reviewed, 2022)
      Background: Asthma is associated not only with lower health-related quality of life (HRQL) but also with psychological health and insomnia. The aim of this study was to investigate associations between HRQL, asthma symptoms, ...
    • Incidence trends of airflow obstruction among European adults without asthma: a 20-year cohort study 

      Accordini, Simone; Calciano, Lucia; Marcon, Alessandro; Pesce, Giancarlo; Antó, Josep M.; Beckmeyer-Borowko, Anna B.; Carsin, Anne-Elie; Corsico, Angelo G.; Imboden, Medea; Janson, Christer; Keidel, Dirk; Locatelli, Francesca; Svanes, Cecilie; Burney, Peter G.J.; Jarvis, Deborah L.; Probst-Hensch, Nicole M.; Minelli, Cosetta (Journal article; Peer reviewed, 2020)
      Investigating COPD trends may help healthcare providers to forecast future disease burden. We estimated sex- and smoking-specific incidence trends of pre-bronchodilator airflow obstruction (AO) among adults without asthma ...
    • Indoor Airborne Microbiome and Endotoxin: Meteorological Events and Occupant Characteristics Are Important Determinants 

      Abouelhana, Hesham Amin Mohamed; Šantl-Temkiv, Tina; Cramer, Christine; Finster, Kai; Gomez Real, Francisco; Gislason, Thorarinn; Holm, Mathias; Janson, Christer; Jögi, Nils Oskar; Jogi, Rain; Malinovschi, Andrei; Marshall, Ian P. G.; Modig, Lars; Norbäck, Dan; Shigdel, Rajesh; Sigsgaard, Torben; Svanes, Cecilie; Thorarinsdottir, Hulda; Wouters, Inge M.; Schlünssen, Vivi; Bertelsen, Randi Jacobsen (Journal article; Peer reviewed, 2023)
      Airborne bacteria and endotoxin may affect asthma and allergies. However, there is limited understanding of the environmental determinants that influence them. This study investigated the airborne microbiomes in the homes ...
    • Inflammatory bowel disease and asthma. Results from the RHINE study 

      Kisiel, Marta A.; Sedvall, Martin; Malinovschi, Andrei; Franklin, Karl A.; Gislason, Thorarinn; Shlunssen, Vivi; Johansson, Ane; Modig, Lars; Jogi, Rain; Holm, Mathias; Svanes, Cecilie; Lindholdt, Louise; Carlson, Marie; Janson, Christer (Journal article; Peer reviewed, 2023)
      Background Asthma and inflammatory bowel disease (IBD) are common inflammatory diseases. The aim of this study was to investigate the associations of IBD with asthma and respiratory symptoms. Methods This study is ...
    • Influence of farm environment on asthma during the life course: A population-based birth cohort study in northern Finland 

      Kantomaa, Marko T.; Tolvanen, Mimmi; Halonen, Miia; Svanes, Cecilie; Järvelin, Marjo-Riitta; Sebert, Sylvain (Journal article; Peer reviewed, 2023)
      We investigated the influence of a farming environment on asthma at three time points from birth to 46 years using the Northern Finland Birth Cohort 1966 (n = 10,926). The prevalence of asthma was investigated by postal ...
    • Is atopic sensitization associated with indicators of early vascular ageing in adolescents? 

      Königstein, Karsten; Infanger, Denis; Bertelsen, Randi Jacobsen; Johannessen, Ane; Waje-Andreassen, Ulrike; Schmidt-Trucksäss, Arno; Svanes, Cecilie; Dratva, Julia (Peer reviewed; Journal article, 2019)
      Background: Chronic systemic inflammation accelerates early vascular ageing. Atopic sensitization and allergic diseases may involve increased inflammatory activity. This study aimed to assess whether atopic sensitization ...
    • Latitude, Birth Date, and Allergy 

      Wjst, Matthias; Dharmage, Shyamali; André, Elisabeth; Norbäck, Dan; Raherison, Chantal; Villani, Simona; Manfreda, Jure; Sunyer, Jordi; Jarvis, Deborah; Burney, Peter; Svanes, Cecilie (PLoS Medicine 2(10): e294, Peer reviewed; Journal article, 2005-10-04)
      Background: The space and time distribution of risk factors for allergic diseases may provide insights into disease mechanisms. Allergy is believed to vary by month of birth, but multinational studies taking into account ...
    • Lifelong exposure to air pollution and greenness in relation to asthma, rhinitis and lung function in adulthood 

      Kuiper, Ingrid Nordeide; Svanes, Cecilie; Markevych, Iana; Accordini, Simone; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Christensen, Jesper Heile; Forsberg, Bertil; Halvorsen, Thomas; Heinrich, Joachim; Hertel, Ole; Hoek, Gerard; Holm, Mathias; De Hoogh, Kees; Janson, Christer; Malinovschi, Andrei; Marcon, Alessandro; Nilsen, Roy Miodini; Sigsgaard, Torben; Johannessen, Ane (Journal article; Peer reviewed, 2021)
      Objectives To investigate if air pollution and greenness exposure from birth till adulthood affects adult asthma, rhinitis and lung function. Methods: We analysed data from 3428 participants (mean age 28) in the RHINESSA ...
    • Longterm follow-up in European respiratory health studies - patterns and implications 

      Johannessen, Ane; Verlato, Guiseppe; Benediktsdottir, Bryndis; Forsberg, Bertil; Franklin, Karl; Gíslason, Thorainn; Holm, Mathias; Janson, Christer; Jögi, Rain; Lindberg, Eva; Macsali, Ferenc; Omenaas, Ernst; Gomez Real, Francisco; Saure, Eirunn Waatevik; Schlünssen, Vivi; Sigsgaard, Torben; Skorge, Trude Duelien; Svanes, Cecilie; Torén, Kjell; Waatevik, Marie Johanne; Nilsen, Roy Miodini; de Marco, Roberto (Peer reviewed; Journal article, 2014-04-16)
      Background: Selection bias is a systematic error in epidemiologic studies that may seriously distort true measures of associations between exposure and disease. Observational studies are highly susceptible to selection ...
    • Maternal and paternal tuberculosis is associated with increased asthma and respiratory symptoms in their offspring: a study from Northern Europe 

      Gyawali, Sanjay; Lopez Cervantes, Juan Pablo; Johannessen, Ane; Gislason, Thorarinn; Holm, Mathias; Janson, Christer; Jögi, Rain; Modig, Lars; Schlünssen, Vivi; Mustafa, Tehmina; Svanes, Cecilie (Journal article; Peer reviewed, 2023)
      Background: Given the profound impact of tuberculosis (TB) on immunity and given murine studies suggesting that infections may influence immunity across generations, we hypothesize that parental TB might impact health and ...
    • Maternal preconception occupational exposure to cleaning products and disinfectants and offspring asthma 

      Tjalvin, Gro; Svanes, Øistein; Igland, Jannicke; Bertelsen, Randi Jacobsen; Benediktsdóttir, Bryndís; Dharmage, Shyamali; Forsberg, Bertil; Holm, Mathias; Janson, Christer; Jögi, Nils Oskar; Johannessen, Ane; Malinovschi, Andrei; Pape, Kathrine; Real, Francisco Gomez; Sigsgaard, Torben; Torén, Kjell; Vindenes, Hilde Kristin; Zock, Jan-Paul; Schlünssen, Vivi; Svanes, Cecilie (Journal article; Peer reviewed, 2021)
      Background Emerging research suggests health effects in offspring after parental chemical exposures before conception. Many future mothers are exposed to potent chemicals at work, but potential offspring health effects ...
    • Menopause as a predictor of new-onset asthma 

      Triebner, Kai; Johannessen, Ane; Puggini, Luca; Benediktsdottir, Bryndis; Bertelsen, Randi Jacobsen; Bifulco, Ersilia; Dharmage, Shyamali C.; Franklin, Karl A.; Gislason, Þórarinn; Holm, Mathias; Jarvis, Deborah; Leynaert, Bénédicte; Lindberg, Eva; Macsali, Ferenc; Malinovschi, Andrej; Norbäck, Dan; Omenaas, Ernst; Rodriguez, Francisco J; Saure, Eirunn Waatevik; Schlünssen, Vivi; Sigsgaard, Torben; Skorge, Trude Duelien; Wieslander, Gunilla; Zemp, Elisabeth; Svanes, Cecilie; Hustad, Simon Steinar; Gomez Real, Francisco (Peer reviewed; Journal article, 2015-01)
      Background: There is limited and conflicting evidence on the effect of menopause on asthma. Objectives: We sought to study whether the incidence of asthma and respiratory symptoms differ by menopausal status in a longitudinal ...
    • Parental Prepuberty Overweight and Offspring Lung Function 

      Lønnebotn, Marianne; Calciano, Lucia; Johannessen, Ane; Jarvis, Deborah L; Abramson, Michael J.; Benediktsdottir, Bryndis; Bråbäck, Lennart; Franklin, Karl A.; Godoy, Raúl; Holm, Mathias; Janson, Christer; Jögi, Nils Oskar; Kirkeleit, Jorunn; Malinovschi, Andrei; Pereira-Vega, Antonio; Schlunssen, Vivi; Dharmage, Shyamali C.; Accordini, Simone; Real, Francisco Gomez; Svanes, Cecilie (Journal article; Peer reviewed, 2022)
      In a recent study we found that fathers’ but not mothers’ onset of overweight in puberty was associated with asthma in adult offspring. The potential impact on offspring’s adult lung function, a key marker of general and ...
    • Parental TB associated with offspring asthma and rhinitis 

      Lopez Cervantes, Juan Pablo; Shigdel, Rajesh; Accordini, S.; Mustafa, Tehmina; Bertelsen, Randi Jacobsen; Makvandi-Nejad, Shokouh; Lerm, M.; Horsnell, W.; Svanes, Cecilie (Journal article; Peer reviewed, 2022)
      BACKGROUND: Infections in early life are associated with asthma and allergies in one-generation settings; however, the link between parental infection and offspring phenotype is rarely investigated. We aim to study the ...
    • Parents’ smoking onset before conception as related to body mass index and fat mass in adult offspring: Findings from the RHINESSA generation study 

      Knudsen, Gerd Toril Mørkve; Dharmage, Shyamali C.; Janson, Christer; Abramson, Michael J.; Benediktsdóttir, Bryndís; Malinovschi, Andrei; Skulstad, Svein Magne; Bertelsen, Randi Jacobsen; Real, Francisco Gomez; Schlünssen, Vivi; Jögi, Nils Oskar; Sánchez-Ramos, José Luis; Holm, Mathias; Garcia-Aymerich, Judith; Forsberg, Bertil; Svanes, Cecilie; Johannessen, Ane (Journal article; Peer reviewed, 2020)
      Emerging evidence suggests that parents’ preconception exposures may influence offspring health. We aimed to investigate maternal and paternal smoking onset in specific time windows in relation to offspring body mass index ...
    • Periodontal Health status and lung function in two Norwegian cohorts 

      Perez Barrionuevo, Antonio Manuel; Gomez Real, Francisco; Igland, Jannicke; Johannessen, Ane; Omenaas, Ernst; Franklin, Karl A.; Barrionuevo, Laura Perez; Åstrøm, Anne Nordrehaug; Svanes, Cecilie; Bertelsen, Randi Jacobsen (Peer reviewed; Journal article, 2018-01-19)
      Rationale and objectives: The oral cavity is united with the airways, and thus poor oral health may affect respiratory health. However, data on the interaction of periodontal and respiratory health is limited. We aimed to ...