• Simple limbal epithelial transplantation: Current status and future perspectives 

      Jackson, Catherine; Ernø, Ina Myklebust; Ringstad, Håkon; Tønseth, Kim Alexander; Dartt, Darlene Ann; Utheim, Tor Paaske (Peer reviewed; Journal article, 2019-12-04)
      Damage to limbal stem cells as a result of injury or disease can lead to limbal stem cell deficiency (LSCD). This disease is characterized by decreased vision that is often painful and may progress to blindness. Clinical ...
    • Stem cell function is conserved during shortterm storage of cultured epidermal cell sheets at 12˚C 

      Ringstad, Håkon; Reppe, Sjur; Schøyen, Tine Hiorth; Tønseth, Kim Alexander; Utheim, Tor Paaske; Jackson, Catherine (Journal article; Peer reviewed, 2020)
      Transplantation of cultured epidermal cell sheets (CES) can be life-saving for patients with large area burns. CES have also been successfully used to regenerate eye and urethral epithelia in animal models. Short-term ...
    • Tear metabolomics in dry eye disease: A review 

      Yazdani, Mazyar; Elgstøen, Katja B. Prestø; Rootwelt, Helge; Shahdafar, Aboulghassem; Utheim, Øygunn Aass; Utheim, Tor Paaske (Peer reviewed; Journal article, 2019-08-01)
      Dry eye disease (DED) is a multifactorial syndrome that can be caused by alteration in the quality or quantity of the precorneal tear film. It is considered one of the most common ocular conditions leading patients to seek ...
    • Tear production levels and dry eye disease severity in a large Norwegian cohort 

      Yazdani, Mazyar; Chen, Xiangjun; Tashbayev, Behzod; Utheim, Øygunn Aass; Ræder, Sten; Lagli, Neil; Stojanovic, Aleksandar; Dartt, Darlene Ann; Utheim, Tor Paaske (Peer reviewed; Journal article, 2018)
      Purpose: To determine if the Schirmer I test (without anesthesia) cut-off value is a predictor of dry eye severity in a large Norwegian cohort of dry eye disease (DED) patients, which are grouped into six levels of tear ...
    • Topical glaucoma medications – Clinical implications for the ocular surface 

      Fineide, Fredrik; Lagali, Neil Satish; Adil, Muhammed Yasin; Arita, Reiko; Kolko, Miriam; Vehof, Jelle; Utheim, Tor Paaske (Journal article; Peer reviewed, 2022)
      Glaucoma is a leading cause of irreversible blindness. The use of topical eye drops to reduce intraocular pressure remains the mainstay treatment. These eye drops frequently contain preservatives designed to ensure sterility ...
    • Video display terminal use and dry eye: preventive measures and future perspectives 

      Kamøy, Bjørnar; Magnø, Morten Scherven; Tellefsen Nøland, Sara Julie Maria; Moe, Morten Carsten; Petrovski, Goran; Vehof, Jelle; Utheim, Tor Paaske (Journal article; Peer reviewed, 2022)
      Background: Dry eye disease (DED) is a common cause of ocular pain and discomfort. Dry eye disease (DED) stems from a loss-of-tear film homeostasis and is frequently seen in video display terminal (VDT) users. Video display ...