Blar i Bergen Open Research Archive på tidsskrift "Science Advances"

Viser treff 21-26 av 26

    • North Atlantic surface ocean warming and salinization in response to middle Eocene greenhouse warming 

      van der Ploeg, Robin; Cramwinckel, Margot J.; Kocken, Ilja J.; Leutert, Thomas Jan; Bohaty, Steven M.; Fokkema, Chris D.; Hull, Pincelli M.; Meckler, Anna Nele; Middelburg, Jack J.; Müller, Inigo A.; Penman, Donald E.; Peterse, Francien; Reichart, Gert-Jan; Sexton, Philip F.; Vahlenkamp, Maximilian; De Vleeschouwer, David; Wilson, Paul A.; Ziegler, Martin; Sluijs, Appy (Journal article; Peer reviewed, 2023)
      Quantitative reconstructions of hydrological change during ancient greenhouse warming events provide valuable insight into warmer-than-modern hydrological cycles but are limited by paleoclimate proxy uncertainties. We ...

    • PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities 

      Đukić, Nina; Strømland, Øyvind; Elsborg, Jonas Damgaard; Munnur, Deeksha; Zhu, Kang; Schuller, Marion; Chatrin, Chatrin; Kar, Pulak; Duma, Lena; Suyari, Osamu; Rack, Johannes Gregor Matthias; Baretić, Domagoj; Crudgington, Dorian Richard Kenneth; Groslambert, Joséphine; Fowler, Gerissa; Wijngaarden, Sven; Prokhorova, Evgeniia; Rehwinkel, Jan; Schüler, Herwig; Filippov, Dmitri V.; Sanyal, Sumana; Ahel, Dragana; Nielsen, Michael L.; Smith, Rebecca; Ahel, Ivan (Journal article; Peer reviewed, 2023)
      PARP14 is a mono–ADP-ribosyl transferase involved in the control of immunity, transcription, and DNA replication stress management. However, little is known about the ADP-ribosylation activity of PARP14, including its ...

    • Postglacial species arrival and diversity buildup of northern ecosystems took millennia 

      Alsos, Inger Greve; Rijal, Dilli Prasad; Ehrich, Dorothee; Karger, Dirk Nikolaus; Yoccoz, Nigel; Heintzman, Peter D.; Brown, Antony; Lammers, Youri; Pellissier, Loïc; Alm, Torbjørn; Bråthen, Kari Anne; Coissac, Eric; Merkel, Marie Føreid; Alberti, Adriana; Denoeud, France; Bakke, Jostein (Journal article; Peer reviewed, 2022)
      What drives ecosystem buildup, diversity, and stability? We assess species arrival and ecosystem changes across 16 millennia by combining regional-scale plant sedimentary ancient DNA from Fennoscandia with near-complete ...

    • Pushing the limits of photoreception in twilight conditions: The rod-like cone retina of the deep-sea pearlsides 

      Busserolles de, Fanny; Cortesi, Fabio; Helvik, Jon Vidar; Davies, Wayne I. L.; Templin, Rachel M.; Sullivan, Robert K. P.; Michell, Craig T.; Mountford, Jessica K.; Collin, Shaun P.; Irigoien, Xabier; Kaartvedt, Stein; Marshall, Justin (Peer reviewed; Journal article, 2017)
      Most vertebrates have a duplex retina comprising two photoreceptor types, rods for dim-light (scotopic) vision and cones for bright-light (photopic) and color vision. However, deep-sea fishes are only active in dim-light ...

    • Sedimentary ancient DNA shows terrestrial plant richness continuously increased over the Holocene in northern Fennoscandia 

      Rijal, Dilli Prasad; Heintzman, Peter D.; Lammers, Youri; Yoccoz, Nigel; Lorberau, Kelsey; Pitelkova, Iva; Goslar, Tomasz; Murguzur, Francisco Javier Ancin; Salonen, J. Sakari; Helmens, Karin F.; Bakke, Jostein; Edwards, Mary E.; Alm, Torbjørn; Bråthen, Kari Anne; Brown, Antony; Alsos, Inger Greve (Journal article; Peer reviewed, 2021)
      The effects of climate change on species richness are debated but can be informed by the past. Here, we generated a sedimentary ancient DNA dataset covering 10 lakes and applied novel methods for data harmonization. We ...

    • Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal 

      Svensson, Mattias N.D.; Zoccheddu, Martina; Yang, Shen; Nygaard, Gyrid; Secchi, Christian; Doody, Karen M.; Slowikowski, Kamil; Mizoguchi, Fumitaka; Humby, Frances; Hands, Rebecca; Santelli, Eugenio; Sacchetti, Cristiano; Wakabayashi, Kuninobu; Wu, Dennis J.; Barback, Christopher; Ai, Rizi; Wang, Wei; Sims, Gary P.; Mydel, Piotr Mateusz; Kasama, Tsuyoshi; Boyle, David L.; Galimi, Francesco; Vera, David; Tremblay, Michel L.; Raychaudhuri, Soumya; Brenner, Michael B.; Firestein, Gary S.; Pitzalis, Costantino; Ekwall, Anna-Karin H.; Stanford, Stephanie M.; Bottini, Nunzio (Journal article; Peer reviewed, 2020)
      Fibroblast-like synoviocytes (FLS) are joint-lining cells that promote rheumatoid arthritis (RA) pathology. Current disease-modifying antirheumatic agents (DMARDs) operate through systemic immunosuppression. FLS-targeted ...