Blar i Bergen Open Research Archive på tittel
Viser treff 20307-20326 av 34059
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Molecular and morphological revision of Afrotropical Hypoborini (Coleoptera: Curculionidae: Scolytinae) revealed novel bark beetle taxa with narrow geographical distributions
(Journal article; Peer reviewed, 2021)Species in the bark beetle tribe Hypoborini Nüsslin, 1912 occur in dead twigs and branches, mainly in dry forest. The Afrotropical fauna previously included ten species in five genera. A taxonomic revision based on molecular ... -
Molecular and phenotypic characteristics influencing the degree of cytoreduction in high-grade serous ovarian carcinomas
(Journal article; Peer reviewed, 2023)Background: High-grade serous ovarian carcinoma (HGSOC) is the deadliest ovarian cancer subtype, and survival relates to initial cytoreductive surgical treatment. The existing tools for surgical outcome prediction remain ... -
Molecular approaches to the diagnosis and evaluation of follicular lymphoma
(Doctoral thesis, 2015-05-27)Background: Molecular studies of immunoglobulin (IG) genes have provided insights into the pathogenesis of different lymphoid malignancies and allowed the development of useful diagnostic tools as well as powerful prognostic ... -
Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK
(Journal article; Peer reviewed, 2020-02)The human N-terminal acetyltransferase E (NatE) contains NAA10 and NAA50 catalytic, and NAA15 auxiliary subunits and associates with HYPK, a protein with intrinsic NAA10 inhibitory activity. NatE co-translationally acetylates ... -
Molecular biology in pancreatic ductal adenocarcinoma: implications for future diagnostics and therapy
(Peer reviewed; Journal article, 2019)Background: Novel technology has enabled researchers to better characterize pancreatic cancers at the molecular level. We wanted to explore some of the emerging discoveries, such as molecular subclassification, use of ... -
Molecular Biomarkers in Thyroid Eye Disease: A Literature Review
(Journal article; Peer reviewed, 2023)Purpose: Thyroid eye disease (TED) is the most common extrathyroidal manifestation of Graves disease. Patients may be severely affected with eyelid retraction, exophthalmos, diplopia, pain, and threatened vision. ... -
Molecular characterisation of key components of the mucosal immune system in Atlantic salmon (Salmo salar L) and transcriptome analysis of responses against the salmon louse (Lepeophtheirus salmonis)
(Doctoral thesis, 2012-04-17)Mucosal immunity in mammals is mediated mainly by secretory immunoglobulin A (SIgA), which is produced by IgA plasma cells commonly located in the lamina propria, and a transport system involving the polymeric Ig receptor ... -
Molecular characterisation of the first New Delhi metallo-β-lactamase 1-producing Acinetobacter baumannii from Tanzania
(Journal article; Peer reviewed, 2021)Background We aimed to characterise the genetic determinants and context of two meropenem-resistant clinical isolates of Acinetobacter baumannii isolated from children hospitalised with bloodstream infections in Dar es ... -
Molecular characterisation of the salmon louse, Lepeophtheirus salmonis salmonis (Krøyer, 1837), ecdysone receptor with emphasis on functional studies of female reproduction
(Peer reviewed; Journal article, 2015-02)The salmon louse Lepeophtheirus salmonis (Copepoda, Caligidae) is an important parasite in the salmon farming industry in the Northern Hemisphere causing annual losses of hundreds of millions of dollars (US) worldwide. To ... -
Molecular characterisaton of T cell co-receptors CD3, CD8 and CD4 in Atlantic salmon (Salmo salar)
(Doctoral thesis, 2009-03-27)The commercial importance of Atlantic salmon (Salmo salar) in aquaculture has fuelled much research into fish health since outbreaks of infectious disease cause major financial losses. All aspects of immunology are therefore ... -
The molecular characteristics of high-grade gastroenteropancreatic neuroendocrine neoplasms
(Journal article; Peer reviewed, 2021)High-grade (HG) gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) are rare but have a very poor prognosis and represent a severely understudied class of tumours. Molecular data for HG GEP-NEN are limited, and ... -
Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis
(Journal article; Peer reviewed, 2020-01-10)Background: We have reported that BRAF V600E mutations and microsatellite instability-high (MSI-H) are more prevalent in a population-based cohort of metastatic colorectal cancer (mCRC) patients than has been reported from ... -
Molecular characterization of an environmental bacterial isolate with strong serological cross-reaction with Shigella boydii 15. Implications for live shigellosis vaccine development
(Master thesis, 2009-04-07)Bacillary dysentery caused by Shigella bacteria (shigellosis) is a major health problem in developing countries. Even though contaminated drinking water is expected to play an important role for the dissemination of this ... -
Molecular characterization of antibiotic resistant bacteria in newly HIV diagnosed adults in a community setting in Tanzania. Implications for infection prevention and control in HIV : Antibiotic resistant bacteria, HIV, Community, Sub-Saharan Africa
(Doctoral thesis, 2022-08-26)Mennesker som lever med HIV-infeksjon i utviklingsland har økt risiko for å bli smittet med antibiotikaresistente bakterier. Høyere forbruk av antibiotika på grunn av HIV-relatert sykdom gir et seleksjonspress som kan føre ... -
Molecular characterization of Corynebacterium diphtheriae isolates, Russia, 1957-1987
(Peer reviewed; Journal article, 2002)In the 1990s, the Newly Independent and Baltic States of the former Soviet Union experienced the largest diphtheria outbreak since the 1960s; it was caused by Corynebacterium diphtheriae strains of a unique clonal group. ... -
Molecular characterization of the apical organ of the anthozoan Nematostella vectensis
(Journal article; Peer reviewed, 2014-12-03)Apical organs are sensory structures present in many marine invertebrate larvae where they are considered to be involved in their settlement, metamorphosis and locomotion. In bilaterians they are characterised by a tuft ... -
Molecular characterization of the lipophorin receptor in the crustacean ectoparasite Lepeophtheirus salmonis
(Peer reviewed; Journal article, 2018-04-12)The Salmon louse (Lepeophtheirus salmonis) is a marine ectoparasite of salmonid fish in the Northern Hemisphere and considered as a major challenge in aquaculture and a threat to wild populations of salmonids. Adult female ... -
Molecular characterization of the myoliquefactive fish parasite kudoa mirabilis (Cnidaria, kudoidae) from se Indian Ocean and its phylogenetic relationship with the kudoa thyrsites species complex
(Journal article; Peer reviewed, 2020)Myxosporean parasites of the genus Kudoa are fish parasites of great economic importance, as some species can affect the fish fillet quality by producing macroscopic cysts or generating post mortem myoliquefaction, commonly ... -
Molecular composition and function of integrin-based collagen glues—Introducing COLINBRIs
(Peer reviewed; Journal article, 2014-08)Background: Despite detailed knowledge about the structure and signaling properties of individual collagen receptors, much remains to be learned about how these receptors participate in linking cells to fibrillar collagen ... -
Molecular crosstalk between cancer cells and tumor microenvironment components suggests potential targets for new therapeutic approaches in mobile tongue cancer
(Peer reviewed; Journal article, 2012)We characterized tumor microenvironment (TME) components of mobile tongue (MT) cancer patients in terms of overall inflammatory infiltrate, focusing on the protumorigenic/anti-inflammatory phenotypes and on cancer-associated ...