Browsing Bergen Open Research Archive by Title

Now showing items 2357-2376 of 35963

    • Axis patterning by BMPs: cnidarian network reveals evolutionary constraints 

      Genikhovich, Grigory; Fried, Patrick; Prünster, M. Mandela; Schinko, Johannes B.; Gilles, Anna F.; Fredman, David; Meier, Karin; Iber, Dagmar; Technau, Ulrich (Peer reviewed; Journal article, 2015-03)
      BMP signaling plays a crucial role in the establishment of the dorso-ventral body axis in bilaterally symmetric animals. However, the topologies of the bone morphogenetic protein (BMP) signaling networks vary drastically ...

    • AXL is a driver of stemness in normal mammary gland and breast cancer 

      Engelsen, Agnete; Wnuk-Lipinska, Katarzyna; Bougnaud, Sébastien; Vatter, Fanny A. Pelissier; Tiron, Crina Elena; Villadsen, René; Miyano, Masaru; Lotsberg, Maria Lie; Madeleine, Noëlly; Panahandeh, Pouda; Dhakal, Sushil; Tan, Tuan Zea; Peters, Stacey D'Mello; Grøndal, Sturla Magnus; Aziz, Sura Mohammed; Nord, Silje; Herfindal, Lars; Stampfer, Martha R.; Sørlie, Therese; Brekken, Rolf A; Straume, Oddbjørn; Halberg, Nils; Gausdal, Gro; Thiery, Jean Paul; Akslen, Lars A.; Petersen, Ole W.; LaBarge, Mark A.; Lorens, James (Journal article; Peer reviewed, 2020)
      The receptor tyrosine kinase AXL is associated with epithelial plasticity in several solid tumors including breast cancer and AXL-targeting agents are currently in clinical trials. We hypothesized that AXL is a driver of ...

    • AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells 

      Lotsberg, Maria Lie; Wnuk-Lipinska, Katarzyna; Terry, Stéphane; Tan, Tuan Zea; Lu, Ning; Trachsel-Moncho, Laura; Røsland, Gro Vatne; Siraji, Muntequa Ishtiaq; Hellesøy, Monica; Rayford, Austin James; Jacobsen, Kirstine; Ditzel, Henrik J; Vintermyr, Olav Karsten; Bivona, Trever G; Minna, John; Brekken, Rolf A; Baguley, Bruce; Micklem, David; Akslen, Lars A.; Gausdal, Gro; Simonsen, Anne; Thiery, Jean Paul; Chouaib, Salem; Lorens, James; Engelsen, Agnete (Journal article; Peer reviewed, 2020)
      Introduction Acquired cancer therapy resistance evolves under selection pressure of immune surveillance and favors mechanisms that promote drug resistance through cell survival and immune evasion. AXL receptor tyrosine ...

    • AXL targeting by a specific small molecule or monoclonal antibody inhibits renal cell carcinoma progression in an orthotopic mice model 

      Chen, Tony Jialiang; Mydel, Piotr Mateusz; Benedyk-Machaczka, Małgorzata; Kamińska, Marta; Kalucka, Urszula; Blø, Magnus; Furriol, Jessica; Gausdal, Gro; Lorens, James Bradley; Osman, Tarig Al-Hadi; Marti, Hans Peter (Journal article; Peer reviewed, 2021)
      AXL tyrosine kinase activation enhances cancer cell survival, migration, invasiveness, and promotes drug resistance. AXL overexpression is typically detected in a high percentage of renal cell carcinomas (RCCs) and is ...

    • AXL targeting reduces fibrosis development in experimental unilateral ureteral obstruction 

      Landolt, Lea Zoe; Furriol, Jessica; Babickova, Janka; Ahmed, Lavina; Eikrem, Øystein Solberg; Skogstrand, Trude; Scherer, Andreas; Suliman, Salwa; Leh, Sabine Maria; Lorens, James; Gausdal, Gro; Marti, Hans-Peter; Osman, Tarig Al-Hadi (Peer reviewed; Journal article, 2019)
      The AXL receptor tyrosine kinase (RTK) is involved in partial epithelial-tomesenchymal transition (EMT) and inflammation – both main promoters of renal fibrosis development. The study aim was to investigate the role of AXL ...

    • AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells 

      Li, Huiyu; Liu, Zhida; Liu, Longchao; Zhang, Hongyi; Han, Chuanhui; Girard, Luc; Park, Hyunsil; Zhang, Anli; Dong, Chunbo; Ye, Jianfeng; Rayford, Austin James; Peyton, Michael; Li, Xiaoguang; Avila, Kimberley; Cao, Xuezhi; Hu, Shuiqing; Alam, Md Maksudul; Akbay, Esra A.; Solis, Luisa M.; Behrens, Carmen; Hernandez-Ruiz, Sharia; Lu, Wei; Wistuba, Ignacio; Heymach, John V.; Chisamore, Michael; Micklem, David Robert; Gabra, Hani; Gausdal, Gro; Lorens, James; Li, Bo; Fu, Yang-Xin; Minna, John D.; Brekken, Rolf A. (Journal article; Peer reviewed, 2022)
      Mutations in STK11/LKB1 in non-small cell lung cancer (NSCLC) are associated with poor patient responses to immune checkpoint blockade (ICB), and introduction of a Stk11/Lkb1 (L) mutation into murine lung adenocarcinomas ...

    • Axl-inhibitor bemcentinib alleviates mitochondrial dysfunction in the unilateral ureter obstruction murine model 

      Hoel, August; Osman, Tarig; Hoel, Fredrik; Elsaid, Hassan Osman Alhassan; Chen, Tony; Landolt, Lea Zoe; Babickova, Janka; Tronstad, Karl Johan; Lorens, James B.; Gausdal, Gro; Marti, Hans-Peter; Furriol, Jessica (Journal article; Peer reviewed, 2021)
      Renal fibrosis is a progressive histological manifestation leading to chronic kidney disease (CKD) and associated with mitochondrial dysfunction. In previous work, we showed that Bemcentinib, an Axl receptor tyrosine kinase ...

    • Azimuthal anisotropy of charged jet production in \(\sqrt{s_{\rm NN}}=2.76\) TeV Pb–Pb collisions 

      Adam, Jaroslav; Adamová, Dagmar; Aggarwal, Madan M.; Aglieri Rinella, Gianluca; Agnello, Michelangelo; Agrawal, Nikita; Ahammed, Zubayer; Ahn, Sang Un; Akindinov, Alexander; Alam, Sk Noor; Alme, Johan; Helstrup, Håvard; Hetland, Kristin Fanebust; Kileng, Bjarte; Altinpinar, Sedat; Djuvsland, Øystein; Haaland, Øystein Senneset; Huang, Meidana; Lønne, Per-Ivar; Nystrand, Joakim; Rehman, Attiq ur; Røhrich, Dieter; Tambave, Ganesh Jagannath; Ullaland, Kjetil; Velure, Arild; Wagner, Boris; Zhang, Hui; Zhou, Zhuo; Arsene, Ionut Christian; Bätzing, Paul Christoph; Dordic, Olja; Lindal, Svein; Mahmood, Sohail Musa; Milosevic, Jovan; Qvigstad, Henrik; Richter, Matthias Rudolph; Røed, Ketil; Skaali, Toralf Bernhard; Tveter, Trine Spedstad; Wikne, Jon Christopher; Zhao, Chengxin; Langøy, Rune; Lien, Jørgen André; Aleksandrov, Dimitry; Alessandro, Bruno; Alexandre, Didier; Alfaro, Molina; Zhu, Hongsheng; Alici, Andrea; Alkin, Anton; ALICE, Collaboration (Peer reviewed; Journal article, 2016-02)
      This paper presents measurements of the azimuthal dependence of charged jet production in central and semi-central \(\sqrt{s_{\rm NN}}=2.76\) TeV Pb–Pb collisions with respect to the second harmonic event plane, quantified ...

    • Azimuthal anisotropy of D-meson production in Pb-Pb collisions at √sNN =2.76 TeV 

      Abelev, Betty; Adam, Jaroslav; Adamová, Dagmar; Aggarwal, Madan M.; Agnello, Michelangelo; Agostinelli, Andrea; Agrawal, Nikita; Ahammed, Zubayer; Ahmad, Nazeer; Ahn, Sang Un; Alme, Johan; Erdal, Hege Austrheim; Helstrup, Håvard; Hetland, Kristin Fanebust; Kileng, Bjarte; Altinpinar, Sedat; Djuvsland, Øystein; Fehlker, Dominik; Haaland, Øystein Senneset; Huang, Meidana; Lønne, Per-Ivar; Nystrand, Joakim; Rehman, Attiq ur; Røhrich, Dieter; Skjerdal, Kyrre; Ullaland, Kjetil; Velure, Arild; Wagner, Boris; Yang, Shiming; Zhou, Zhuo; Arsene, Ionut Christian; Bätzing, Paul Christoph; Dordic, Olja; Lindal, Svein; Mahmood, Sohail Musa; Milosevic, Jovan; Qvigstad, Henrik; Richter, Matthias; Røed, Ketil; Skaali, Toralf Bernhard; Tveter, Trine Spedstad; Wikne, Jon Christopher; Zhao, Chengxin; Langøy, Rune; Lien, Jørgen André; Ahn, Sul-Ah; Ajaz, Muhammad; Akindinov, Alexander; Alt, Torsten; ALICE, Collaboration (Peer reviewed; Journal article, 2014-09)
      The production of the prompt charmed mesons D0, D+, and D*+ relative to the reaction plane was measured in Pb-Pb collisions at a center-of-mass energy per nucleon-nucleon collision of √sNN=2.76TeV with the ALICE detector ...

    • Azimuthal Anisotropy of Heavy-Flavor Decay Electrons in p-Pb Collisions at √sNN=5.02  TeV 

      Acharya, Shreyasi; Adamová, Dagmar; Adolfsson, Jonatan; Aggarwal, Madan M.; Aglieri Rinella, Gianluca; Agnello, Michelangelo; Agrawal, Neelima; Ahammed, Zubayer; Ahn, Sang Un; Aiola, Salvatore; Alme, Johan; Altenkaemper, Lucas; Djuvsland, Øystein; Ersdal, Magnus Rentsch; Fionda, Fiorella Maria Celeste; Nystrand, Joakim; Rehman, Attiq ur; Røhrich, Dieter; Tambave, Ganesh Jagannath; Ullaland, Kjetil; Wagner, Boris; Zhou, Zhuo; Arsene, Ionut Cristian; Bätzing, Paul Christoph; Dordic, Olja; Lardeux, Antoine Xavier; Lindal, Svein; Mahmood, Sohail Musa; Malik, Qasim Waheed; Richter, Matthias; Røed, Ketil; Skaali, Toralf Bernhard; Tveter, Trine Spedstad; Wikne, Jon Christopher; Zhao, Chengxin; Helstrup, Håvard; Hetland, Kristin Fanebust; Kileng, Bjarte; Nesbø, Simon Voigt; Storetvedt, Maksim Melnik; Langøy, Rune; Lien, Jørgen André; Akindinov, Alexander; Al-Turany, Mohammed; Alam, Sk Noor; De Albuquerque, Danilo Silva; Aleksandrov, Dimitry; Alessandro, Bruno; Alfaro Molina, José Rubén; Ali, Yasir Turki Ben; ALICE, Collaboration (Peer reviewed; Journal article, 2019)
      Angular correlations between heavy-flavor decay electrons and charged particles at midrapidity ( | η | < 0.8 ) are measured in p -Pb collisions at √ s N N = 5.02     TeV . The analysis is carried out for the 0%–20% (high) ...

    • Azimuthal correlations of prompt D mesons with charged particles in pp and p–Pb collisions at √sNN=5.02TeV 

      Acharya, Shreyasi; Adamová, Dagmar; Adler, Alexander; Adolfsson, Jonatan; Aggarwal, Madan M.; Aglieri Rinella, Gianluca; Agnello, Michelangelo; Agrawal, Nikita; Ahammed, Zubayer; Ahmad, Shafiq F.; Alme, Johan; Altenkaemper, Lucas; Djuvsland, Øystein; Eikeland, Viljar Nilsen; Ersdal, Magnus Rentsch; Fionda, Fiorella Maria Celeste; Grøttvik, Ola Slettevoll; Lofnes, Ingrid Mckibben; Nystrand, Joakim; Rehman, Attiq Ur; Røhrich, Dieter; Tambave, Ganesh Jagannath; Ullaland, Kjetil; Wagner, Boris; Yang, Shiming; Yuan, Shiming; Zhou, Zhuo; Arsene, Ionut Cristian; Dordic, Olja; Lardeux, Antoine Xavier; Mahmood, Sohail Musa; Malik, Qasim Waheed; Neagu, Alexandra; Richter, Matthias; Røed, Ketil; Skaali, Toralf Bernhard; Tveter, Trine Spedstad; Wikne, Jon Christopher; Helstrup, Håvard; Hetland, Kristin Fanebust; Kileng, Bjarte; Nesbø, Simon Voigt; Storetvedt, Maksim Melnik; Langøy, Rune; Lien, Jørgen André; Ahn, Sang Un; Akindinov, Alexander; Al-Turany, Mohammed; Alam, Sk Noor; De Albuquerque, Danilo Silva; ALICE, Collaboration (Journal article; Peer reviewed, 2020-10-22)
      The measurement of the azimuthal-correlation function of prompt D mesons with charged particles in pp collisions at s√=5.02 TeV and p–Pb collisions at sNN−−−√=5.02 TeV with the ALICE detector at the LHC is reported. The ...

    • Azimuthally differential pion femtoscopy in Pb-Pb collisions at \(\sqrt{s_{\rm NN}}=2.76\) TeV 

      Adamová, Dagmar; Aggarwal, Madan M.; Aglieri Rinella, Gianluca; Agnello, Michelangelo; Agrawal, Nikita; Ahammed, Zubayer; Ahmad, Shafiq F.; Ahn, Sang Un; Aiola, Salvatore; Akindinov, Alexander; Alme, Johan; Helstrup, Håvard; Hetland, Kristin Fanebust; Kileng, Bjarte; Nesbø, Simon Voigt; Altinpinar, Sedat; Djuvsland, Øystein; Lønne, Per-Ivar; Nystrand, Joakim; Rehman, Attiq ur; Røhrich, Dieter; Tambave, Ganesh Jagannath; Ullaland, Kjetil; Velure, Arild; Wagner, Boris; Zhang, Hui; Zhou, Zhuo; Zhu, Hongsheng; Arsene, Ionut Christian; Bätzing, Paul Christoph; Dordic, Olja; Lardeux, Antoine Xavier; Lindal, Svein; Mahmood, Sohail Musa; Milosevic, Jovan; Qvigstad, Henrik; Richter, Matthias; Røed, Ketil; Skaali, Toralf Bernhard; Tveter, Trine Spedstad; Wikne, Jon Christopher; Zhao, Chengxin; Langøy, Rune; Lien, Jørgen André; Alam, Sk Noor; De Albuquerque, Danilo Silva; Aleksandrov, Dimitry; Alessandro, Bruno; Alexandre, Didier; Alfaro Molina, José Rubén; ALICE, Collaboration (Peer reviewed; Journal article, 2017-06)
      We present the first azimuthally differential measurements of the pion source size relative to the second harmonic event plane in Pb-Pb collisions at a center-of-mass energy per nucleon-nucleon pair of \(\sqrt{s_{\rm ...

    • Azimuthally differential pion femtoscopy relative to the second and thrid harmonic in Pb-Pb 2.76 TeV collisions from ALICE 

      Acharya, Shreyasi; Adam, Jaroslav; Adamová, Dagmar; Adolfsson, Jonatan; Aggarwal, Madan M.; Aglieri Rinella, G; Agnello, Michelangelo; Agrawal, Nikita; Ahammed, Zubayer; Ahmad, N; Ahn, SU; Aiola, Salvatore; Akindinov, Alexander; Alam, Sk Noor; Alba, José Luis Bazo; Aleksandrov, Dimitry; Allesandro, B.; Alme, Johan; Altenkaemper, Lucas; Arsene, Ionut Christian; Bätzing, Paul Christoph; Djuvsland, Øystein; Dordic, Olja; Helstrup, Håvard; Hetland, Kristin Fanebust; Kileng, Bjarte; Langøy, Rune; Lardeux, Antoine Xavier; Lien, Jørgen André; Lindal, Svein; Lønne, Per-Ivar; Mahmood, Sohail Musa; Milosevic, Jovan; Nesbø, Simon Voigt; Nystrand, Joakim; Rehman, Attiq Ur; Richter, Matthias Rudolph; Røed, Ketil; Røhrich, Dieter; Skaali, Toralf Bernhard; Tambave, Ganesh Jagannath; Tveter, Trine Spedstad; Ullaland, Kjetil; Velure, Arild; Wagner, Boris; Wikne, Jon Christopher; Zhang, Hui; Zhao, Chengxin; Zhou, Zhuo; Zhu, Hongsheng; ALICE, Collaboration (Peer reviewed; Journal article, 2017-11)
      Azimuthally differential femtoscopic measurements, being sensitive to spatio-temporal characteristics of the source as well as to the collective velocity fields at freeze-out, provide very important information on the ...

    • Azimuthally-differential pion femtoscopy relative to the third harmonic event plane in Pb–Pb collisions at √sNN = 2.76 TeV 

      Acharya, Shreyasi; Acosta, Fernando T.; Adamová, Dagmar; Adolfsson, Jonatan; Aggarwal, Madan M.; Aglieri Rinella, Gianluca; Agnello, Michelangelo; Agrawal, Nikita; Ahammed, Zubayer; Ahn, Sang Un; Alme, Johan; Altenkaemper, Lucas; Djuvsland, Øystein; Ersdal, Magnus Rentsch; Fionda, Fiorella Maria Celeste; Nystrand, Joakim; Rehman, Attiq ur; Røhrich, Dieter; Tambave, Ganesh Jagannath; Ullaland, Kjetil; Velure, Arild; Wagner, Boris; Zhou, Zhuo; Arsene, Ionut Cristian; Bätzing, Paul Christoph; Dordic, Olja; Lardeux, Antoine Xavier; Lindal, Svein; Mahmood, Sohail Musa; Richter, Matthias; Røed, Ketil; Skaali, Toralf Bernhard; Tveter, Trine Spedstad; Wikne, Jon Christopher; Zhao, Chengxin; Helstrup, Håvard; Hetland, Kristin Fanebust; Kileng, Bjarte; Nesbø, Simon Voigt; Storetvedt, Maksim Melnik; Langøy, Rune; Lien, Jørgen André; Aiola, Salvatore; Akindinov, Alexander; Al-Turany, Mohammed; Alam, Sk Noor; De Albuquerque, Danilo Silva; Aleksandrov, Dimitry; Alessandro, Bruno; Alfaro Molina, José Rubén; ALICE, Collaboration (Peer reviewed; Journal article, 2018-06-22)
      Azimuthally-differential femtoscopic measurements, being sensitive to spatio-temporal characteristics of the source as well as to the collective velocity fields at freeze out, provide very important information on the ...

    • À la recherche d’un passé perdu dans L’Art de perdre d’Alice Zeniter 

      Dahl, Maj-Britt (Master thesis, 2023-05-15)
      Hva gjør tapet av familiehistorien med vår opplevelse av identitet og tilhørighet, særlig når historien er så tabubelagt at ingen vil snakke om den? Og hvordan kan litteraturen bidra til å skape forståelse og forsoning i ...

    • Álvaratos, who cares? Ein samfelagsmálvísindalig kanning av hugburði og nýtslu av tøkuorðum og nýggjum orðum í føroyskum 

      Jacobsen, Jógvan í Lon (Doctoral thesis, 2008-11-28)

    • The Āryas’ Dharma and the other. A History of Inclusion and Exclusion Founded on the Brāhmaṇas’ Revelation and Law 

      Alver, Hans Christian (Master thesis, 2015-05-22)
      A historical presentation of Brahmanical texts, and their relation to the "other".

    • «Å beskrive det magiske» En kvalitativ studie av musikklærere i ungdomsskolen sine opplevelser med vurdering av komposisjoner 

      Salthammer, Oda Kristine Stavik (Master thesis, 2023-05-30)
      Dette masterprosjektet har undersøkt hvilke opplevelser musikklærere har med vurdering av komposisjoner i musikkfaget i ungdomsskolen. Det undersøkes også hva de sier de legger vekt på når de vurderer slikt kreativt, ...

    • "Å forandre for å bevare, eller bare for forandringens skyld?" En casestudie av beslutnings- og anskaffelsesprosessen i Forsvarsdepartementet som førte til eksterne konsulenttjenester i 2014. 

      Dvorani, Nicholas Næss (Master thesis, 2021-06-01)
      Forsvarsdepartementet innbydde den 21. juli 2014 til anbudskonkurranse om bistand til modernisering og effektivisering av forsvarssektoren. Denne anbudskonkurransen resulterte i at det private konsulentselskapet «McKinsey ...

    • «Å forme sitt samliv». En metaforteoretisk og retorisk analyse av språkbruk om samliv, ekteskap, drifter og følelser i en kristen, kirkelig tekst. 

      Karlsen, Sarah Strandhus (Master thesis, 2018-10-16)