Browsing Bergen Open Research Archive by Title
Now showing items 2881-2900 of 34095
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Biomarker changes as surrogate endpoints in early-phase trials in heart failure with reduced ejection fraction
(Journal article; Peer reviewed, 2022)Aims No biomarker has achieved widespread acceptance as a surrogate endpoint for early-phase heart failure (HF) trials. We assessed whether changes over time in a panel of plasma biomarkers were associated with subsequent ... -
Biomarker Discovery Using Statistical and Machine Learning Approaches on Gene Expression Data
(Doctoral thesis, 2020-10-30)My PhD is affiliated with the dCod 1.0 project (https://www.uib.no/en/dcod): decoding the systems toxicology of Atlantic cod (Gadus morhua), which aims to better understand how cods adapt and react to the stressors in the ... -
Biomarker profiles in serum and saliva of experimental Sjögren's syndrome: associations with specific autoimmune manifestations
(Peer reviewed; Journal article, 2008-02-20)Introduction Sjögren's syndrome (SS) is a systemic autoimmune disease that mainly targets the exocrine glands. The aim of this study was to investigate the involvement of 87 proteins measured in serum and 75 proteins ... -
Biomarker prognostication of cognitive impairment may be feasible even in out-of hospital cardical arrest survivors with good neurological outcome
(Journal article; Peer reviewed, 2021)Background Patients surviving out-of hospital cardicac arrest, with good neurological outcome according to Cerebral Performance Category, frequently have neuropsychological impairment. We studied whether biomarker data ... -
Biomarker signature and pathophysiological pathways in patients with chronic heart failure and metabolic syndrome
(Journal article; Peer reviewed, 2023)Aim The comorbidities that collectively define metabolic syndrome are common in patients with heart failure. However, the role of metabolic syndrome in the pathophysiology of heart failure is not well understood. We ... -
Biomarkers and Algorithms for the Diagnosis of Vitamin B12 Deficiency
(Peer reviewed; Journal article, 2016-06-27)Vitamin B12 (cobalamin, Cbl, B12) is an indispensable water-soluble micronutrient that serves as a coenzyme for cytosolic methionine synthase (MS) and mitochondrial methylmalonyl-CoA mutase (MCM). Deficiency of Cbl, whether ... -
Biomarkers and echocardiographic predictors of myocardial dysfunction in patients with hypertension
(Peer reviewed; Journal article, 2015-03-09)The study aimed to identify early echocardiographic and circulating biomarkers of heart failure (HF) in hypertensive patients with normal resting echocardiography. Echocardiography at rest and during exercise, and selected ... -
Biomarkers and Fatty Fish Intake: A Randomized Controlled Trial in Norwegian Preschool Children
(Journal article; Peer reviewed, 2021)Background Biomarkers such as omega-3 (n–3) PUFAs, urinary iodine concentration (UIC), 1-methylhistidine (1-MH), and trimethylamine N-oxide (TMAO) have been associated with fish intake in observational studies, but data ... -
Biomarkers and risk factors of neurodegeneration in multiple sclerosis
(Doctoral thesis, 2023-02-10)Bakgrunn og mål: Markører på nevrodegenerasjon er tett knyttet til klinisk funksjonsnedsettelse og sykdomsprogresjon hos pasienter med multippel sklerose (MS). Slike biomarkører kan derfor bidra til å identifisere potensielle ... -
Biomarkers for Diabetes Mellitus in advanced Peripheral Arterial Disease. Diagnostic performance and outcome prediction of HbA1c, fasting plasma glucose and the oral glucose tolerance test
(Doctoral thesis, 2019-05-14)Background: At present, the diagnosis of diabetes mellitus (DM) is based on the result from either of three tests; HbA1c, fasting plasma glucose (FPG) or 2-hour post glucose-load value following an oral glucose tolerance ... -
Biomarkers in breast cancer, with special focus on tumor cell proliferation
(Doctoral thesis, 2016-10-31)Background: Breast cancer is a heterogeneous disease encompassing distinct subtypes that differ in incidence and prognosis. Better characterization of established biomarkers and exploration of novel biomarkers and possible ... -
Biomarkers of inflammation and left ventricular remodelling in psoriasis patients treated with infliximab
(Journal article; Peer reviewed, 2022)Objective: Psoriasis is an immune mediated disorder associated with T cell activation and cardiovascular disease (CVD). We explored the association of inflammation with left ventricular (LV) remodelling in psoriasis patients ... -
Biomarkers of one-carbon metabolism and B-vitamin status : Targeted metabolomics in rats and humans exploring the effects of PPARα-activation and dietary composition
(Doctoral thesis, 2019-10-04)BACKGROUND: One-carbon metabolism is an overarching term describing central metabolic pathways involved in the transfer of one-carbon units. These include the methionine-homocysteine and folate cycles, as well as the choline ... -
Biomarkers related to carotid intima-media thickness and plaques in long-term survivors of ischemic stroke
(Peer reviewed; Journal article, 2015-05-08)Lifestyle risk factors, inflammation and genetics play a role in the development of atherosclerosis. We therefore studied Fc gamma receptor (FcγR) polymorphisms, interleukin (IL)-10 polymorphisms and other biomarkers related ... -
Biomass fuel use for cooking in Nepalese families and child cognitive abilities, results from a community-based study
(Journal article; Peer reviewed, 2022)Background Biomass fuel use for cooking is widespread in low to middle income countries. Studies on the association between biomass fuel use and cognitive abilities in children are limited. Objective To examine the association ... -
Biomass of Scyphozoan Jellyfish, and Its Spatial Association with 0-Group Fish in the Barents Sea
(Peer reviewed; Journal article, 2012-03-22)An 0-group fish survey is conducted annually in the Barents Sea in order to estimate fish population abundance. Data on jellyfish by-catch have been recorded since 1980, although this dataset has never been analysed. In ... -
Biomechanical analysis of groin related strength training exercises for injury prevention
(Master thesis, 2022-07-31)Purpose: Groin injuries in soccer are a widespread problem in sports medicine. One certain strength exercise, the Copenhagen adductor exercise, has shown an injury-preventing effect. But there are still many groin injuries, ... -
Biomedical Image Processing in the Study of Living Cells
(Doctoral thesis, 2008-12-09) -
Biometri og GDPR. Innsamling av biometriske opplysninger med fokus på samtykke som behandlingsgrunnlag.
(Master thesis, 2020-07-11)Den teknologiske utviklingen har de siste årene medført økt bruk av biometriske identifikasjonsmetoder som ansiktsgjenkjenning, fingeravtrykksgjenkjenning og irisgjenkjenning, og har tilsvarende medført et økt behov for ... -
Biomineralisering i kalde grotter: eksempler fra Nordland
(Master thesis, 2019-06-26)Samhandlingen mellom biologi og geologi i grotter er fortsatt lite forstått. Dette gjelder spesielt for biomineralisering; prosessen der mikroorganismer danner mineraler. Med bakgrunn i dette er det i denne oppgaven ...