Browsing Bergen Open Research Archive by Author "Haldorsen, Ingfrid S."
Now showing items 41-60 of 62
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Preoperative 18F-FDG PET/CT tumor markers outperform MRI-based markers for the prediction of lymph node metastases in primary endometrial cancer
Fasmer, Kristine Eldevik; Gulati, Ankush; Dybvik, Julie Andrea; Ytre-Hauge, Sigmund; Salvesen, Øyvind; Trovik, Jone; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2020)Objectives To compare the diagnostic accuracy of preoperative 18F-FDG PET/CT and MRI tumor markers for prediction of lymph node metastases (LNM) and aggressive disease in endometrial cancer (EC). Methods Preoperative ... -
Preoperative CA125 Significantly Improves Risk Stratification in High-Grade Endometrial Cancer
Lombaers, Marike S.; Cornel, Karlijn M. C.; Visser, Nicole C. M.; Bulten, Johan; Küsters-Vandevelde, Heidi V. N.; Amant, Frédéric; Boll, Dorry; Bronsert, Peter; Colas, Eva; Geomini, Peggy M. A. J.; Gil-Moreno, Antonio; van Hamont, Dennis; Huvila, Jutta; Krakstad, Camilla; Kraayenbrink, Arjan A.; Koskas, Martin; Mancebo, Gemma; Matías-Guiu, Xavier; Ngo, Huy; Pijlman, Brenda M.; Vos, Maria Caroline; Weinberger, Vit; Snijders, Marc P. L. M.; van Koeverden, Sebastiaan W.; Haldorsen, Ingfrid S.; Reijnen, Casper; Pijnenborg, Johanna M. A. (Journal article; Peer reviewed, 2023)Patients with high-grade endometrial carcinoma (EC) have an increased risk of tumor spread and lymph node metastasis (LNM). Preoperative imaging and CA125 can be used in work-up. As data on cancer antigen 125 (CA125) in ... -
Preoperative pelvic MRI and 2-[18F]FDG PET/CT for lymph node staging and prognostication in endometrial cancer—time to revisit current imaging guidelines?
Fasmer, Kristine Eldevik; Gulati, Ankush; Dybvik, Julie Andrea; Wagner-Larsen, Kari Strøno; Lura, Njål Gjærde; Salvesen, Øyvind; Forsse, David Erik; Trovik, Jone; Pijnenborg, Johanna M. A.; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2022)Objective This study presents the diagnostic performance of four different preoperative imaging workups (IWs) for prediction of lymph node metastases (LNMs) in endometrial cancer (EC): pelvic MRI alone (IW1), MRI and ... -
Preoperative risk stratification in endometrial cancer (ENDORISK) by a Bayesian network model: A development and validation study
Reijnen, Casper; Gogou, Evangelia; Visser, Nicole C.M.; Engerud, Hilde; Ramjith, Jordache; Van Der Putten, Louis J.M.; Van De Vijver, Koen; Santacana, Maria; Bronsert, Peter; Bulten, Johan; Hirschfeld, Marc; Colas, Eva; Gil-Moreno, Antonio; Reques, Armando; Mancebo, Gemma; Krakstad, Camilla; Trovik, Jone; Haldorsen, Ingfrid S.; Huvila, Jutta; Koskas, Martin; Weinberger, Vit; Bednarikova, Marketa; Hausnerova, Jitka; Van Der Wurff, Anneke A. M.; Matias-Guiu, Xavier; Amant, Frédéric; Massuger, Leon F.A.G.; Snijders, Marc P.L.M.; Küsters-Vandevelde, Heidi V.N.; Lucas, Peter J. F.; Pijnenborg, Johanna M.A. (Journal article; Peer reviewed, 2020)Background Bayesian networks (BNs) are machine-learning–based computational models that visualize causal relationships and provide insight into the processes underlying disease progression, closely resembling clinical ... -
Preoperative tumor size at MRI predicts deep myometrial invasion, lymph node metastases, and patient outcome in endometrial carcinomas
Ytre-Hauge, Sigmund; Husby, Jenny Hild Aase; Magnussen, Inger Johanne; Werner, Henrica Maria Johanna; Salvesen, Øyvind; Bjørge, Line; Trovik, Jone; Stefansson, Ingunn; Salvesen, Helga Birgitte; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2015)OBJECTIVE: The aim of this study was to explore the relation between preoperative tumor size based on magnetic resonance imaging (MRI) and the surgical pathologic staging parameters (deep myometrial invasion, cervical ... -
Primary Central Nervous System Lymphoma in Norway, 1989-2003. Incidence, clinical features, histopathological findings, imaging characteristics, treatment, and outcome in a 15-year national material
Haldorsen, Ingfrid S. (Doctoral thesis, 2009-02-06) -
A radiogenomics application for prognostic profiling of endometrial cancer
Høivik, Erling Andre; Hodneland, Erlend; Dybvik, Julie Andrea; Wagner-Larsen, Kari Strøno; Fasmer, Kristine Eldevik; Berg, Hege Fredriksen; Halle, Mari Kyllesø; Haldorsen, Ingfrid S.; Krakstad, Camilla (Journal article; Peer reviewed, 2021)Prognostication is critical for accurate diagnosis and tailored treatment in endometrial cancer (EC). We employed radiogenomics to integrate preoperative magnetic resonance imaging (MRI, n = 487 patients) with histologic-, ... -
A randomized controlled trial of digital breast tomosynthesis versus digital mammography in population-based screening in Bergen: interim analysis of performance indicators from the To-Be trial
Aase, Hildegunn Siv; Pedersen, Kristin; Houssami, Nehmat; Haldorsen, Ingfrid S.; Sebuødegård, Sofie; Hanestad, Berit; Hofvind, Solveig; Holen, Åsne Sørlien (Peer reviewed; Journal article, 2018-08-29)Objectives To describe a randomized controlled trial (RCT) of digital breast tomosynthesis including synthesized two-dimensional mammograms (DBT) versus digital mammography (DM) in a population-based screening program for ... -
Reduced Pancreatic Volume in Hepatocyte Nuclear Factor 1A-Maturity-Onset Diabetes of the Young
Vesterhus, Mette; Haldorsen, Ingfrid S.; Ræder, Helge; Molven, Anders; Njølstad, Pål Rasmus (Peer reviewed; Journal article, 2008-09)Context: There are interplays between the endocrine and exocrine pancreas. Werecently reported an increased frequency of exocrine dysfunction in HNF1A-maturity-onset diabetes of the young (MODY3) patients, compared with ... -
The role of fat distribution and inflammation in the origin of endometrial cancer, study protocol of the ENDOCRINE study
van den Bosch, den; Pijnenborg, J.M.A.; Romano, A.; Haldorsen, Ingfrid S.; Werner, Henrica Maria Johanna (Journal article; Peer reviewed, 2022)Background Obesity is a growing problem worldwide, especially in countries with improved socioeconomic circumstances. Also, in the Netherlands the incidence of overweight and obesity is rising. There is increasing evidence ... -
Secretin-stimulated ultrasound estimation of pancreatic secretion in cystic fibrosis validated by magnetic resonance imaging
Engjom, Trond; Tjora, Erling; Wathle, Gaute Kjellevold; Erchinger, Friedemann Georg; Lærum, Birger Norderud; Gilja, Odd Helge; Haldorsen, Ingfrid S.; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2018-04)Objectives: Secretin-stimulated magnetic resonance imaging (s-MRI) is the best validated radiological modality assessing pancreatic secretion. The purpose of this study was to compare volume output measures from ... -
Single-cell profiling of low-stage endometrial cancers identifies low epithelial vimentin expression as a marker of recurrent disease
Lien, Hilde Eide; Berg, Hege Fredriksen; Halle, Mari Kyllesø; Trovik, Jone; Haldorsen, Ingfrid S.; Akslen, Lars Andreas; Krakstad, Camilla (Journal article; Peer reviewed, 2023)Background: Identification of aggressive low-stage endometrial cancers is challenging. So far, studies have failed to pinpoint robust features or biomarkers associated with risk of recurrence for these patients. Methods: ... -
Structural imaging findings are related to clinical complications in chronic pancreatitis
Nordaas, Ingrid Kvåle; Tjora, Erling; Dimcevski, Georg Gjorgji; Haldorsen, Ingfrid S.; Olesen, Søren Schou; Drewes, Asbjørn Mohr; Zviniene, Kristina; Barauskas, Giedrius; Bayram, Berivan Kyed; Nørregaard, Peter; Borch, Anders; Nøjgaard, Camilla; Jensen, Annette Bøjer; Kardasheva, Svetlana S.; Okhlobystin, Alexey; Hauge, Truls; Waage, Anne; Frøkjær, Jens Brøndum; Engjom, Trond (Journal article; Peer reviewed, 2022)Background/objectives: Structural pancreatic changes and complications related to chronic pancreatitis are well described, but little is known about their relationship. We aimed to explore the associations between pancreatic ... -
Tissue and imaging biomarkers for hypoxia predict poor outcome in endometrial cancer
Berg, Anna; Fasmer, Kristine Eldevik; Mauland, Karen Klepsland; Ytre-Hauge, Sigmund; Høivik, Erling Andre; Husby, Jenny Hild Aase; Tangen, Ingvild Løberg; Trovik, Jone; Halle, Mari Kyllesø; Woie, Kathrine; Bjørge, Line; Bjørnerud, Atle; Salvesen, Helga; Werner, Henrica Maria Johanna; Krakstad, Camilla; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2016-09-13)Hypoxia is frequent in solid tumors and linked to aggressive phenotypes and therapy resistance. We explored expression patterns of the proposed hypoxia marker HIF-1α in endometrial cancer (EC) and investigate whether ... -
Tumour texture features from preoperative CT predict high-risk disease in endometrial cancer
Ytre-Hauge, Sigmund; Salvesen, Øyvind; Krakstad, Camilla; Trovik, Jone; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2021-01)Background: To enable more individualised treatment of endometrial cancer, improved methods for preoperative tumour characterization are warranted. Texture analysis is a method for quantification of heterogeneity in images, ... -
Two New Mutations in the CEL Gene Causing Diabetes and Hereditary Pancreatitis: How to Correctly Identify MODY8 Cases
Jellas, Khadija el; Dušátková, Petra; Haldorsen, Ingfrid S.; Molnes, Janne; Tjora, Erling; Johansson, Bente Berg; Fjeld, Karianne; Johansson, Stefan; Průhová, Štěpánka; Groop, Leif; Löhr, J. Matthias; Njølstad, Pål Rasmus; Molven, Anders (Journal article; Peer reviewed, 2022)Context Maturity onset diabetes of the young, type 8 (MODY8) is associated with mutations in the CEL gene, which encodes the digestive enzyme carboxyl ester lipase. Several diabetes cases and families have in recent years ... -
Two-view digital breast tomosynthesis versus digital mammography in a population-based breast cancer screening programme (To-Be): a randomised, controlled trial
Hofvind, Solveig; Holen, Åsne Sørlien; Aase, Hildegunn Siv; Houssami, Nehmat; Sebuødegård, Sofie; Moger, Tron Anders; Haldorsen, Ingfrid S.; Akslen, Lars A. (Peer reviewed; Journal article, 2019)Background: Digital breast tomosynthesis is an advancement of mammography, and has the potential to overcome limitations of standard digital mammography. This study aimed to compare first-generation digital breast ... -
Visceral fat percentage for prediction of outcome in uterine cervical cancer
Eide, Agnes J.; Halle, Mari Kyllesø; Lura, Njål; Fasmer, Kristine Eldevik; Wagner-Larsen, Kari Strøno; Forsse, David Erik; Bertelsen, Bjørn; Salvesen, Øyvind Olav; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2023)Objective The prognostic role of adiposity in uterine cervical cancer (CC) is largely unknown. Abdominal fat distribution may better reflect obesity than body mass index. This study aims to describe computed tomography ... -
What is the best preoperative imaging for endometrial cancer?
Haldorsen, Ingfrid S.; Salvesen, Helga (Peer reviewed; Journal article, 2016-04)Although endometrial cancer is surgicopathologically staged, preoperative imaging is recommended for diagnostic work-up to tailor surgery and adjuvant treatment. For preoperative staging, imaging by transvaginal ultrasound ... -
What is the role of imaging at primary diagnostic work-up in uterine cervical cancer?
Haldorsen, Ingfrid S.; Lura, Njål; Blaakær, Jan; Fischerova, Daniela; Werner, Henrica Maria Johanna (Peer reviewed; Journal article, 2019-07-29)Purpose of Review For uterine cervical cancer, the recently revised International Federation of Gynecology and Obstetrics (FIGO) staging system (2018) incorporates imaging and pathology assessments in its staging. In this ...