Blar i Bergen Open Research Archive på forfatter "Smeland, Olav Bjerkehagen"

Viser treff 41-45 av 45

    • Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors 

      Torgersen, Kristin Stensland; Bahrami, Shahram; Frei, Oleksandr; Shadrin, Alexey; O'Connell, Kevin Sean; Smeland, Olav Bjerkehagen; Munkhaugen, John; Djurovic, Srdjan; Dammen, Toril; Andreassen, Ole A. (Journal article; Peer reviewed, 2021)
      Neuroticism is associated with poor health, cardiovascular disease (CVD) risk factors and coronary artery disease (CAD). The conditional/conjunctional false discovery rate method (cond/conjFDR) was applied to genome wide ...

    • Shared genetic architecture between schizophrenia and subcortical brain volumes implicates early neurodevelopmental processes and brain development in childhood 

      Cheng, Weiqiu; van der Meer, Dennis; Parker, Nadine; Hindley, Guy Frederick Lanyon; O'Connell, Kevin Sean; Wang, Yunpeng; Shadrin, Alexey; Alnæs, Dag; Bahrami, Shahram; Lin, Aihua; Karadag, Naz; Holen, Børge; Fernández-Cabello, Sara; Fan, Chun-Chieh; Dale, Anders; Djurovic, Srdjan; Westlye, Lars Tjelta; Frei, Oleksandr; Smeland, Olav Bjerkehagen; Andreassen, Ole (Journal article; Peer reviewed, 2022)
      Patients with schizophrenia have consistently shown brain volumetric abnormalities, implicating both etiological and pathological processes. However, the genetic relationship between schizophrenia and brain volumetric ...

    • The shared genetic basis of mood instability and psychiatric disorders: A cross-trait genome-wide association analysis 

      Hindley, Guy Frederick Lanyon; O'Connell, Kevin Sean; Rahman, Zillur; Frei, Oleksandr; Bahrami, Shahram; Shadrin, Alexey; Høegh, Margrethe Collier; Cheng, Weiqiu; Karadag, Naz; Lin, Aihua; Rødevand, Linn; Fan, Chun C.; Djurovic, Srdjan; Lagerberg, Trine Vik; Dale, Anders; Smeland, Olav Bjerkehagen; Andreassen, Ole (Journal article; Peer reviewed, 2022)
      Recent genome-wide association studies of mood instability (MOOD) have found significant positive genetic correlation with major depression (DEP) and weak correlations with other psychiatric disorders. We investigated the ...

    • Shared genetic loci between depression and cardiometabolic traits 

      Torgersen, Kristin Stensland; Rahman, Zillur; Bahrami, Shahram; Hindley, Guy Frederick Lanyon; Parker, Nadine; Frei, Oleksandr; Shadrin, Alexey; O'Connell, Kevin Sean; Tesli, Martin Steen; Smeland, Olav Bjerkehagen; Munkhaugen, John; Djurovic, Srdjan; Dammen, Toril; Andreassen, Ole (Journal article; Peer reviewed, 2022-05-13)
      Epidemiological and clinical studies have found associations between depression and cardiovascular disease risk factors, and coronary artery disease patients with depression have worse prognosis. The genetic relationship ...

    • Transcriptional and functional effects of lithium in bipolar disorder iPSC-derived cortical spheroids 

      Osete, Jordi Requena; Akkouh, Ibrahim Ahmed; Levglevskyi, Oleksandr; Vandenberghe, Matthieu; Reis de Assis, Denis; Ueland, Thor; Kondratskaya, Elena; Holen, Børge; Szabo, Attila; Hughes, Timothy; Smeland, Olav Bjerkehagen; Steen, Vidar Martin; Andreassen, Ole; Djurovic, Srdjan (Journal article; Peer reviewed, 2023)
      Lithium (Li) is recommended for long-term treatment of bipolar disorder (BD). However, its mechanism of action is still poorly understood. Induced pluripotent stem cell (iPSC)-derived brain organoids have emerged as a ...