Blar i Bergen Open Research Archive på forfatter "Mellgren, Gunnar"
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Short-term effects of Vertical sleeve gastrectomy and Roux-en-Y gastric bypass on glucose homeostasis
Gudbrandsen, Oddrun Anita; Dankel, Simon N; Skumsnes, Lillian; Flølo, Tone Nygaard; Folkestad, Oddry H; Nielsen, Hans Jørgen; Våge, Villy; Mohn, Arne-Christian; Nedrebø, Bjørn Gunnar; Sagen, Jørn V.; Fernø, Johan; Mellgren, Gunnar (Peer reviewed; Journal article, 2019-10-15)The objective of this study was to compare the biochemical changes related to glucose tolerance and lipid metabolism in non-diabetic patients shortly after vertical sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB). ... -
Simultaneous Quantification of Aromatase Inhibitors and Estrogens in Postmenopausal Breast Cancer Patients
Bertelsen, Bjørn-Erik; Viste, Kristin; Helland, Thomas; Hagland, Magnus; Søiland, Håvard; Geisler, Jürgen; Lende, Tone Hoel; Lønning, Per Eystein; Sagen, Jørn Vegard; Mellgren, Gunnar; Almås, Bjørg (Journal article; Peer reviewed, 2021)Context Currently there are no assays that can simultaneously quantify serum levels of the third-generation aromatase inhibitors (AIs): letrozole, anastrozole, and exemestane, and the ultra-low levels of estrogens in ... -
Steroid receptor coactivators, HER-2 and HER-3 expression is stimulated by tamoxifen treatment in DMBA-induced breast cancer
Moi, Line Leonora Haugan; Flågeng, Marianne Hauglid; Gjerde, Jennifer; Madsen, Andre; Røst, Therese Halvorsen; Gudbrandsen, Oddrun Anita; Lien, Ernst Asbjørn; Mellgren, Gunnar (Peer reviewed; Journal article, 2012-06-15)Background: Steroid receptor coactivators (SRCs) may modulate estrogen receptor (ER) activity and the response to endocrine treatment in breast cancer, in part through interaction with growth factor receptor signaling ... -
Subtype-specific surface proteins on adipose tissue macrophages and their association to obesity-induced insulin resistance
Strand, Kristina; Stiglund, Natalie; Haugstøyl, Martha Eimstad; Kamyab, Seyedeh Zahra; Langhelle, Victoria Puntervold; Dyer, Laurence; Busch, Christian; Cornillet, Martin; Hjellestad, Iren Drange; Nielsen, Hans Jørgen; Njølstad, Pål Rasmus; Mellgren, Gunnar; Björkström, Niklas K.; Fernø, Johan (Journal article; Peer reviewed, 2022)A chronic low-grade inflammation, originating in the adipose tissue, is considered a driver of obesity-associated insulin resistance. Macrophage composition in white adipose tissue is believed to contribute to the pathogenesis ... -
Switch from stress response to homeobox transcription factors in Adipose tissue after profound fat loss
Dankel, Simon N; Fadnes, Dag J.; Stavrum, Anne-Kristin; Stansberg, Christine; Holdhus, Rita; Hoang, Tuyen Thi Van; Veum, Vivian L.; Christensen, Bjørn Jostein; Våge, Villy; Sagen, Jørn V.; Steen, Vidar Martin; Mellgren, Gunnar (Peer reviewed; Journal article, 2010-06-09)Background In obesity, impaired adipose tissue function may promote secondary disease through ectopic lipid accumulation and excess release of adipokines, resulting in systemic low-grade inflammation, insulin resistance ... -
Testicular ultrasound to stratify hormone references in a cross-sectional Norwegian study of male puberty
Madsen, Andre; Oehme, Ninnie; Roelants, Mathieu; Bruserud, Ingvild Særvold; Eide, Geir Egil; Viste, Kristin; Bjerknes, Robert; Almås, Bjørg; Rosendahl, Karen; Sagen, Jørn V.; Mellgren, Gunnar; Juliusson, Petur Benedikt (Peer reviewed; Journal article, 2020)Context: Testicular growth represents the best clinical variable to evaluate male puberty, but current pediatric hormone references are based on chronological age and subjective assessments of discrete puberty development ... -
Urine and plasma concentrations of amino acids and plasma vitamin status differ, and are differently affected by salmon intake, in obese Zucker fa/fa rats with impaired kidney function and in Long-Evans rats with healthy kidneys
Drotningsvik, Aslaug; Midttun, Øivind; Vikøren, Linn Anja Slåke; McCann, Adrian; Ueland, Per Magne; Mellgren, Gunnar; Gudbrandsen, Oddrun Anita (Peer reviewed; Journal article, 2019)Kidney function affects amino acid metabolism and vitamin status. The aims of the present study were to investigate urine and plasma concentrations of amino acids as well as plasma vitamin status in rats with impaired renal ...