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DNA polymerase gamma mutations that impair holoenzyme stability cause catalytic subunit depletion
(Journal article; Peer reviewed, 2021)Mutations in POLG, encoding POLγA, the catalytic subunit of the mitochondrial DNA polymerase, cause a spectrum of disorders characterized by mtDNA instability. However, the molecular pathogenesis of POLG-related diseases ... -
DNA Repair Mechanisms are Activated in Circulating Lymphocytes of Hospitalized Covid-19 Patients
(Journal article; Peer reviewed, 2022)Purpose: Reactive oxygen species (ROS) are an important part of the inflammatory response during infection but can also promote DNA damage. Due to the sustained inflammation in severe Covid-19, we hypothesized that ... -
DNA Topoisomerase IIα contributes to the early steps of adipogenesis in 3T3-L1 cells
(Peer reviewed; Journal article, 2016-07-09)DNA topoisomerases (Topo) are multifunctional enzymes resolving DNA topological problems such as those arising during DNA replication, transcription and mitosis. Mammalian cells express 2 class II isoforms, Topoisomerases ... -
A DNA vaccine that targets hemagglutinin to antigen-presenting cells protects mice against H7 influenza
(Peer reviewed; Journal article, 2017-12)Zoonotic influenza H7 viral infections have a case fatality rate of about 40%. Currently, no or limited human to human spread has occurred, but we may be facing a severe pandemic threat if the virus acquires the ability ... -
DNA-analysis to monitor fisheries and aquaculture: Too costly?
(Peer reviewed; Journal article, 2019-03)Evidence from DNA‐analysis is commonplace in human criminal investigations, and while it is increasingly being used in wildlife crime, to date, its application to control and enforcement activities in fisheries and aquaculture ... -
DNA-screening - En vurdering av straffeprosessloven § 158 andre ledd og forholdet til EMK
(Master thesis, 2015-12-10) -
DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease
(Peer reviewed; Journal article, 2014-08-20)Background: Chronic obstructive pulmonary disease (COPD) is characterized by expiratory flow limitation, causing air trapping and lung hyperinflation. Hyperinflation leads to reduced exercise tolerance and poor quality of ... -
Do abnormal serum lipid levels increase the risk of chronic low back pain? The Nord-Trøndelag Health Study
(Peer reviewed; Journal article, 2014-09-18)Background: Cross-sectional studies suggest associations between abnormal lipid levels and prevalence of low back pain (LBP), but it is not known if there is any causal relationship. Objective: The objective was to determine, ... -
Do actions speak louder than words? - Communication and partner choice in the prisoner's dilemma game
(Master thesis, 2018-06-28)Communication has been shown to enhance cooperation (Dawes, McTavish and Shaklee 1977; Isaac and Walker 1988; Sally 1995; Bochet, Page and Putterman 2006). But do all people benefit equally from communication? This thesis ... -
Do ampharetids take sedimented steps between vents and seeps? Phylogeny and habitat-use of Ampharetidae (Annelida, Terebelliformia) in chemosynthesis-based ecosystems
(Peer reviewed; Journal article, 2017-10-31)Background: A range of higher animal taxa are shared across various chemosynthesis-based ecosystems (CBEs), which demonstrates the evolutionary link between these habitats, but on a global scale the number of species ... -
Do citizens make inferences from political candidate characteristics when aiming for substantive representation?
(Peer reviewed; Journal article, 2019)We elicit citizens' preferences over hypothetical candidates by applying conjoint survey experiments within a probability-based online panel of the Norwegian electorate. Our experimental treatments differ in whether citizens ... -
Do Cognitive Processes Influence Social Preferences? Testing the social heuristics hypothesis in a sequential prisoner's dilemma
(Master thesis, 2017-06-09)Is cooperation intuitive or deliberative? From an early notion of cooperation as a deliberate suppression of innate selfish preferences, a growing body of literature has turned the general perception towards prosocial ... -
Do composition and richness of woody plants vary between gaps and closed canopy patches in subtropical forests?
(Peer reviewed; Journal article, 2016)Questions: Do composition and richness of woody plants differ between gaps and closed canopy in subtropical forests, and does this difference vary across life stages of tree species? Is tree species richness in gaps a ... -
Do deformation bands matter forflow? Insights from permeability measurements and flow simulations in porous carbonate rocks
(Peer reviewed; Journal article, 2017-02)We investigate the permeability and flow effects of deformation bands in porous granular carbonate rocks in Malta and use results from flow simulations to discuss the practical implications of deformation bands in carbonate ... -
Do direct oral anticoagulants (DOACs) cause delayed surgery, longer length of hospital stay, and poorer outcome for hip fracture patients?
(Journal article; Peer reviewed, 2020)Purpose The perioperative consequences of direct oral anticoagulants (DOACs) in hip fracture patients are not sufficiently investigated. The primary aim of this study was to determine whether DOAC-users have delayed surgery ... -
Do Disease Stories Need a Hero? Effects of Human Protagonists on a Narrative Visualization about Cerebral Small Vessel Disease
(Journal article; Peer reviewed, 2023)Authors use various media formats to convey disease information to a broad audience, from articles and videos to interviews or documentaries. These media often include human characters, such as patients or treating physicians, ... -
Do ectomycorrhizal exploration types reflect mycelial foraging strategies?
(Journal article; Peer reviewed, 2022)Ectomycorrhizal exploration types are commonly assumed to denote spatial foraging patterns and resource-related niches of extraradical mycelia. However, empirical evidence of the consistency of foraging strategies within ... -
Do environmental effects indexed by parental genetic variation influence common psychiatric symptoms in childhood?
(Journal article; Peer reviewed, 2023)Parental genes may indirectly influence offspring psychiatric outcomes through the environment that parents create for their children. These indirect genetic effects, also known as genetic nurture, could explain individual ... -
Do gastrointestinal complaints increase the risk for subsequent medically certified long-term sickness absence? The HUSK study
(Peer reviewed; Journal article, 2011-07-29)Background: Gastrointestinal complaints are very common in the general population and very often co-occur with common mental disorders. We aimed to study the prospective impact of gastrointestinal complaints on long term ... -
Do Genetic Variants Modify the Effect of Smoking on Risk of Preeclampsia in Pregnancy?
(Journal article; Peer reviewed, 2021)Objective: Maternal smoking is associated with as much as a 50% reduced risk of preeclampsia, despite increasing risk of other poor pregnancy outcomes that often co-occur with preeclampsia, such as preterm birth and fetal ...