Browsing Bergen Open Research Archive by Author "Barry, Alyssa E."

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    • Sulfonylpiperazine compounds prevent Plasmodium falciparum invasion of red blood cells through interference with actin-1/profilin dynamics 

      Dans, Madeline G.; Piirainen, Henni; Nguyen, William; Khurana, Sachin; Mehra, Somya; Razook, Zahra; Geoghegan, Niall D.; Dawson, Aurelie T.; Das, Sujaan; Schneider, Molly Parkyn; Jonsdottir, Thorey K.; Gabriela, Mikha; Gancheva, Maria R.; Tonkin, Christopher J.; Mollard, Vanessa; Goodman, Christopher Dean; McFadden, Geoffrey I.; Wilson, Danny W.; Rogers, Kelly L.; Barry, Alyssa E.; Crabb, Brendan S.; de Koning-Ward, Tania F.; Sleebs, Brad E.; Kursula, Inari Talvikki; Gilson, Paul R. (Journal article; Peer reviewed, 2023)
      With emerging resistance to frontline treatments, it is vital that new antimalarial drugs are identified to target Plasmodium falciparum. We have recently described a compound, MMV020291, as a specific inhibitor of red ...