Browsing Bergen Open Research Archive by Author "Berg, Marianne"
Now showing items 1-6 of 6
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Comparison of CpG Island Methylator Phenotype (CIMP) Frequency in Colon Cancer Using Different Probe- and Gene-Specific Scoring Alternatives on Recommended Multi-Gene Panels
Berg, Marianne; Hagland, Hanne; Søreide, Kjetil (Peer reviewed; Journal article, 2014-01-21)Background: In colorectal cancer a distinct subgroup of tumours demonstrate the CpG island methylator phenotype (CIMP). However, a consensus of how to score CIMP is not reached, and variation in definition may influence ... -
Genetic and Epigenetic Traits as Biomarkers in Colorectal Cancer
Berg, Marianne; Søreide, Kjetil (Peer reviewed; Journal article, 2011-12-16)Colorectal cancer is a major health burden, and a leading cause of cancer-related deaths in industrialized countries. The steady improvements in surgery and chemotherapy have improved survival, but the ability to identify ... -
Influence of microsatellite instability and KRAS and BRAF mutations on lymph node harvest in stage I–III colon cancers
Berg, Marianne; Guriby, Marianne; Nordgård, Oddmund; Nedrebø, Bjørn Steinar Olden; Ahlquist, Terje Cruickshank; Smaaland, Rune; Oltedal, Satu; Søreide, Jon Arne; Kørner, Hartwig; Lothe, Ragnhild A.; Søreide, Kjetil (Peer reviewed; Journal article, 2013)Lymph node (LN) harvest is influenced by several factors, including tumor genetics. Microsatellite instability (MSI) is associated with improved node harvest, but the association to other genetic factors is largely unknown. ... -
Long-term follow-up and survivorship after completing systematic surveillance in stage I–III colorectal cancer: who is still at risk?
Veen, Torhild; Stormark, Kjartan; Nedrebø, Bjørn Steinar Olden; Berg, Marianne; Søreide, Jon Arne; Kørner, Hartwig; Søreide, Kjetil (Peer reviewed; Journal article, 2015-09)Purpose: In patients with a high life expectancy at the time of surgery for colorectal cancer (CRC), the long-term outcome may be influenced by factors other than their cancer. We aimed to investigate the long-term outcome ... -
Molecular subtypes in stage II-III colon cancer defined by genomic instability: Early recurrence-risk associated with a high copy-number variation and loss of RUNX3 and CDKN2A
Berg, Marianne; Nordgård, Oddmund; Kørner, Hartwig; Oltedal, Satu; Smaaland, Rune; Søreide, Jon Arne; Søreide, Kjetil (Peer reviewed; Journal article, 2015-04-16)Objective: We sought to investigate various molecular subtypes defined by genomic instability that may be related to early death and recurrence in colon cancer. Methods: We sought to investigate various molecular subtypes ... -
Prevalence and implications of elevated microsatellite alterations at selected tetranucleotides in cancer
Watson, Martin M; Berg, Marianne; Søreide, Kjetil (Peer reviewed; Journal article, 2014-04-01)Elevated microsatellite alterations at selected tetranucleotides (EMAST), a variation of microsatellite instability (MSI), has been reported in a variety of malignancies (e.g., neoplasias of the lung, head and neck, ...