Blar i Bergen Open Research Archive på forfatter "Langørgen, Jørund"
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Adding stress biomarkers to high-sensitivity cardiac troponin for rapid non-ST-elevation myocardial infarction rule-out protocols
Restan, Ingar Ziad; Sanchez, Ana Yufera; Steiro, Ole-Thomas; Lopez-Ayala, Pedro; Tjora, Hilde Lunde; Langørgen, Jørund; Omland, Torbjørn; Boeddinghaus, Jasper; Nestelberger, Thomas; Koechlin, Luca; Collinson, Paul; Bjørneklett, Rune Oskar; Vikenes, Kjell; Strand, Heidi; Skadberg, Øyvind; Mjelva, Øistein; Larsen, Alf Inge; Vernon, Bonarjee; Mueller, Christian; Aakre, Kristin Moberg (Journal article; Peer reviewed, 2022)Aims This study tested the hypothesis that combining stress-induced biomarkers (copeptin or glucose) with high-sensitivity cardiac troponin (hs-cTn) increases diagnostic accuracy for non-ST-elevation myocardial infarction ... -
Baseline frailty status and outcomes important for shared decision‑making in older adults receiving transcatheter aortic valve implantation, a prospective observational study
Skaar, Elisabeth; Øksnes, Anja; Eide, Leslie SP; Norekvål, Tone Merete; Ranhoff, Anette Hylen; Nordrehaug, Jan Erik; Forman, Daniel Edward; Schoennberger, Andreas W.; Hufthammer, Karl Ove; Kuiper, Karel Kier-Jan; Bleie, Øyvind; Packer, Erik; Langørgen, Jørund; Haaverstad, Rune; Schaufel, Margrethe Aase (Journal article; Peer reviewed, 2021)Aims The objective of this study was to examine baseline frailty status (including cognitive deficits) and important clinical outcomes, to inform shared decision-making in older adults receiving transcatheter aortic valve ... -
Capillary leakage in post-cardiac arrest survivors during therapeutic hypothermia - a prospective, randomised study
Heradstveit, Bård E.; Guttormsen, Anne Berit; Langørgen, Jørund; Hammersborg, Stig-Morten; Wentzel-Larsen, Tore; Fanebust, Rune; Larsson, Elna-Marie; Heltne, Jon-Kenneth (Peer reviewed; Journal article, 2010-05-25)Background: Fluids are often given liberally after the return of spontaneous circulation. However, the optimal fluid regimen in survivors of cardiac arrest is unknown. Recent studies indicate an increased fluid requirement ... -
Cardiac arrest as a reportable condition: A cohort study of the first 6 years of the Norwegian out-of-hospital cardiac arrest registry
Tjelmeland Myrhaugen, Ingvild Beathe; Alm-Kruse, Kristin; Andersson, Lars-Jøran; Bratland, Ståle; Hafstad, Arne Ketil; Haug, Bjørn; Langørgen, Jørund; Larsen, Alf Inge; Lindner, Thomas Werner; Nilsen, Jan Erik; Olasveengen, Theresa Mariero; Søreide, Eldar; Skogvoll, Eirik; Kramer-Johansen, Jo (Journal article; Peer reviewed, 2020)Objectives The Norwegian Cardiac Arrest Registry (NorCAR) was established in 2013 when cardiac arrest became a mandatory reportable condition. The aim of this cohort study is to describe how the world’s first mandatory, ... -
Cardiac Troponin Assays With Improved Analytical Quality: A Trade-Off Between Enhanced Diagnostic Performance and Reduced Long-Term Prognostic Value
Tjora, Hilde Lunde; Steiro, Ole-Thomas; Langørgen, Jørund; Bjørneklett, Rune; Nygård, Ottar; Skadberg, Øyvind; Bonarjee, Vernon; Collinson, Paul; Omland, Torbjørn; Vikenes, Kjell; Aakre, Kristin Moberg (Journal article; Peer reviewed, 2020)Background Cardiac troponin (cTn) permits early rule‐out/rule‐in of patients admitted with possible non–ST‐segment–elevation myocardial infarction. In this study, we developed an admission and a 0/1 hour rule‐out/rule‐in ... -
Cognitive function and health-related quality of life four years after cardiac arrest
Buanes, Eirik Alnes; Gramstad, Arne; Søvig, Karoline Kjellsdotter; Hufthammer, Karl Ove; Flaatten, Hans; Husby, Thomas; Langørgen, Jørund; Heltne, Jon-Kenneth (Peer reviewed; Journal article, 2015-04)Aim: Neuropsychological testing has uncovered cognitive impairment in cardiac arrest survivors with good neurologic outcome according to the cerebral performance categories. We investigated cognitive function and health-related ... -
Diagnostic Performance of Novel Troponin Algorithms for the Rule-Out of Non-ST-Elevation Acute Coronary Syndrome
Tjora, Hilde Lunde; Steiro, Ole-Thomas; Langørgen, Jørund; Bjørneklett, Rune Oskar; Skadberg, Øyvind; Bonarjee, Vernon V S; Mjelva, Øistein; Collinson, Paul; Omland, Torbjørn; Vikenes, Kjell; Aakre, Kristin Moberg (Journal article; Peer reviewed, 2022)Background The European Society of Cardiology (ESC) rule-out algorithms use cutoffs optimized for exclusion of non-ST elevation myocardial infarction (NSTEMI). We investigated these and several novel algorithms for the ... -
Factors predicting the use of therapeutic hypothermia and survival in unconscious out-of-hospital cardiac arrest patients admitted to the ICU
Lindner, Thomas Werner; Langørgen, Jørund; Sunde, Kjetil; Larsen, Alf Inge; Kvaløy, Jan Terje; Heltne, Jon-Kenneth; Drægni, Tomas; Søreide, Eldar (Peer reviewed; Journal article, 2013-07-23)Introduction: Therapeutic hypothermia (TH) after out-of-hospital cardiac arrest (OHCA) was adopted early in Norway. Since 2004 the general recommendation has been to cool all unconscious OHCA patients treated in the intensive ... -
Growth Differentiation Factor 15: A Prognostic Marker in Patients with Acute Chest Pain without Acute Myocardial Infarction
Myrmel, Gard Mikael Saele; Steiro, Ole-Thomas; Tjora, Hilde Lunde; Langørgen, Jørund; Bjørneklett, Rune Oskar; Skadberg, Øyvind; Bonarjee, Vernon V S; Mjelva, Øistein; Pedersen, Eva Ringdal; Vikenes, Kjell; Omland, Torbjørn; Aakre, Kristin Moberg (Journal article; Peer reviewed, 2023)Background Acute chest pain is associated with an increased risk of death and cardiovascular events even when acute myocardial infarction (AMI) has been excluded. Growth differentiation factor-15 (GDF-15) is a strong ... -
Hospitalization for acute myocardial infarction – trends in case fatality, and the impact of changing definition on number of events, subtypes and mortality
Langørgen, Jørund (Doctoral thesis, 2014-09-24)Background: Few studies of acute myocardial infarction (AMI) among hospitalized patients have had direct estimates of long-term case fatality after AMI, and the literature is conflicting regarding gender-related prognosis ... -
A novel Geriatric Assessment frailty score predicts two-year mortality after Transcatheter Aortic Valve implantation
Skaar, Elisabeth; Eide, Leslie Sofia Pareja; Norekvål, Tone M.; Ranhoff, Anette Hylen; Nordrehaug, Jan Erik; Forman, Daniel E.; Schönenberger, Anders; Hufthammer, Karl Ove; Kuiper, Karel Kier-Jan; Bleie, Øyvind; Haaverstad, Rune; Schaufel, Margrethe Aase; Packer, Erik Jerome Stene; Langørgen, Jørund (Peer reviewed; Journal article, 2018-10-31)Aims Established surgical scores have limitations in delineating risk among candidates for transcatheter aortic valve implantation (TAVI). Assessment of frailty might help to estimate the mortality risk and identify patients ... -
The patient experience of in-hospital telemetry monitoring: a qualitative analysis
Holm, Marianne Sætrang; Fålun, Nina Britt; Bendz, Bjørn; Fridlund, Bengt Gotthard Anton; Langørgen, Jørund; Pettersen, Trond Røed; Sandau, Kristin E.; Norekvål, Tone Merete (Journal article; Peer reviewed, 2023)Aims In-hospital telemetry monitoring has been an integrated part of arrhythmia monitoring for decades. A substantial proportion of patients require arrhythmia monitoring during stays in non-intensive care units. However, ... -
Predictors of long-term symptom burden and quality of life in patients hospitalised with chest pain: a prospective observational study
Saeed, Nasir; Norekvål, Tone Merete; Steiro, Ole-Thomas; Tjora, Hilde Lunde; Langørgen, Jørund; Bjørneklett, Rune Oskar; Skadberg, Øyvind; Bonarjee, Vernon V S; Mjelva, Øistein; Omland, Torbjørn; Vikenes, Kjell; Aakre, Kristin Moberg (Journal article; Peer reviewed, 2022)Objective: To describe the magnitude and predictors of symptom burden (SB) and quality of life (QoL) 3 months after hospital admission for acute chest pain. Design: Prospective observational study. Setting: Single ... -
Prognostic significance of chronic myocardial injury diagnosed by three different cardiac troponin assays in patients admitted with suspected acute coronary syndrome
Steiro, Ole-Thomas; Langørgen, Jørund; Tjora, Hilde Lunde; Bjørneklett, Rune Oskar; Skadberg, Øyvind; Bonarjee, Vernon V S; Mjelva, Øistein; Steinsvik, Trude; Lindahl, Bertil; Omland, Torbjørn; Aakre, Kristin Moberg; Vikenes, Kjell (Journal article; Peer reviewed, 2023)Objectives Chronic myocardial injury (CMI) is defined as stable concentrations of cardiac troponin T or I (cTnT or cTnI) above the assay-specific 99th percentile upper reference limit (URL) and signals poor outcome. The ... -
Targeted temperature management in cardiac arrest: survival evaluated by propensity score matching
Buanes, Eirik Alnes; Hufthammer, Karl O.; Langørgen, Jørund; Guttormsen, Anne-Berit; Heltne, Jon-Kenneth (Peer reviewed; Journal article, 2017)Background: Targeted temperature management in cardiac arrest was introduced following evidence of increased survival from two controlled trials published in 2002. We wanted to investigate whether the introduction of ...