• Finite element analysis of mitral valve annuloplasty in Barlow's disease 

      Aguilera, Hans Martin; Urheim, Stig; Persson, Robert; Haaverstad, Rune; Skallerud, Bjørn Helge; Prot, Victorien Emile (Journal article; Peer reviewed, 2022)
      Barlow’s Disease affects the entire mitral valve apparatus causing mitral regurgitation. Standard annuloplasty procedures lead to an average of 55% annular area reduction of the end diastolic pre-operative annular area in ...
    • In silico analysis provides insights for patient-specific annuloplasty in Barlow’s disease 

      Aguilera, Hans Martin Dahl; Persson, Robert; Haaverstad, Rune; Skallerud, Bjørn Helge; Prot, Victorien Emile; Urheim, Stig (Journal article; Peer reviewed, 2023)
      Objective To predict the required mitral annular area reduction in patients with Barlow's disease to obtain a predefined leaflet area index by a novel in silico modeling method. Methods Three-dimensional echocardiography ...
    • Influence of Annular Dynamics and Material Behavior in Finite Element Analysis of Barlow’s Mitral Valve Disease 

      Aguilera, Hans Martin; Urheim, Stig; Skallerud, Bjørn Helge; Prot, Victorien Emile (Journal article; Peer reviewed, 2021)
      Barlow’s disease affects the entire mitral valve apparatus, by altering several of the fundamental mechanisms in the mitral valve which ensures unidirectional blood flow between the left atrium and the left ventricle. In ...
    • Mechanical behavior and collagen structure of degenerative mitral valve leaflets and a finite element model of primary mitral regurgitation 

      Sadeghinia, Mohammadjavad; Aguilera, Hans Martin Dahl; Urheim, Stig; Persson, Robert; Ellensen, Vegard Skalstad; Haaverstad, Rune; Holzapfel, Gerhard; Skallerud, Bjørn Helge; Prot, Victorien Emile (Journal article; Peer reviewed, 2023)
      Degenerative mitral valve disease is the main cause of primary mitral regurgitation with two phenotypes: fibroelastic deficiency (FED) often with localized myxomatous degeneration and diffuse myxomatous degeneration or ...
    • Mitral annular dynamics are influenced by left ventricular load and contractility in an acute animal model 

      Persson, Robert Matongo; Aguilera, Hans Martin Dahl; Kvitting, Jon Peder Escobar; Grong, Ketil; Prot, Victorien Emile; Salminen, Pirjo-Riitta; Svenheim, Bård; Leiknes, Anita; Stangeland, Lodve; Haaverstad, Rune; Urheim, Stig (Journal article; Peer reviewed, 2023)
      The purpose of this study was to investigate the effects of loading conditions and left ventricular (LV) contractility on mitral annular dynamics. In 10 anesthetized pigs, eight piezoelectric transducers were implanted ...