Blar i Bergen Open Research Archive på forfatter "Ryu, Hwayeon"
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Bifurcation and sensitivity analysis reveal key drivers of multistability in a model of macrophage polarization
Frank, Anna-Simone; Larripa, Kamila; Ryu, Hwayeon; Snodgrass, Ryan; Röblitz, Susanna (Journal article; Peer reviewed, 2020)In this paper, we present and analyze a mathematical model for polarization of a single macrophage which, despite its simplicity, exhibits complex dynamics in terms of multistability. In particular, we demonstrate that an ... -
Macrophage phenotype transitions in a stochastic gene-regulatory network model
Frank, Anna-Simone Josefine; Larripa, Kamila; Ryu, Hwayeon; Röblitz, Susanna (Journal article; Peer reviewed, 2023)Polarization is the process by which a macrophage cell commits to a phenotype based on external signal stimulation. To know how this process is affected by random fluctuations and events within a cell is of utmost importance ...