Blar i Bergen Open Research Archive på forfatter "Vydra, Natalia"

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    • Crosstalk between HSF1 and HSF2 during the heat shock response in mouse testes 

      Korfanty, Joanna; Stokowy, Tomasz; Widlak, Piotr; Gogler-Piglowska, Agnieszka; Handschuh, Luiza; Podkowinski, Jan; Vydra, Natalia; Naumowicz, Anna; Toma-Jonik, Agnieszka; Widlak, Wieslawa (Peer reviewed; Journal article, 2014-12)
      Heat Shock Factor 1 (HSF1) is the primary transcription factor responsible for the response to cellularstress, while HSF2 becomes activated during development and differentiation, including spermatogen-esis. Although both ...

    • Heat shock factor 1 (Hsf1) cooperates with estrogen receptor α (erα) in the regulation of estrogen action in breast cancer cells 

      Vydra, Natalia; Janus, Patryk; Kuś, Paweł; Stokowy, Tomasz; Mrowiec, Katarzyna; Toma-Jonik, Agnieszka; Krzywon, Aleksandra; Cortez, Alexander Jorge; Wojtaś, Bartosz; Gielniewski, Bartłomiej; Jaksik, Roman; Kimmel, Marek; Widłak, Wiesława (Journal article; Peer reviewed, 2021)
      Heat shock factor 1 (HSF1), a key regulator of transcriptional responses to proteotoxic stress, was linked to estrogen (E2) signaling through estrogen receptor α (ERα). We found that an HSF1 deficiency may decrease ERα ...

    • HSF1 Can Prevent Inflammation following Heat Shock by Inhibiting the Excessive Activation of the ATF3 and JUN&FOS Genes 

      Janus, Patryk; Kuś, Paweł; Vydra, Natalia; Toma-Jonik, Agnieszka; Stokowy, Tomasz; Mrowiec, Katarzyna; Wojtaś, Bartosz; Gielniewski, Bartłomiej; Widłak, Wiesława (Journal article; Peer reviewed, 2022)
      Heat Shock Factor 1 (HSF1), a transcription factor frequently overexpressed in cancer, is activated by proteotoxic agents and participates in the regulation of cellular stress response. To investigate how HSF1 level affects ...

    • An Increase in HSF1 Expression Directs Human Mammary Epithelial Cells toward a Mesenchymal Phenotype 

      Vydra, Natalia; Toma-Jonik, Agnieszka; Janus, Patryk; Mrowiec, Katarzyna; Stokowy, Tomasz; Głowala-Kosińska, Magdalena; Sojka, Damian Robert; Olbryt, Magdalena; Widłak, Wiesława (Journal article; Peer reviewed, 2023)
      HSF1 is a well-known heat shock protein expression regulator in response to stress. It also regulates processes important for growth, development or tumorigenesis. We studied the HSF1 influence on the phenotype of ...