• BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma 

      Wang, Jiwei; Chen, Anbin; Xue, Zhiwei; Liu, Junzhi; He, Ying; Liu, Guowei; Zhao, Zhimin; Li, Wenjie; Zhang, Qing; Chen, Anjing; Wang, Jian; Li, Xingang; Wang, Xinyu; Huang, Bin (Journal article; Peer reviewed, 2023)
      There is an urgent need for novel diagnostic and therapeutic strategies for patients with Glioblastoma multiforme (GBM). Previous studies have shown that BCL2 like 13 (BCL2L13) is a member of the BCL2 family regulating ...
    • Comprehensive analysis of PSMD family members and validation of PSMD9 as a potential therapeutic target in human glioblastoma 

      Li, Yaquan; Liu, Xuemeng; Zhao, Feihu; Zhao, Zhimin; Li, Xingang; Wang, Jian; Huang, Bin; Chen, Anjing (Journal article; Peer reviewed, 2023)
      Aims PSMD family members, as important components of the 26S proteasome, are well known to be involved in protein degradation. However, their role in glioblastoma (GBM) has not been rigorously investigated. We aimed to ...
    • Identification of immune-related genes contributing to the development of glioblastoma using weighted gene co-expression network analysis 

      Kong, Yang; Feng, Zichao; Zhang, Yulin; Liu, Xiaofei; Ma, Yuan; Zhao, Zhimin; Huang, Bin; Chen, An-Jing; Zhang, Di; Thorsen, Frits; Wang, Jian; Yang, Ning; Li, Xingang (Journal article; Peer reviewed, 2020)
      Background: The tumor microenvironment (TME) of human glioblastoma (GBM) exhibits considerable immune cell infiltration, and such cell types have been shown to be widely involved in the development of GBM. Here, weighted ...
    • Loss of COPZ1 induces NCOA4 mediated autophagy and ferroptosis in glioblastoma cell lines 

      Zhang, Yulin; Kong, Yang; Ma, Yuan; Ni, Shilei; Wikerholmen, Tobias Espedal; Xi, Kaiyan; Zhao, Feihu; Zhao, Zhimin; Wang, Junpeng; Huang, Bin; Chen, Anjing; Yao, Zhong; Han, Mingzhi; Feng, Zichao; Hu, Yaotian; Thorsen, Frits; Wang, Jiang; Li, Xingang (Journal article; Peer reviewed, 2021)
      Dysregulated iron metabolism is a hallmark of many cancers, including glioblastoma (GBM). However, its role in tumor progression remains unclear. Herein, we identified coatomer protein complex subunit zeta 1 (COPZ1) as a ...