• B-vitamin Treatment Modifies the Mortality Risk Associated with Calcium Channel Blockers in Patients with Suspected Stable Angina Pectoris: A Prospective Cohort Study 

      Dhar, Indu; Svingen, Gard Frodahl Tveitevåg; Bjørnestad, Espen Øglænd; Ulvik, Arve; Saeed, Sahrai; Nygård, Ottar Kjell (Journal article; Peer reviewed, 2023)
      Background Calcium channel blockers (CCBs) are used for the treatment of cardiovascular disease (CVD), including angina pectoris, and hypertension; however, the effect on survival remains uncertain. CCBs impair fibrinolysis ...
    • Circulating concentrations of biomarkers and metabolites related to Vitamin status, one-carbon and the kynurenine pathways in US, Nordic, Asian, and Australian populations 

      Midttun, Øivind; Theofylaktopoulou, Despoina; Mccann, Adrian; Fanidi, Anouar; Muller, David C.; Meyer, Klaus; Ulvik, Arve; Zheng, Wei; Shu, Xiao-Ou; Xiang, Yong-Bing; Prentice, Ross; Thomson, Cynthia A.; Pettinger, Mary; Giles, Graham G.; Hodge, Allison; Cai, Qiuyin; Blot, William J.; Wu, Jie; Johansson, Mikael; Hultdin, Johan; Grankvist, Kjell; Stevens, Victoria L.; McCullough, Marjorie L.; Weinstein, Stephanie J.; Albanes, Demetrius; Langhammer, Arnulf; Hveem, Kristian; Næss, Marit; Sesso, Howard D.; Gaziano, J. Michael; Buring, Julie E.; Lee, I-Min; Severi, Gianluca; Zhang, Xuehong; Han, Jiali; Stampfer, Meir J.; Smith-Warner, Stephanie A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loic; Yuan, Jian-Min; Butler, Lesley M.; Koh, Woon-Puay; Wang, Renwei; Gao, Yu-Tang; Ericson, Ulrika; Sonestedt, Emily; Ziegler, Regina G.; Freedman, Neal D.; Visvanathan, Kala; Jones, Miranda R.; Relton, Caroline; Brennan, Paul; Johansson, Mattias; Ueland, Per Magne (Peer reviewed; Journal article, 2017-06)
      Background: Circulating concentrations of biomarkers that are related to vitamin status vary by factors such as diet, fortification, and supplement use. Published biomarker concentrations have also been influenced by the ...
    • A comparison of complementary measures of vitamin B6 status, function, and metabolism in the European Prospective Investigation into Cancer and Nutrition (EPIC) study 

      Clasen, Joanna L; Heath, Alicia K.; Van Puyvelde, Heleen; Huybrechts, Inge; Park, Jin Young; Ferrari, Pietro; Johansson, Mattias; Scelo, Ghislaine; Ulvik, Arve; Midttun, Øivind; Ueland, Per Magne; Dahm, Christina C; Halkjær, Jytte; Olsen, Anja; Johnson, Theron; Katzke, Verena; Schulze, Matthias B; Masala, Giovanna; Segrado, Francesco; De Magistris, Maria Santucci; Sacerdote, Carlotta; Ocké, Marga C; Luján-Barroso, Leila; Ching-López, Ana; Huerta, José María; Ardanaz, Eva; Amiano, Pilar; Ericson, Ulrika; Manjer, Jonas; Gylling, Björn; Johansson, Ingegerd; Schmidt, Julie; Weiderpass, Elisabete; Riboli, Elio; Cross, Amanda J; Muller, David C (Journal article; Peer reviewed, 2021)
      Background Vitamin B6 insufficiency has been linked to increased risk of cancer and other chronic diseases. The circulating concentration of pyridoxal 5′-phosphate (PLP) is a commonly used measure of vitamin B6 status. ...
    • Does maternal genetic liability to folate deficiency influence the risk of antiseizure medication-associated language impairment and autistic traits in children of women with epilepsy? 

      Husebye, Elisabeth Synnøve Nilsen; Romanowska, Julia; Monsen, Anne-Lise Bjørke; Gilhus, Nils Erik; Selmer, Kaja Kristine; Gervin, Kristina; Riedel, Bettina Maria Ingeborg; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2023)
      Background: Prenatal exposure to antiseizure medication (ASM) may lead to low plasma folate concentrations and is associated with impaired neurodevelopment. Objectives: To examine whether maternal genetic liability to ...
    • Elevated plasma cystathionine is associated with increased risk of mortality among patients with suspected or established coronary heart disease 

      Dhar, Indu; Lysne, Vegard; Svingen, Gard Frodahl Tveitevåg; Ueland, Per Magne; Gregory, Jesse F.; Bønaa, Kaare Harald; Nygård, Ottar (Journal article; Peer reviewed, 2019)
      Background Elevated circulating cystathionine levels are related to atherosclerotic cardiovascular disease, a leading cause of death globally. Objective We investigated whether plasma cystathionine was associated with ...
    • Full breastfeeding protection against common enteric bacteria and viruses: Results from the MAL-ED cohort study 

      Mccormick, Benjamin J. J; Richard, Stephanie A; Murray-Kolb, Laura E; Kang, Gagandeep; Lima, Aldo A. M; Mduma, Estomih; Kosek, Margaret N; Rogawski Mcquade, Elizabeth T; Houpt, Eric R; Bessong, Pascal; Shrestha, Sanjaya; Bhutta, Zulfiqar; Ahmed, Tahmeed; Caulfield, Laura E; Acosta, Angel Mendez; De Burga, Rosa Rios; Chavez, Cesar Banda; Flores, Julian Torres; Olotegui, Maribel Paredes; Pinedo, Silvia Rengifo; Salas, Mery Siguas; Trigoso, Dixner Rengifo; Vasquez, Angel Orbe; Ahmed, Imran; Alam, Didar; Ali, Asad; Bhutta, Zulfiqar A.; Qureshi, Shahida; Rasheed, Muneera Abdul; Soofi, Sajid; Turab, Ali; Yousafzai, Aisha; Zaidi, Anita K. M.; Bodhidatta, Ladaporn; Ammu, Geetha; Babji, Sudhir; Bose, Anuradha; George, Ajila T.; Hariraju, Dinesh; Jennifer, M Steffi; John, Sushil; Kaki, Shiny; Karunakaran, Priyadarshani; Koshy, Beena; Lazarus, Robin P.; Muliyil, Jayaprakash; Ragasudha, Preethi; Raghava, Mohan Venkata; Raju, Sophy; Ramachandran, Anup; Ramadas, Rakhi; Ramanujam, Karthikeyan; Rose, Anuradha; Roshan, Reeba; Sharma, Srujan L.; Shanmuga Sundaram, Sundaram; Thomas, Rahul J.; Pan, William K.; Ambikapathi, Ramya; Carreon, J. Daniel; Doan, Viyada; Hoest, Christel; Knobler, Stacey; McCormick, Benjamin J. J.; McGrath, Monica; Miller, Mark A.; Psaki, Stephanie; Rasmussen, Zeba; Seidman, Jessica C.; Gottlieb, Michael; Lang, Dennis R.; Tountas, Karen H.; Svensen, Erling; Amour, Caroline; Bayyo, Eliwaza; Mduma, Estomih R.; Mvungi, Regisiana; Nshama, Rosemary; Pascal, John; Swema, Buliga Mujaga; Yarrot, Ladislaus; Mason, Carl J.; Shamsir Ahmed, Ahmed; Alam, Md Ashraful; Haque, Rashidul; Haque, Umma; Hossain, Md Iqbal; Islam, Munirul; Mahfuz, Mustafa; Mondal, Dinesh; Nahar, Baitun; Tofail, Fahmida; Chandyo, Ram Krishna; Shrestha, Prakash Sunder; Shrestha, Rita; Chandyo, Manjeswori Ulak; Bauck, Aubrey; Black, Robert E.; Checkley, William; Lee, Gwenyth O.; Schulze, Kerry; Yori, Pablo Peñataro; Ross, A. Catharine; Schaefer, Barbara; Simons, Suzanne; Pendergast, Laura; Abreu, Cláudia B.; Costa, Hilda; Di Moura, Alessandra; Filho, José Quirino; Havt, Alexandre; Leite, Álvaro M.; Lima, Noélia L.; Lima, Ila F.; Maciel, Bruna L. L.; Medeiros, Pedro H. Q. S.; Moraes, Milena; Mota, Francisco S.; Oriá, Reinaldo B.; Quetz, Josiane; Soares, Alberto M.; Mota, Rosa M. S.; Patil, Crystal L.; Mahopo, Cloupas; Maphula, Angelina; Nyathi, Emanuel; Samie, Amidou; Barrett, Leah; Dillingham, Rebecca; Gratz, Jean; Guerrant, Richard L.; Houpt, Eric; Petri, William A.; Platts-Mills, James; Rogawski, Elizabeth; Scharf, Rebecca; Rogawski, Elizabeth T.; Shrestha, Binob; Rayamajhi, Bishnu Bahadur; Strand, Tor Arne (Journal article; Peer reviewed, 2022)
      Background Breastfeeding is known to reduce the risk of enteropathogen infections, but protection from specific enteropathogens is not well characterized. Objective The aim was to estimate the association between full ...
    • The PAr index, an indicator reflecting altered vitamin B-6 homeostasis, is associated with long-term risk of stroke in the general population: the Hordaland Health Study (HUSK) 

      Zuo, Hui; Tell, Grethe S.; Ueland, Per Magne; Nygård, Ottar; Vollset, Stein Emil; Midttun, Øivind; Meyer, Klaus; Ulvik, Arve (Peer reviewed; Journal article, 2018-01)
      Background: Vitamin B-6 homeostasis is altered during inflammation and immune activation. It is unknown whether altered vitamin B-6 homeostasis is associated with the risk of stroke. Objective: We investigated the relation ...
    • Plasma unmetabolized folic acid in pregnancy and risk of autistic traits and language impairment in antiseizure medication-exposed children of women with epilepsy 

      Husebye, Elisabeth Synnøve Nilsen; Wendel, Annabel Willemijn Karine; Gilhus, Nils Erik; Riedel, Bettina Maria Ingeborg; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)
      Background: Fetal exposure to unmetabolized folic acid (UMFA) during pregnancy may be associated with adverse neurodevelopment. Antiseizure medication (ASM) may interact with folate metabolism. Women with epilepsy using ...
    • Tryptophan catabolites as metabolic markers of vitamin B-6 status evaluated in cohorts of healthy adults and cardiovascular patients 

      Ulvik, Arve; Midttun, Øivind; McCann, Adrian; Meyer, Klaus; Tell, Grethe S.; Nygård, Ottar; Ueland, Per Magne (Journal article; Peer reviewed, 2020)
      Background Vitamin B-6 status is routinely measured as pyridoxal 5′-phosphate (PLP) in plasma. Low concentrations of PLP are associated with rheumatic, cardiovascular, and neoplastic diseases. We have previously shown ...
    • Using metabolic profiling and gene expression analyses to explore molecular effects of replacing saturated fat with polyunsaturated fat-a randomized controlled dietary intervention study 

      Ulven, Stine Marie; Christensen, Jacob J.; Nygård, Ottar; Svardal, Asbjørn M.; Leder, Lena; Ottestad, Inger; Lysne, Vegard; Laupsa-Borge, Johnny; Ueland, Per Magne; Midttun, Øivind; Meyer, Klaus; McCann, Adrian; Andersen, Lene Frost; Holven, Kirsten Bjørklund (Peer reviewed; Journal article, 2019-04-26)
      Background: Replacing dietary saturated fatty acids (SFAs) with polyunsaturated fatty acids (PUFA) reduces the plasma low-density lipoprotein (LDL) cholesterol and subsequently the risk of cardiovascular disease. However, ...