Blar i Bergen Open Research Archive på tidsskrift "Cell Death & Disease"

Viser treff 1-2 av 2

    • Anti-proliferative activity of the NPM1 interacting natural product avrainvillamide in acute myeloid leukemia 

      Andresen, Vibeke; Erikstein, Bjarte Skoe; Mukherjee, Herschel; Sulen, Andre; Popa, Mihaela Lucia; Sørnes, Steinar; Reikvam, Håkon; Chan, Kok-Ping; Hovland, Randi; McCormack, Emmet; Bruserud, Øystein; Myers, Andrew G.; Gjertsen, Bjørn Tore (Peer reviewed; Journal article, 2016-12-01)
      Mutated nucleophosmin 1 (NPM1) acts as a proto-oncogene and is present in ~30% of patients with acute myeloid leukemia (AML). Here we examined the in vitro and in vivo anti-leukemic activity of the NPM1 and chromosome ...

    • The dual role of glioma exosomal microRNAs: glioma eliminates tumor suppressor miR-1298-5p via exosomes to promote immunosuppressive effects of MDSCs 

      Qi, Yanhua; Jin, Chuandi; Qiu, Wei; Zhao, Rongrong; Wang, Shaobo; Li, Boyan; Zhang, Zongpu; Guo, Qindong; Zhang, Shouji; Gao, Zijie; Zhao, Shulin; Pan, Ziwen; Fan, Yang; chen, Zihang; Wang, Huizhi; Xu, Jianye; Deng, Lin; Ni, Shilei; Wang, Jian; Xue, Hao; Xue, Fuzhong; Li, Gang (Journal article; Peer reviewed, 2022)
      Clear evidence shows that tumors could secrete microRNAs (miRNAs) via exosomes to modulate the tumor microenvironment (TME). However, the mechanisms sorting specific miRNAs into exosomes are still unclear. In order to study ...