• Abrupt high-latitude climate events and decoupled seasonal trends during the Eemian 

      Salonen, J. Sakari; Helmens, Karin F.; Brendryen, Jo; Kuosmanen, Niina; Väliranta, Minna; Goring, Simon; Korpela, Mikko; Kylander, Malin; Philip, Annemarie; Plikk, Anna; Renssen, Hans; Luoto, Miska (Peer reviewed; Journal article, 2018-07-20)
      The Eemian (the Last Interglacial; ca. 129–116 thousand years ago) presents a testbed for assessing environmental responses and climate feedbacks under warmer-than-present boundary conditions. However, climate syntheses ...
    • Asynchronous Antarctic and Greenland ice-volume contributions to the last interglacial sea-level highstand 

      Rohling, E.J.; Hibbert, F.D.; Grant, K.M.; Galaasen, Eirik Vinje; Irvali, Nil; Kleiven, Helga Flesche; Marino, G.; Ninnemann, Ulysses S; Roberts, A.P.; Rosenthal, Y.; Schulz, H.; Williams, F.H.; Yu, J. (Peer reviewed; Journal article, 2019-11-06)
      The last interglacial (LIG; ~130 to ~118 thousand years ago, ka) was the last time global sea level rose well above the present level. Greenland Ice Sheet (GrIS) contributions were insufficient to explain the highstand, ...
    • Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation 

      Frei, Oleksandr; Holland, Dominic; Smeland, Olav Bjerkehagen; Shadrin, Alexey A.; Fan, Chun Chieh; Maeland, Steffen; O'Connell, Kevin S.; Wang, Yunpeng; Djurovic, Srdjan; Thompson, Wesley Kurt; Andreassen, Ole Andreas; Dale, Anders (Peer reviewed; Journal article, 2019-06-03)
      Accumulating evidence from genome wide association studies (GWAS) suggests an abundance of shared genetic influences among complex human traits and disorders, such as mental disorders. Here we introduce a statistical tool, ...
    • Deciphering the complex role of thrombospondin-1 in glioblastoma development 

      Daubon, Thomas; Léon, Céline; Clarke, Kim; Andrique, Laetitia; Salabert, Laura; Darbo, Elodie; Pineau, Raphael; Guérit, Sylvaine; Maitre, Marlène; Dedieu, Stéphane; Jeanne, Albin; Bailly, Sabine; Feige, Jean-Jacques; Miletic, Hrvoje; Rossi, Marco; Bello, Lorenzo; Falciani, Francesco; Bjerkvig, Rolf; Bikfalvi, Andréas (Peer reviewed; Journal article, 2019-03-08)
      We undertook a systematic study focused on the matricellular protein Thrombospondin-1 (THBS1) to uncover molecular mechanisms underlying the role of THBS1 in glioblastoma (GBM) development. THBS1 was found to be increased ...
    • Deep 2-photon imaging and artifact-free optogenetics through transparent graphene microelectrode arrays 

      Thunemann, Martin; Lu, Yichen; Liu, Xin; Kılıç, Kıvılcım; Desjardins, Michèle; Vandenberghe, Matthieu; Sadegh, Sanaz; Saisan, Payam A.; Cheng, Qun; Weldy, Kimberly L.; Lyu, Hongming; Djurovic, Srdjan; Andreassen, Ole Andreas; Dale, Anders; Devor, Anna; Kuzum, Duygu (Peer reviewed; Journal article, 2018-05-23)
      Recent advances in optical technologies such as multi-photon microscopy and optogenetics have revolutionized our ability to record and manipulate neuronal activity. Combining optical techniques with electrical recordings ...
    • Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease 

      Dölle, Christian; Flønes, Irene Hana; Sanchez Nido, Gonzalo; Miletic, Hrvoje; Osuagwu, Nelson; Kristoffersen, Stine; Lilleng, Peer Kåre; Larsen, Jan Petter; Tysnes, Ole-Bjørn; Haugarvoll, Kristoffer; Bindoff, Laurence; Tzoulis, Charalampos (Peer reviewed; Journal article, 2016-11-22)
      Increased somatic mitochondrial DNA (mtDNA) mutagenesis causes premature aging in mice, and mtDNA damage accumulates in the human brain with aging and neurodegenerative disorders such as Parkinson disease (PD). Here, we ...
    • The genetic architecture of human brainstem structures and their involvement in common brain disorders 

      Elvsåshagen, Torbjørn; Bahrami, Shahram; van der Meer, Dennis; Agartz, Ingrid; Alnæs, Dag; Barch, Deanna M.; Baur-Streubel, Ramona; Bertolino, Alessandro; Beyer, Mona K.; Blasi, Giuseppe; Borgwardt, Stefan; Boye, Birgitte; Buitelaar, Jan; Bøen, Erlend; Celius, Elisabeth Gulowsen; Cervenka, Simon; Conzelmann, Annette; Coynel, David; di Carlo, Pasquale; Djurovic, Srdjan; Eisenacher, Sarah; Espeseth, Thomas; Fatouros-Bergman, Helena; Flyckt, Lena; Franke, Barbara; Frei, Oleksandr; Gelao, Barbara; Harbo, Hanne Flinstad; Hartman, Catharina A.; Håberg, Asta; Heslenfeld, Dirk; Hoekstra, Pieter J.; Høgestøl, Einar August; Jonassen, Rune; Jönsson, Erik G.; Kirsch, Peter; Kloszewska, Iwona; Lagerberg, Trine Vik; Landrø, Nils Inge; Le Hellard, Stephanie; Lesch, Klaus-Peter; Maglanoc, Luigi Angelo; Malt, Ulrik Fredrik; Mecocci, Patrizia; Melle, Ingrid; Meyer-Lindenberg, Andreas; Moberget, Torgeir; Nordvik, Jan Egil; Nyberg, Lars; O’ Connell, Kevin S.; Oosterlaan, Jaap; Papalino, Marco; Papassotiropoulos, Andreas; Pauli, Paul; Pergola, Giulio; Persson, Karin; de Quervain, Dominique; Reif, Andreas; Rokicki, Jaroslav; Van Rooij, Daan; Shadrin, Alexey A.; Schmidt, André; Schwarz, Emanuel; Selbæk, Geir; Soininen, Hilkka; Sowa, Piotr; Steen, Vidar M.; Tsolaki, Magda; Vellas, Bruno; Wang, Lei; Westman, Eric; Ziegler, Georg C.; Zink, Mathias; Andreassen, Ole Andreas; Westlye, Lars Tjelta; Kaufmann, Tobias (Journal article, 2020)
      Brainstem regions support vital bodily functions, yet their genetic architectures and involvement in common brain disorders remain understudied. Here, using imaging-genetics data from a discovery sample of 27,034 individuals, ...
    • Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth 

      Helgeland, Øyvind; Vaudel, Marc; Juliusson, Petur Benedikt; Holmen, Oddgeir Lingaas; Juodakis, Julius; Bacelis, Jonas; Jacobsson, Bo; Lindekleiv, Haakon; Hveem, Kristian; Lie, Rolv T.; Knudsen, Gun Peggy Strømstad; Stoltenberg, Camilla; Magnus, Per; Sagen, Jørn V.; Molven, Anders; Johansson, Stefan; Njølstad, Pål Rasmus (Peer reviewed; Journal article, 2019-10-01)
      Infant and childhood growth are dynamic processes with large changes in BMI during development. By performing genome-wide association studies of BMI at 12 time points from birth to eight years (9286 children, 74,105 ...
    • GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis 

      Cabral-Marques, Otavio; Marques, Alexandre; Melvær, Giil Lasse; De Vito, Roberta; Rademacher, Judith; Günther, Jeannine; Lange, Tanja; Humrich, Jens; Klapa, Sebastian; Schinke, Susanne; Schimke, Lena; Marschner, Gabriele; Pitann, Silke; Adler, Sabine; Dechend, Ralf; Muller, Dominik N.; Braicu, Ioana; Sehouli, Jalid; Schulze-Forster, Kai; Trippel, Tobias; Scheibenbogen, Carmen; Staff, Anne Cathrine; Mertens, Peter; Löbel, Madlen; Mastroianni, Justin; Plattfaut, Corinna; Gieseler, Frank; Dragun, Duska; Engelhardt, Barbara Elizabeth; Fernandez-Cabezudo, Maria; Ochs, Hans D; Al-Ramadi, Basel K; Lamprecht, Peter; Mueller, Antje; Heidecke, Harald; Riemekasten, Gabriela (Peer reviewed; Journal article, 2018-12-06)
      Autoantibodies have been associated with autoimmune diseases. However, studies have identified autoantibodies in healthy donors (HD) who do not develop autoimmune disorders. Here we provide evidence of a network of ...
    • Identification of nine new susceptibility loci for endometrial cancer 

      O'Mara, Tracy A.; Glubb, Dylan M.; Amant, Frédéric; Annibali, Daniela; Ashton, Katie; Attia, John; Auer, Paul L.; Beckmann, Matthias W.; Black, Amanda; Bolla, Manjeet K.; Brauch, Hiltrud; Brenner, Hermann; Brinton, Louise; Buchanan, Daniel D.; Burwinkel, Barbara; Chang-Claude, Jenny; Chanock, Stephen J.; Chen, Chu; Chen, Maxine M.; Cheng, Timothy H.T.; Clarke, Christine L.; Clendenning, Mark; Cook, Linda S.; Couch, Fergus J.; Cox, Angela; Crous-Bous, Marta; Czene, Kamila; Day, Felix; Dennis, Joe; Depreeuw, Jeroen; Doherty, Jennifer Anne; Dörk, Thilo; Dowdy, Sean C.; Dürst, Matthias; Ekici, Arif B.; Fasching, Peter A.; Fridley, Brooke L.; Friedenreich, Christine M.; Fritschi, Lin; Fung, Jenny; García-Closas, Montserrat; Gaudet, Mia M.; Giles, Graham G.; Goode, Ellen L.; Gorman, Maggie; Haiman, Christopher A.; Hall, Per; Hankison, Susan E.; Healey, Catherine S.; Hein, Alexander; Hillemanns, Peter; Hodgson, Shirley; Høivik, Erling Andre; Holliday, Elizabeth G.; Hopper, John L.; Hunter, David J.; Jones, Angela; Krakstad, Camilla; Kristensen, Vessela N.; Lambrechts, Diether; Marchand, Loic Le; Liang, Xiaolin; Lindblom, Annika; Lissowska, Jolanta; Long, Jirong; Lu, Lingeng; Magliocco, Anthony M.; Martin, Lynn; McEvoy, Mark; Meindl, Alfons; Michailidou, Kyriaki; Milne, Roger L.; Mints, Miriam; Montgomery, Grant W.; Nassir, Rami; Olsson, Håkan; Orlow, Irene; Otton, Geoffrey; Palles, Claire; Perry, John R.B.; Peto, Julian; Pooler, Loreall; Prescott, Jennifer; Proietto, Tony; Rebbeck, Timothy R.; Risch, Harvey A.; Rogers, Peter A.W.; Rübner, Matthias; Runnebaum, Ingo; Sacerdote, Carlotta; Sarto, Gloria E.; Schumacher, Fredrick; Scott, Rodney J.; Setiawan, V. Wendy; Shah, Mitul; Sheng, Xin; Shu, Xiao-Ou; Southey, Melissa C.; Swerdlow, Anthony J.; Tham, Emma; Trovik, Jone; Turman, Constance; Tyrer, Jonathan P.; Vachon, Celine; VanDen Berg, David; Vanderstichele, Adriaan; Wang, Zhaoming; Webb, Penelope M.; Wentzensen, Nicolas; Werner, Henrica Maria Johanna; Winham, Stacey J.; Wolk, Alicja; Xia, Lucy; Xiang, Yong-Bing; Yang, Hannah P.; Yu, Herbert; Zheng, Wei; Pharoah, Paul D.P.; Dunning, Alison M.; Kraft, Peter; De Vivo, Immaculata; Tomlinson, Ian; Easton, Douglas F.; Spurdle, Amanda B.; Thompson, Deborah J. (Peer reviewed; Journal article, 2018-08-09)
      Endometrial cancer is the most commonly diagnosed cancer of the female reproductive tract in developed countries. Through genome-wide association studies (GWAS), we have previously identified eight risk loci for endometrial ...
    • Identification of susceptibility pathways for the roleof chromosome 15q25.1 in modifying lung cancerrisk 

      Ji, Xuemei; Bossé, Yohan; Landi, Maria Teresa; Gui, Jiang; Xiao, Xiangjun; Qian, David C; Joubert, Philippe; Lamontagne, Maxime; Li, Yafang; Gorlov, Ivan; de Biasi, Mariella; Han, Younghun; Gorlova, Olga; Hung, Rayjean J.; Wu, Xifeng; McKay, James; Zong, Xuchen; Carreras-Torres, Robert; Christiani, David C.; Caporaso, Neil; Johansson, Mattias; Liu, Geoffrey; Bojesen, Stig E.; Le Marchand, Loic; Albanes, Demetrios; Bickeboller, Heike; Aldrich, Melinda C.; Bush, William S.; Tardon, Adonina; Rennert, Gad; Chen, Chu; Teare, M. Dawn; Field, John K.; Kiemeney, Lambertus A.; Lazarus, Philip; Haugen, Aage; Lam, Stephen; Schabath, Matthew B.; Andrew, Angeline S.; Shen, Hongbing; Hong, Yun-Chul; Yuan, Jian-Min; Bertazzi, Pier A.; Pesatori, Angela C.; Ye, Yuanqing; Diao, Nancy; Su, Li; Zhang, Ruyang; Brhane, Yonathan; Leighl, Natasha; Johansen, Jakob S.; Mellemgaard, Anders; Saliba, Walid; Haiman, Christopher; Wilkens, Lynne; Fernandez-Somoano, Ana; Fernandez-Tardon, Guillermo; van der Heijden, Erik H. F. M.; Kim, Jin Hee; Dai, Juncheng; Hu, Zhibin; Davies, Michael P.A.; Marcus, Michael W.; Brunnström, Hans; Manjer, Jonas; Melander, Olle; Muller, David C.; Overvad, Kim; Trichopoulou, Antonia; Tumino, Rosario; Doherty, Jennifer; Goodman, Gary; Cox, Angela; Taylor, Fiona; Woll, Penella; Brüske, Irene; Manz, Judith; Muley, Thomas; Risch, Angela; Rosenberger, Albert; Grankvist, Kjell; Johansson, Mikael; Shepherd, Frances; Ming-Sound, Tsao; Arnold, Susanne M.; Haura, Eric B.; Bolca, Ciprian; Holcatova, Ivana; Janout, Vladimir; Kontic, Milica; Lissowska, Jolanta; Mukeria, Anush; Ognjanovic, Simona; Orlowski, Tadeusz M.; Scelo, Ghislaine; Swiatkowska, Beata; Zaridze, David; Bakke, Per S.; Skaug, Vidar; Zienolddiny, Shanbeh; Duell, Eric J.; Butler, Lesley M.; Koh, Woon-Puay; Gao, Yu-Tang; Houlston, Richard; McLaughlin, John; Stevens, Victoria; Nickle, David C.; Obeidat, Ma'en; Timens, Wim; Zhu, Bin; Song, Lei; Artigas, María Soler; Tobin, Martin D.; Wain, Louise V.; Gu, Fangyi; Byun, Jinyoung; Kamal, Ahsan; Zhu, Dakai; Tyndale, Rachel F.; Wei, Wei-Qi; Chanock, Stephen; Brennan, Paul; Amos, Christopher I. (Peer reviewed; Journal article, 2018-08-13)
      Genome-wide association studies (GWAS) identified the chromosome 15q25.1 locus as a leading susceptibility region for lung cancer. However, the pathogenic pathways, through which susceptibility SNPs within chromosome 15q25.1 ...
    • An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment 

      Tekpli, Xavier; Lien, Tonje Gulbrandsen; Røssevold, Andreas Hagen; Nebdal, Daniel J.H.; Borgen, Elin; Ohnstad, Hege Oma; Kyte, Jon A; Vallon-Christersson, Johan; Fongaard, Marie; Due, Eldri Undlien; Svartdal, Lisa Gregusson; Sveli, My Anh Tu; Garred, Øystein; Frigessi Di Rattalma, Arnoldo; Sahlberg, Kristine Kleivi; Sørlie, Therese; Russnes, Hege Elisabeth Giercksky; Naume, Bjørn; Kristensen, Vessela N. (Peer reviewed; Journal article, 2019)
      How mixtures of immune cells associate with cancer cell phenotype and affect pathogenesis is still unclear. In 15 breast cancer gene expression datasets, we invariably identify three clusters of patients with gradual levels ...
    • Irminger Sea deep convection injects oxygen and anthropogenic carbon to the ocean interior 

      Fröb, Friederike; Olsen, A.; Våge, K.; Moore, G.W.K; Yashayaev, I. (Peer reviewed; Journal article, 2016-10-27)
      Deep convection in the subpolar North Atlantic ventilates the ocean for atmospheric gases through the formation of deep water masses. Variability in the intensity of deep convection is believed to have caused large variations ...
    • Large mesopelagic fishes biomass and trophic efficiency in the open ocean 

      Irigoien, Xabier; Klevjer, Thor A.; Røstad, Anders; Martinez, U.; Boyra, G.; Acuna, J. L.; Bode, A.; Echevarria, F.; Gonzalez-Gordillo, J. I.; Hernández-León, Santiago; Augsti, S.; Aksnes, Dag Lorents; Duarte, C. M.; Kaartvedt, Stein (Peer reviewed; Journal article, 2014-02-07)
      With a current estimate of ~1,000 million tons, mesopelagic fishes likely dominate the world total fishes biomass. However, recent acoustic observations show that mesopelagic fishes biomass could be significantly larger ...
    • Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight 

      Küpers, Leanne K.; Monnereau, Claire; Sharp, Gemma C.; Yousefi, Paul; Salas, Lucas A.; Ghantous, Akram; Page, Christian Magnus; Reese, Sarah E.; Wilcox, Allen J.; Czamara, Darina; Starling, Anne P.; Novoloaca, Alexei; Lent, Samantha; Roy, Ritu; Hoyo, Cathrine; Breton, Carrie V.; Allard, Catherine; Just, Allan C.; Bakulski, Kelly M.; Holloway, John W.; Everson, Todd M.; Xu, Cheng-Jian; Huang, Rae-Chi; van der Plaat, Diana A.; Wielscher, Matthias; Merid, Simon Kebede; Ullemar, Vilhelmina; Rezwan, Faisal I.; Lahti, Jari; van Dongen, Jenny; Langie, Sabine A.S.; Richardson, Tom G.; Magnus, Maria Christine; Nohr, Ellen A.; Xu, Zongli; Duijts, Liesbeth; Zhao, Shanshan; Zhang, Weiming; Plusquin, Michelle; DeMeo, Dawn L.; Solomon, Olivia; Heimovaara, Joosje H.; Jima, Dereje D.; Gao, Lu; Bustamante, Mariona; Perron, Patrice; Wright, Robert O.; Hertz-Picciotto, Irva; Zhang, Hongmei; Karagas, Margaret R.; Gehring, Ulrike; Marsit, Carmen J.; Beilin, Lawrence J.; Vonk, Judith M.; Jarvelin, Marjo-Riitta; Bergström, Anna; Örtqvist, Anne K.; Ewart, Susan; Villa, Pia M.; Moore, Sophie E.; Willemsen, Gonneke; Standaert, Arnout R.L.; Håberg, Siri Eldevik; Sørensen, Thorkild I.A.; Taylor, Jack A.; Räikkönen, Katri; Yang, Ivana V.; Kechris, Katerina; Nawrot, Tim S.; Silver, Matt J.; Gong, Yun Yun; Richiardi, Lorenzo; Kogevinas, Manolis; Litonjua, Augusto A.; Eskenazi, Brenda; Huen, Karen; Mbarek, Hamdi; Maguire, Rachel L.; Dwyer, Terence; Vrijheid, Martine; Bouchard, Luigi; Baccarelli, Andrea A.; Croen, Lisa A.; Karmaus, Wilfried; Anderson, Denise; de Vries, Maaike; Sebert, Sylvain; Kere, Juha; Karlsson, Robert; Arshad, Syed Hasan; Hämäläinen, Esa; Routledge, Michael N.; Boomsma, Dorret I.; Feinberg, Andrew P.; Newschaffer, Craig J.; Govarts, Eva; Moisse, Matthieu; Fallin, M. Daniele; Melén, Erik; Prentice, Andrew M.; Kajantie, Eero; Almqvist, Catarina; Oken, Emily; Dabelea, Dana; Boezen, H. Marike; Melton, Philip E.; Wright, Rosalind J.; Koppelman, Gerard H.; Trevisi, Letizia; Hivert, Marie-France; Sunyer, Jordi; Munthe-Kaas, Monica Cheng; Murphy, Susan K.; Corpeleijn, Eva; Wiemels, Joseph L.; Holland, Nina; Herceg, Zdenko; Binder, Elisabeth B.; Davey Smith, George; Jaddoe, Vincent V.W.; Lie, Rolv T.; Nystad, Wenche; London, Stephanie J.; Lawlor, Debbie A.; Relton, Caroline L.; Snieder, Harold; Felix, Janine F. (Peer reviewed; Journal article, 2019-04-23)
      Birthweight is associated with health outcomes across the life course, DNA methylation may be an underlying mechanism. In this meta-analysis of epigenome-wide association studies of 8,825 neonates from 24 birth cohorts in ...
    • A moiré deflectometer for antimatter 

      Aghion, Stefano; Ahlen, O; Amsler, C; Ariga, A; Ariga, T; Belov, AS; Berggren, K; Bonomi, G; Braunig, P; Bremer, J; Brusa, RS; Cabaret, L; Canali, C; Caravita, R; Castelli, F; Cerchiari, G; Cialdi, S; Comparat, D; Consolati, G; Derking, H; Di, Domizio,S; Di, Noto,L; Doser, M; Dudarev, A; Ereditato, A; Ferragut, R; Fontana, A; Genova, P; Giammarchi, M; Gligorova, Angela; Gninenko, SN; Haider, S; Huse, Torkjell; Jordan, E; Jorgensen, LV; Kaltenbacher, T; Kawada, J; Kellerbauer, A; Kimura, M; Knecht, A; Krasnicky, D; Lagomarsino, V; Lehner, S; Magnani, A; Malbrunot, C; Mariazzi, S; Matveev, VA; Moia, F; Nebbia, G; Nedelec, P; Oberthaler, MK; Pacifico, Nicola; Petracek, V; Pistillo, C; Prelz, F; Prevedelli, M; Regenfus, C; Riccardi, C; Røhne, Ole Myren; Rotondi, A; Sandaker, Heidi; Scampoli, P; Storey, J; Vasquez, MAS; Spacek, M; Testera, G; Vaccarone, R; Widmann, E; Zavatarelli, S; Zmeskal, J (Peer reviewed; Journal article, 2014-07-28)
      The precise measurement of forces is one way to obtain deep insight into the fundamental interactions present in nature. In the context of neutral antimatter, the gravitational interaction is of high interest, potentially ...
    • Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK 

      Deng, Sunbin; Mc Tiernan, Nina; Wei, Xuepeng; Arnesen, Thomas; Marmorstein, Ronen (Journal article; Peer reviewed, 2020-02)
      The human N-terminal acetyltransferase E (NatE) contains NAA10 and NAA50 catalytic, and NAA15 auxiliary subunits and associates with HYPK, a protein with intrinsic NAA10 inhibitory activity. NatE co-translationally acetylates ...
    • Ocean convection linked to the recent ice edge retreat along east Greenland 

      Våge, Kjetil; Papritz, Lukas; Håvik, Lisbeth; Spall, Michael A.; Moore, George William Kent (Peer reviewed; Journal article, 2018-03-29)
      Warm subtropical-origin Atlantic water flows northward across the Greenland-Scotland Ridge into the Nordic Seas, where it relinquishes heat to the atmosphere and gradually transforms into dense Atlantic-origin water. ...
    • Patterns of genomic evolution in advanced melanoma 

      Birkeland, Einar Elvbakken; Zhang, Shan; Poduval, Deepak; Geisler, Jürgen; Nakken, Sigve; Vodak, Daniel; Meza, Leonardo Zepeda; Hovig, Eivind; Myklebost, Ola; Knappskog, Stian; Lønning, Per Eystein (Peer reviewed; Journal article, 2018-07-10)
      Genomic alterations occurring during melanoma progression and the resulting genomic heterogeneity between metastatic deposits remain incompletely understood. Analyzing 86 metastatic melanoma deposits from 53 patients with ...
    • Position and orientation of the westerly jet determined Holocene rainfall patterns in China 

      Herzschuh, Ulrike; Cao, Xianyong; Laepple, Thomas; Dallmeyer, Anne; Telford, Richard; Ni, Jian; Chen, Fahu; Kong, Zhaochen; Liu, Guangxui; Liu, Kam-Bui; Liu, Xingqi; Stebich, Martina; Tang, Lingyu; Tian, Fang; Wang, Yongbo; Wischnewski, Juliane; Xu, Qinghai; Yan, Shun; Yang, Zhenjing; Yu, Ge; Zhang, Yun; Zhao, Yan; Zheng, Zhuo (Peer reviewed; Journal article, 2019-05-30)
      Proxy-based reconstructions and modeling of Holocene spatiotemporal precipitation patterns for China and Mongolia have hitherto yielded contradictory results indicating that the basic mechanisms behind the East Asian Summer ...