Blar i Bergen Open Research Archive på tidsskrift "Neuro-Oncology"

Viser treff 1-3 av 3

    • Cancer cell heterogeneity and plasticity: A paradigm shift in glioblastoma 

      Yabo, Yahaya A.; Niclou, Simone Pierrette; Golebiewska, Anna (Journal article; Peer reviewed, 2022)
      Phenotypic plasticity has emerged as a major contributor to intra-tumoral heterogeneity and treatment resistance in cancer. Increasing evidence shows that glioblastoma (GBM) cells display prominent intrinsic plasticity and ...

    • Long-term treatment with valganciclovir improves lentiviral suicide gene therapy of glioblastoma 

      Hossain, Jubayer; Latif, Md Abdul; Ystaas, Lars Andreas Rømo; Ninzima, Sandra; Riecken, Kristoffer; Muller, Arnaud; Azuaje, Fransisco; Vareecal Joseph, Justin; Talasila, Krishna Mukharji; Ghimire, Jiwan; Fehse, Boris; Bjerkvig, Rolf; Miletic, Hrvoje (Peer reviewed; Journal article, 2019)
      Background: Suicide gene therapy for malignant gliomas has shown encouraging results in the latest clinical trials. However, prodrug application was most often restricted to short-term treatment (14 days), especially when ...

    • Surgical resection of glioblastomas induces pleiotrophin-mediated self-renewal of glioblastoma stem cells in recurrent tumors 

      Knudsen, Arnon Møldrup; Halle, Bo; Cédile, Oriane; Burton, Mark; Baun, Christina; Thisgaard, Helge; Anand, Atul; Hubert, Christopher; Thomassen, Mads; Michaelsen, Signe Regner; Olsen, Birgitte Brinkmann; Dahlrot, Rikke Hedegaard; Bjerkvig, Rolf; Lathia, Justin Durla; Kristensen, Bjarne Winther (Journal article; Peer reviewed, 2022)
      Background Glioblastomas are highly resistant to therapy, and virtually all patients experience tumor recurrence after standard-of-care treatment. Surgical tumor resection is a cornerstone in glioblastoma therapy, but its ...