Blar i Bergen Open Research Archive på emneord "Dactolisib"

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    • Dactolisib (NVP-BEZ235) toxicity in murine brain tumour models 

      Netland, I. A; Førde, H. E; Sleire, L.; Leiss, L.; Rahman, M. A; Skeie, B. S; Gjerde, C. H; Enger, P. Ø; Goplen, D. (Peer reviewed; Journal article, 2016-08-19)
      Background: Glioblastomas (GBMs) are highly malignant brain tumours with a poor prognosis, and current cytotoxic regimens provide only a limited survival benefit. The PI3K/Akt/mTOR pathway has been an attractive target for ...