Browsing Bergen Open Research Archive by Subject "zebrafish"
Now showing items 1-4 of 4
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Exploring hnf1ba knockout zebrafish mutant as a model for studying MODY5 disease mechanisms in early pancreas development
(Master thesis, 2023-06-02)Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes, characterised by pancreatic beta-cell dysfunction, early onset (before around 25 years of age), and autosomal dominant inheritance. Heterozygous ... -
Functional assessment of 3'UTR regulatory elements using the zebrafish (Danio rerio) model system - towards modulating protein levels in Atlantic salmon (Salmo salar) for more sustainable aquaculture
(Master thesis, 2021-11-22)Post-transcriptional regulation is a complex process that encompasses a myriad of different structures and mechanisms. There are several indications that regulatory elements in the 3'UTR play an important role in the ... -
The Abundance of PE 18:2 is Increased in Parkinson’s Disease Patient Brain Tissue and DJ-1 Knockout Zebrafish Disease Models
(Master thesis, 2023-06-02)Parkinson’s Disease (PD) is an age-related neurodegenerative disorder associated with both motor and non-motor symptoms. It is characterized by depletion of dopamine-producing neurons in the substantia nigra and the presence ...