Browsing Bergen Open Research Archive by Author "Øyen, Nina"
Now showing items 1-14 of 14
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Association Between Maternal Folic Acid Supplementation and Congenital Heart Defects in Offspring in Birth Cohorts From Denmark and Norway
Øyen, Nina; Olsen, Sjurdur Frodi; Basit, Saima; Leirgul, Elisabeth; Strøm, Marin; Carstensen, Lisbeth; Granström, Charlotta; Tell, Grethe S.; Magnus, Per; Vollset, Stein Emil; Wohlfart, Jan; Melbye, Mads (Peer reviewed; Journal article, 2019-03-19)Background: Evidence linking individual‐level maternal folic acid supplementation to offspring risk of congenital heart defects is lacking. We investigated whether folic acid supplementation in early pregnancy reduces ... -
Birth prevalence of congenital heart defects in Norway 1994-2009—A nationwide study
Leirgul, Elisabeth; Fomina, Tatiana; Brodwall, Kristoffer; Greve, Gottfried; Holmstrøm, Henrik; Vollset, Stein Emil; Tell, Grethe Seppola; Øyen, Nina (Peer reviewed; Journal article, 2014-08-10)Background: The reasons for decreasing birth prevalence of congenital heart defects (CHDs) in several European countries and Canada are not fully understood. We present CHD prevalence among live births, stillbirths, and ... -
General anxiety, depression, and physical health in relation to symptoms of heart-focused anxietya cross sectional study among patients living with the risk of serious arrhythmias and sudden cardiac death
Hamang, Anniken; Eide, Geir Egil; Rokne, Berit; Nordin, Karin; Øyen, Nina (Peer reviewed; Journal article, 2011-11-14)Objective: To investigate the role of three distinct symptoms of heart-focused anxiety (cardio-protective avoidance, heart-focused attention, and fear about heart sensations) in relation to general anxiety, depression and ... -
Health status in patients at risk of inherited arrhythmias and sudden unexpected death compared to the general population
Hamang, Anniken; Eide, Geir Egil; Nordin, Karin; Rokne, Berit; Bjorvatn, Cathrine; Øyen, Nina (Peer reviewed; Journal article, 2010-02-17)Background The possibilities in the molecular genetics of long QT syndrome (LQTS) and hypertrophic cardiomyopathy (HCM) has made family screening, with diagnostic and predictive genetic testing part of the health care offer ... -
Intake of sucrose‑sweetened soft beverages during pregnancy and risk of congenital heart defects (CHD) in ofspring: a Norwegian pregnancy cohort study
Grønning Dale, Maria Teresa; Magnus, Per; Leirgul, Elisabeth; Holmstrøm, Henrik; Gjessing, Håkon K.; Brodwall, Kristoffer; Haugen, Margaretha; Stoltenberg, Camilla; Øyen, Nina (Peer reviewed; Journal article, 2019)Studies report increased risk of congenital heart defects (CHD) in the offspring of mothers with diabetes, where high blood glucose levels might confer the risk. We explored the association between intake of sucrose-sweetened ... -
Maternal Diabetes, Birth Weight, and Neonatal Risk of Congenital Heart Defects in Norway, 1994-2009
Leirgul, Elisabeth; Brodwall, Kristoffer; Greve, Gottfried; Vollset, Stein Emil; Holmstrøm, Henrik; Tell, Grethe S.; Øyen, Nina (Journal article; Peer reviewed, 2016)Objective: To investigate the association between pregestational or gestational diabetes and offspring risk of congenital heart defects and the association between large-for-gestational-age birth weight and risk of cardiac ... -
Maternal use of folic acid and multivitamin supplements and infant risk of birth defects in Norway, 1999–2013
Gildestad, Trude; Bjørge, Tone; Haaland, Øystein Ariansen; Klungsøyr, Kari; Vollset, Stein Emil; Øyen, Nina (Journal article; Peer reviewed, 2020)The association between folic acid supplementation and birth defects other than neural tube defects (NTD) remains unclear. We used a log-binomial regression model to investigate if periconceptional folic acid and/or ... -
Paternal characteristics associated with maternal periconceptional use of folic acid supplementation
Mortensen, Jan Helge Seglem; Øyen, Nina; Nilsen, Roy Miodini; Fomina, Tatiana; Tretli, Steinar; Bjørge, Tone (Peer reviewed; Journal article, 2018-05-30)Background: Maternal predictors of folic acid (FA) supplementation use to reduce offspring risk of neural tube defects are well known, while paternal determinants for maternal FA use are less known. Such knowledge is ... -
Periconceptional Folic Acid Supplementation and Infant Risk of Congenital Heart Defects in Norway 1999-2009
Leirgul, Elisabeth; Gildestad, Trude; Nilsen, Roy Miodini; Fomina, Tatiana; Brodwall, Kristoffer; Greve, Gottfried; Vollset, Stein Emil; Holmstrøm, Henrik; Tell, Grethe Seppola; Øyen, Nina (Peer reviewed; Journal article, 2015)Background The birth prevalence of congenital heart defects (CHDs) has decreased in Canada and Europe. Recommended intake of folic acid in pregnancy is a suggestive risk-reducing factor for CHDs. We investigated the ... -
Preconception cardiovascular risk factor differences between gestational hypertension and preeclampsia: Cohort Norway study
Egeland, Grace M.; Klungsøyr, Kari; Øyen, Nina; Tell, Grethe Seppola; Næss, Øyvind; Skjaerven, Rolv (Peer reviewed; Journal article, 2016)Preconception predictors of gestational hypertension and preeclampsia may identify opportunities for early detection and improve our understanding of the pathogenesis and life course epidemiology of these conditions. Female ... -
Prepregnancy diabetes and offspring risk of congenital heart disease - A nationwide cohort study
Øyen, Nina; Diaz, Lars J; Leirgul, Elisabeth; Boyd, Heather A; Priest, James; Mathiesen, Elisabeth R; Quertermous, Thomas; Wohlfahrt, Jan; Melbye, Mads (Peer reviewed; Journal article, 2016)Background—Maternal diabetes mellitus is associated with an increased risk of offspring congenital heart defects (CHD); however, the causal mechanism is poorly understood. We further investigated this association in a ... -
Risk of Congenital Heart Defects in Offspring of Affected Mothers and Fathers
Øyen, Nina; Boyd, Heather A.; Carstensen, Lisbeth; Søndergaard, Lars; Wohlfahrt, Jan; Melbye, Mads (Journal article; Peer reviewed, 2022)Background: Smaller studies have reported a higher offspring risk of congenital heart defects (CHDs) for mothers with CHDs than for fathers with CHDs. In a large population-based study, we investigated whether offspring ... -
Supplemental folic acid in pregnancy and childhood cancer risk
Mortensen, Jan Helge Seglem; Øyen, Nina; Fomina, Tatiana; Melbye, Mads; Tretli, Steinar; Vollset, Stein Emil; Bjørge, Tone (Peer reviewed; Journal article, 2016)Background: We investigated the association between supplemental folic acid in pregnancy and childhood cancer in a nationwide study of 687 406 live births in Norway, 1999–2010, and 799 children diagnosed later with cancer. ... -
Supplemental folic acid in pregnancy and maternal cancer risk
Mortensen, Jan Helge Seglem; Øyen, Nina; Fomina, Tatiana; Melbye, Mads; Tretli, Steinar; Vollset, Stein Emil; Bjørge, Tone (Peer reviewed; Journal article, 2015-12)Background: There is evidence that increased intake of folate protects against the development of several types of cancer. Some studies have, however, raised concern about the safety of folate in relation to cancer risk. ...