Browsing Bergen Open Research Archive by Author "Aasland, Rein"

Now showing items 1-4 of 4

    • The Arabidopsis (ASHH2) CW domain binds monomethylated K4 of the histone H3 tail through conformational selection 

      Dobrovolska, Olena; Brilkov, Maxim; Madeleine, Noëlly; Ødegaard-Fougner, Øyvind; Strømland, Øyvind; Martin, Stephen R.; De Marco, Valeria; Christodoulou, Evangelos; Teigen, Knut; Isaksson, Johan; Underhaug, Jarl; Reuter, Nathalie; Aalen, Reidunn B.; Aasland, Rein; Halskau, Øyvind (Journal article; Peer reviewed, 2020)
      Chromatin post‐translational modifications are thought to be important for epigenetic effects on gene expression. Methylation of histone N‐terminal tail lysine residues constitutes one of many such modifications, executed ...

    • Binding Specificity of ASHH2 CW Domain Toward H3K4me1 Ligand Is Coupled to Its Structural Stability Through Its α1-Helix 

      Bril'kov, Maxim; Dobrovolska, Olena; Ødegård-Fougner, Øyvind; Turcu, Diana Cornelia; Strømland, Øyvind; Underhaug, Jarl; Aasland, Rein; Halskau, Øyvind (Journal article; Peer reviewed, 2022-04-13)
      The CW domain binds to histone tail modifications found in different protein families involved in epigenetic regulation and chromatin remodeling. CW domains recognize the methylation state of the fourth lysine on histone ...

    • ELM: the status of the 2010 eukaryotic linear motif resource 

      Gould, Cathryn M.; Diella, Francesca; Via, Allegra; Puntervoll, Pål; Gemünd, Christine; Chabanis-Davidson, Sophie; Michael, Sushama; Sayadi, Ahmed; Bryne, Jan Christian; Chica, Claudia; Seiler, Markus; Davey, Norman E.; Haslam, Neill; Weatheritt, Robert J.; Budd, Aidan; Hughes, Timothy; Pas, Jakub; Rychlewski, Leszek; Trave, Gilles Michel; Aasland, Rein; Helmer-Citterich, Manuela; Linding, Rune; Gibson, Toby J. (Peer reviewed; Journal article, 2009-11-17)
      Linear motifs are short segments of multidomain proteins that provide regulatory functions independently of protein tertiary structure. Much of intracellular signalling passes through protein modifications at linear motifs. ...

    • The Schizosaccharomyces pombe JmjC-protein, Msc1, prevents H2A.Z localization in centromeric and subtelomeric chromatin domains 

      Buchanan, Luke; Durand-Dubief, Mickaël; Roguev, Assen; Cagri, Sakalar; Wilhelm, Brian; Stålfors, Annelie; Shevchenko, Anna; Aasland, Rein; Shevchenko, Andrej; Ekwall, Karl; Stewart, Francis (Peer reviewed; Journal article, 2009-11-13)
      Eukaryotic genomes are repetitively packaged into chromatin by nucleosomes, however they are regulated by the differences between nucleosomes, which establish various chromatin states. Local chromatin cues direct the ...