• Associations of preconception exposure to air pollution and greenness with offspring asthma and hay fever 

      Kuiper, Ingrid Nordeide; Markevych, Iana; Accordini, Simone; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Christensen, Jesper Heile; Forsberg, Bertil; Halvorsen, Thomas; Heinrich, Joachim; Hertel, Ole; Hoek, Gerard; Holm, Mathias; de Hoogh, Kees; Janson, Christer; Malinovschi, Anderi; Marcon, Alessandro; Sigsgaard, Torben; Svanes, Cecilie; Johannessen, Ane (Journal article; Peer reviewed, 2020)
      We investigated if greenness and air pollution exposure in parents’ childhood affect offspring asthma and hay fever, and if effects were mediated through parental asthma, pregnancy greenness/pollution exposure, and offspring ...
    • Atopy Modifies the Association Between Inhaled Corticosteroid Use and Lung Function Decline in Patients with Asthma 

      Marcon, Alessandro; Marchetti, P; Anto, J.M.; Cazzoletti, Lucia; Cerveri, Isa; Corsico, Angelo; Ferreira, D.S.; Garcia-Aymerich, Judith; Gislason, David; Heinrich, Joachim; Jögi, Rain; Johannessen, Ane; Leynaert, Benedicte; Malinovschi, Andrei; Pin, Isabelle; Probst-Hensch, Nicole; Weyler, Joost; Janson, Christer; Jarvis, Deborah; Accordini, Simone (Peer reviewed; Journal article, 2020)
      Background: Inhaled corticosteroids (ICSs) are the mainstay of asthma treatment, but response to medication is variable. Patients with allergic inflammation generally show a better short-term response to ICSs; however, ...
    • Being overweight in childhood, puberty, or early adulthood: Changing asthma risk in the next generation? 

      Johannessen, Ane; Lønnebotn, Marianne; Calciano, Lucia; Benediktsdóttir, Bryndís; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Dharmage, Shyamali; Franklin, Karl A.; Gíslason, Þórarinn; Holm, Mathias; Janson, Christer; Jarvis, Deborah; Jõgi, Rain; Kim, Jeong-Lim; Kirkeleit, Jorunn; Lodge, Caroline; Malinovschi, Andrei; Martinez-Moratalla, Jesus; Nilsen, Roy Miodini; Pereira-Vega, Antonio; Gomez Real, Francisco; Schlünssen, Vivi; Accordini, Simone; Svanes, Cecilie (Peer reviewed; Journal article, 2020-03)
      Background Overweight status and asthma have increased during the last decades. Being overweight is a known risk factor for asthma, but it is not known whether it might also increase asthma risk in the next generation. ...
    • Body silhouettes as a tool to reflect obesity in the past 

      Lønnebotn, Marianne; Svanes, Cecilie; Igland, Jannicke; Franklin, Karl A.; Accordini, Simone; Benediktsdóttir, Bryndís; Bentohuami, Hayat; Blanco, José Antonio Gullón; Bono, Roberto; Corsico, Angelo; Demoly, Pascal; Dharmage, Shyamali; Dorado Arenas, Sandra; Garcia, Judith; Heinrich, Joachim; Holm, Mathias; Janson, Christer; Jarvis, Deborah; Leynaert, Bénédicte; Martinez-Moratalla, Jesús; Nowak, Dennis; Pin, Isabelle; Raherison-Semjen, Chantal; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Skulstad, Svein Magne; Dratva, Julia; Gomez Real, Francisco (Peer reviewed; Journal article, 2018-04-25)
      Life course data on obesity may enrich the quality of epidemiologic studies analysing health consequences of obesity. However, achieving such data may require substantial resources. We investigated the use of body silhouettes ...
    • Determinants of fractional exhaled nitric oxide in healthy men and women from the European Community Respiratory Health Survey III 

      Nerpin, Elisabet; Olivieri, Mario; Gislason, Thorainn; Olin, Anna C.; Nielsen, Rune; Johannessen, Ane; Ferreira, Diogenes S.; Marcon, Alessandro; Cazzoletti, Lucia; Accordini, Simone; Pin, Isabelle; Corsico, Angelo; Demoly, Pascal; Weyler, Joost; Nowak, Dennis; Jõgi, Rain; Forsberg, Bertil; Zock, Jan P.; Sigsgaard, Torben; Heinric, Joachim; Bono, Roberto; Leynaert, Bénédicte; Jarvis, Deborah; Janson, Christer; Malinovschi, Anderi (Peer reviewed; Journal article, 2019)
      Introduction: The fractional exhaled nitric oxide (FENO ) is a marker for type 2 inflammation used in diagnostics and management of asthma. In order to use FENO as a reliable biomarker, it is important to investigate factors ...
    • Exogenous female sex steroids may reduce lung ageing after menopause: A 20-year follow-up study of a general population sample (ECRHS) 

      Triebner, Kai; Accordini, Simone; Calciano, Lucia; Johannessen, Ane; Benediktsdóttir, Bryndís; Bifulco, Ersilia; Demoly, Pascal; Dharmage, Shyamali C.; Franklin, Karl A.; Garcia-Aymerich, Judith; Gullón Blanco, José Antonio; Heinrich, Joachim; Holm, Mathias; Jarvis, Debbie; Jõgi, Rain; Lindberg, Eva; Martínez-Moratalla, Jesús; Muniozguren Agirre, Nerea; Pin, Isabelle; Probst-Hensch, Nicole; Raherison, Chantal; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Svanes, Cecilie; Hustad, Simon Steinar; Leynaert, Bénédicte; Gomez Real, Francisco (Peer reviewed; Journal article, 2019)
      Objectives: Menopause involves hypoestrogenism, which is associated with numerous detrimental effects, including on respiratory health. Hormone replacement therapy (HRT) is often used to improve symptoms of menopause. The ...
    • Interaction between gas cooking and GSTM1 null genotype in bronchial responsiveness: Results from the European Community Respiratory Health Survey 

      Amaral, André F.S.; Ramasamy, Adaikalavan; Castro-Giner, Francesc; Minelli, Cosetta; Accordini, Simone; Sørheim, Inga Cecilie; Pin, Isabelle; Kogevinas, Manolis; Jõgi, Rain; Balding, David J.; Norbäck, Dan; Verlato, Guiseppe; Olivieri, Mario; Probst-Hensch, Nicole; Janson, Christer; Zock, Jan-Paul; Heinrich, Joachim; Jarvis, Deborah L. (Peer reviewed; Journal article, 2014)
      Background: Increased bronchial responsiveness is characteristic of asthma. Gas cooking, which is a major indoor source of the highly oxidant nitrogen dioxide, has been associated with respiratory symptoms and reduced lung ...
    • Pharmacological treatment of asthma in a cohort of adults during a 20-year period: results from the European Community Respiratory Health Survey I, II and III 

      Janson, Christer; Accordini, Simone; Cazzoletti, Lucia; Cerveri, Isa; Chanoine, S; Corsico, Angelo; Ferreira, D.S.; Garcia-Aymerich, Judith; Gislason, Thorarinn; Nielsen, Rune; Johannessen, Ane; Jõgi, Rain; Malinovschi, Andrei; Moratalla, Jesús Martínez; Marcon, Alessandro; Pin, Isabelle; Quint, JK; Siroux, Valerie; Almar, Enrique; Bellisario, Valeria; Franklin, Karl A.; Gullon, JA; Holm, Mathias; Heinrich, Joachim; Nowak, Dennis; Sánchez-Ramos, José Luis; Weyler, Joost; Jarvis, Deborah (Peer reviewed; Journal article, 2019)
      Asthma often remains uncontrolled, despite the fact that the pharmacological treatment has undergone large changes. We studied changes in the treatment of asthma over a 20-year period and identified factors associated with ...
    • Restrictive spirometry pattern is associated with low physical activity levels. A population based international study 

      Carsin, Anne-Elie; Fuertes, Elaine; Schaffner, Emmanuel; Jarvis, Debbie; Antó, Josep M.; Heinrich, Joachim; Bellisario, Valeria; Svanes, Cecilie; Keidel, Dirk; Imboden, Medea; Weyler, Joost; Nowak, Dennis; Martínez-Moratalla, Jesús; Gullón, José-Antonio; Sánchez Ramos, José Luis; Caviezel, Seraina; Beckmeyer-Borowko, Anna; Raherison, Chantal; Pin, Isabelle; Demoly, Pascal; Cerveri, Isa; Accordini, Simone; Gislason, Þórarinn; Torén, Kjell; Forsberg, Bertil; Janson, Christer; Jõgi, Rain; Emtner, Margareta; Gomez Real, Francisco; Raza, Wasif; Leynaert, Bénédicte; Pascual, Silvia; Guerra, Stefano; Dharmage, Shyamali C.; Probst-Hensch, Nicole; Garcia-Aymerich, Judith (Peer reviewed; Journal article, 2019)
      Introduction: Restrictive spirometry pattern is an under-recognised disorder with a poor morbidity and mortality prognosis. We compared physical activity levels between adults with a restrictive spirometry pattern and with ...
    • Trends in smoking initiation in Europe over 40 years: A retrospective cohort study 

      Marcon, Alessandro; Pesce, Giancarlo; Calciano, Lucia; Bellisario, Valeria; Dharmage, Shyamali C.; Garcia-Aymerich, Judith; Gislasson, Thorarinn; Heinrich, Joachim; Holm, Mathias; Janson, Christer; Jarvis, Deborah; Leynaert, Bénédicte; Matheson, Melanie C.; Pirina, Pietro; Svanes, Cecilie; Villani, Simona; Zuberbier, Torsten; Minelli, Cosetta; Accordini, Simone (Journal article; Peer reviewed, 2018)
      Background Tobacco consumption is the largest avoidable health risk. Understanding changes of smoking over time and across populations is crucial to implementing health policies. We evaluated trends in smoking initiation ...