Browsing Bergen Open Research Archive by Author "Al-Sharabi, Niyaz Abdulbaqi Abdulmajid"
Now showing items 1-9 of 9
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Brief communication: Effects of conditioned media from human platelet lysate cultured MSC on osteogenic cell differentiation in vitro
Shanbhag, Siddharth; Al-Sharabi, Niyaz Abdulbaqi Abdulmajid; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Gruber, Reinhard; Kristoffersen, Einar Klæboe; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2022)Culturing mesenchymal stromal cells (MSC) in human platelet lysate (HPL) supplemented media can enhance their osteogenic differentiation potential. The objective of this study was to test the hypothesis that conditioned ... -
Conditioned Medium from Bone Marrow Mesenchymal Stem Cells Restored Oxidative Stress-Related Impaired Osteogenic Differentiation
Saleem, Ragda; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Elnour, Rammah; Berggreen, Ellen; Mustafa, Kamal Babikeir Elnour; Al-Sharabi, Niyaz Abdulbaqi Abdulmajid (Journal article; Peer reviewed, 2021)Oxidative stress from high levels of intracellular reactive oxygen species (ROS) has been linked to various bone diseases. Previous studies indicate that mesenchymal stem cells (MSC) secrete bioactive factors (conditioned ... -
Extracellular Vesicles Derived from Primed Mesenchymal Stromal Cells Loaded on Biphasic Calcium Phosphate Biomaterial Exhibit Enhanced Macrophage Polarization
Rana, Neha; Suliman, Salwa; Al-Sharabi, Niyaz Abdulbaqi Abdulmajid; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2022)Mesenchymal stromal cells (MSC) loaded on biphasic calcium phosphate biomaterial (MSC + BCP) have been used as an advanced therapy medicinal product to treat complex maxillofacial bone defects in patients. Further, MSC-derived ... -
Functionalizing Collagen Membranes with MSC-Conditioned Media Promotes Guided Bone Regeneration in Rat Calvarial Defects
Shanbhag, Siddharth; Kampleitner, Carina; Al-Sharabi, Niyaz Abdulbaqi Abdulmajid; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Apaza Alccayhuaman, Karol Ali; Heimel, Patrick; Tangl, Stefan; Beinlich, Andreas Michael; Rana, Neha; Sanz, Mariano; Kristoffersen, Einar Klæboe; Mustafa, Kamal Babikeir Elnour; Gruber, Reinhard (Journal article; Peer reviewed, 2023-02-28)Functionalizing biomaterials with conditioned media (CM) from mesenchymal stromal cells (MSC) is a promising strategy for enhancing the outcomes of guided bone regeneration (GBR). This study aimed to evaluate the bone ... -
The Gingiva from the Tissue Surrounding the Bone to the Tissue Regenerating the Bone: A Systematic Review of the Osteogenic Capacity of Gingival Mesenchymal Stem Cells in Preclinical Studies
Al-Qadhi, Gamilah; Aboushady, Iman; Al-Sharabi, Niyaz Abdulbaqi Abdulmajid (Journal article; Peer reviewed, 2021)The current review aims to systematically assess the osteogenic capacity of gingiva-derived mesenchymal stem cells (GMSCs) in preclinical studies. A comprehensive electronic search of PubMed, Embase, Web of Science, and ... -
Harnessing the Antioxidative Potential of Dental Pulp Stem Cell-Conditioned Medium in Photopolymerized GelMA Hydrogels
Yamada, Shuntaro; Al-Sharabi, Niyaz Abdulbaqi Abdulmajid; Torelli, Francesco; Angelova Volponi, Ana; Sandven, Linda; Ueda, Minoru; Fristad, Inge; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2024)Gelatin methacryloyl (GelMA) stands out for its biocompatibility, tunability, and functionality, being often selected as a scaffolding material. However, the biological modulations induced by its photocrosslinking process ... -
The neuroprotective potential of mesenchymal stem cells from bone marrow and human exfoliated deciduous teeth in a murine model of demyelination
Kråkenes, Torbjørn; Wergeland, Stig; Al-Sharabi, Niyaz Abdulbaqi Abdulmajid; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Fromreide, Siren; Costea, Daniela Elena; Mustafa, Kamal Babikeir Elnour; Bø, Lars; Kvistad, Christopher Elnan (Journal article; Peer reviewed, 2023)Introduction Multiple sclerosis (MS) is characterized by chronic inflammation, demyelination, and axonal degeneration within the central nervous system (CNS), for which there is no current treatment available with the ... -
Proteomic Analysis of Mesenchymal Stromal Cells Secretome in Comparison to Leukocyte- and Platelet-Rich Fibrin
Al-Sharabi, Niyaz Abdulbaqi Abdulmajid; Gruber, Reinhard; Sanz, Mariano; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Kristoffersen, Einar Klæboe; Mustafa, Kamal Babikeir Elnour; Shanbhag, Siddharth (Journal article; Peer reviewed, 2023)Secretomes of mesenchymal stromal cells (MSCs) are emerging as a novel growth factor (GF)-based strategy for periodontal and bone regeneration. The objective of this study was to compare the secretome of human bone marrow ... -
The use of mesenchymal stromal cell secretome to enhance guided bone regeneration in comparison with leukocyte and platelet-rich fibrin
Shanbhag, Siddharth; Al-Sharabi, Niyaz Abdulbaqi Abdulmajid; Kampleitner, Carina; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Kristoffersen, Einar Klæboe; Tangl, Stefan; Mustafa, Kamal Babikeir Elnour; Gruber, Reinhard; Sanz, Mariano (Journal article; Peer reviewed, 2024)Objectives Secretomes of mesenchymal stromal cells (MSC) represent a novel strategy for growth-factor delivery for tissue regeneration. The objective of this study was to compare the efficacy of adjunctive use of ...