Browsing Bergen Open Research Archive by Author "Altankhuyag, Altanchimeg"
Now showing items 1-3 of 3
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A polybasic motif in ErbB3-binding protein 1 (EBP1) has key functions in nucleolar localization and polyphosphoinositide interaction
Karlsson, Thomas; Altankhuyag, Altanchimeg; Dobrovolska, Olena; Turcu, Diana Cornelia; Lewis, Aurelia Eva (Peer reviewed; Journal article, 2016-07)Polyphosphoinositides (PPIns) are present in the nucleus where they participate in crucial nuclear processes, such as chromatin remodelling, transcription and mRNA processing. In a previous interactomics study, aimed to ... -
Polyphosphoinositides in the nucleus: Roadmap of their effectors and mechanisms of interaction
Jacobsen, Rhian Gaenor; Gavgani, Fatemeh Mazloumi; Edson, Amanda Jayne; Goris, Marianne; Altankhuyag, Altanchimeg; Lewis, Aurelia Eva (Peer reviewed; Journal article, 2019)Biomolecular interactions between proteins and polyphosphoinositides (PPIn) are essential in the regulation of the vast majority of cellular processes. Consequently, alteration of these interactions is implicated in the ... -
Tetrahydrobiopterin (BH<inf>4</inf>) treatment stabilizes tyrosine hydroxylase: Rescue of tyrosine hydroxylase deficiency phenotypes in human neurons and in a knock-in mouse model
K C, Kunwar Jung; Tristán-Noguero, Alba; Altankhuyag, Altanchimeg; Piñol Belenguer, David; Prestegård, Karina Skjervheim; Fernandez-Carasa, Irene; Colini Baldeshi, Arianna; Sigatulina Bondarenko, Maria; García-Cazorla, Angeles; Consiglio, Antonella; Martinez, Aurora (Journal article; Peer reviewed, 2024)Proteostatic regulation of tyrosine hydroxylase (TH), the rate-limiting enzyme in dopamine biosynthesis, is crucial for maintaining proper brain neurotransmitter homeostasis. Variants of the TH gene are associated with ...