Browsing Bergen Open Research Archive by Author "Alvestad, Silje"

Now showing items 1-11 of 11

    • Association of Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability 

      Bjørk, Marte-Helene; Zoega, Helga; Leinonen, Maarit K.; Cohen, Jacqueline Mallory; Dreier, Julie Werenberg; Furu, Kari; Gilhus, Nils Erik; Gissler, Mika; Halfdanarson, Oskar; Igland, Jannicke; Sun, Yuelian; Tomson, Torbjörn; Alvestad, Silje; Christensen, Jakob (Journal article; Peer reviewed, 2022)
      Importance: Women with epilepsy frequently need antiseizure medication (ASM) to prevent seizures in pregnancy. Risk of neurodevelopmental disorders after prenatal exposure to AMSs is uncertain. Objective: To determine ...

    • Cancer risk in children of mothers with epilepsy and high-dose folic acid use during pregnancy 

      Vegrim, Håkon Magne; Dreier, Julie Werenberg; Alvestad, Silje; Gilhus, Nils Erik; Gissler, Mika; Igland, Jannicke; Leinonen, Maarit; Tomson, Torbjörn; Sun, Yuelian; Zoega, Helga; Christensen, Jakob; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)
      Importance: Women with epilepsy are recommended high doses of folic acid before and during pregnancy owing to risk of congenital anomalies associated with antiseizure medications. Whether prenatal exposure to high-dose ...

    • Cardiac Structure and Function in Epilepsy Patients with Drug-Resistant Convulsive Seizures 

      Gonzalez, Alba; Haugaa, Kristina Ingrid Helena Hermann; Brekke, Pål Haugar; Hopp, Einar; Ørn, Stein; Alvestad, Silje; Taubøll, Erik; Aurlien, Dag (Journal article; Peer reviewed, 2022)
      High frequency of convulsive seizures and long-lasting epilepsy are associated with an increased risk of sudden unexpected death in epilepsy (SUDEP). Structural changes in the myocardium have been described in SUDEP victims. ...

    • Cardiac Structure and Function in Epilepsy Patients with Drug-Resistant Convulsive Seizures 

      Gonzalez, Alba; Haugaa, Kristina Ingrid Helena Hermann; Brekke, Pål Haugar; Hopp, Einar; Ørn, Stein; Alvestad, Silje; Taubøll, Erik; Aurlien, Dag (Journal article; Peer reviewed, 2022)
      High frequency of convulsive seizures and long-lasting epilepsy are associated with an increased risk of sudden unexpected death in epilepsy (SUDEP). Structural changes in the myocardium have been described in SUDEP victims. ...

    • Comparative Risk of Major Congenital Malformations With Antiseizure Medication Combinations vs Valproate Monotherapy in Pregnancy 

      Cohen, Jacqueline Mallory; Alvestad, Silje; Suarez, Elizabeth A.; Schaffer, Andrea; Selmer, Randi M.; Havard, Alys; Bateman, Brian T.; Cesta, Carolyn E.; Zoega, Helga; Odsbu, Ingvild; Huybrechts, Krista F.; Kjerpeseth, Lars J.; Straub, Loreen; Leinonen, Maarit K.; Bjørk, Marte-Helene; Nørgaard, Mette; Gissler, Mika; Ulrichsen, Sinna P.; Hernandez-Diaz, Sonia; Tomson, Torbjörn; Furu, Kari (Journal article; Peer reviewed, 2023)
      Background and Objectives Valproate should be avoided in pregnancy, but it is the most effective drug for generalized epilepsies. Alternative treatment may require combinations of other drugs. Our objectives were to ...

    • Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations 

      Cohen, Jacqueline Mallory; Alvestad, Silje; Cesta, Carolyn E.; Bjørk, Marte-Helene; Leinonen, Maarit; Nørgaard, Mette; Einarsdóttir, Kristjana; Engeland, Anders; Gissler, Mika; Karlstad, Øystein; Klungsøyr, Kari; Odsbu, Ingvild; Reutfors, Johan; Selmer, Randi Marie; Tomson, Torbjörn; Ulrichsen, Sinna Pilgaard; Zoega, Helga; Furu, Kari (Journal article; Peer reviewed, 2022)
      Objective: This study was undertaken to examine the comparative safety of antiseizure medication (ASM) monotherapy in pregnancy with respect to risk of major congenital malformations (MCMs), overall and by MCM subtype. ...

    • Folic Acid and Risk of Preterm Birth, Preeclampsia, and Fetal Growth Restriction Among Women With Epilepsy A Prospective Cohort Study 

      Alvestad, Silje; Husebye, Elisabeth Synnøve Nilsen; Christensen, Jakob; Dreier, Julie Werenberg; Sun, Yuelian; Igland, Jannicke; Leinonen, Maarit; Gissler, Mika; Gilhus, Nils Erik; Tomson, Torbjörn; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)
      Background and Objectives Women with epilepsy treated with antiseizure medication (ASM) have increased risk of pregnancy complications including preterm birth, fetal growth restriction, and preeclampsia. We aimed to ...

    • Identification of novel genomic risk loci shared between common epilepsies and psychiatric disorders 

      Karadag, Naz; Shadrin, Alexey; O'Connell, Kevin S; Hindley, Guy Frederick Lanyon; Rahman, Zillur; Parker, Nadine; Bahrami, Shahram; Fominykh, Vera; Cheng, Weiqiu; Holen, Børge; Alvestad, Silje; Taubøll, Erik; Steen, Nils Eiel; Djurovic, Srdjan; Dale, Anders M; Frei, Oleksandr; Andreassen, Ole; Smeland, Olav Bjerkehagen (Journal article; Peer reviewed, 2023)
      Psychiatric disorders and common epilepsies are heritable disorders with a high comorbidity and overlapping symptoms. However, the causative mechanisms underlying this relationship are poorly understood. Here we aimed to ...

    • Pregnancy, folic acid, and antiseizure medication 

      Bjørk, Marte-Helene; Vegrim, Håkon Magne; Alvestad, Silje; Monsen, Anne-Lise Bjørke; Riedel, Bettina Maria Ingeborg; Gilhus, Nils Erik; Husebye, Elisabeth Synnøve Nilsen (Journal article; Peer reviewed, 2023)
      Background Although some antiseizure medications (ASMs) are teratogenic, most people with epilepsy need treatment in pregnancy. The risk of ASM fetotoxicity may be mitigated with folic acid. High-dose folic acid ...

    • Prescribing patterns for higher dose folic acid in pregnant women with epilepsy treated with antiseizure medication 

      Vegrim, Håkon Magne; Dreier, Julie Werenberg; Igland, Jannicke; Gilhus, Nils Erik; Alvestad, Silje; Gissler, Mika; Leinonen, Maarit; Sun, Yuelian; Zoega, Helga; Christensen, Jakob; Bjørk, Marte-Helene; Tomson, Torbjörn (Journal article; Peer reviewed, 2024)
      Objective: This study was undertaken to characterize the use of higher doses of folic acid (≥1 mg daily) in relation to pregnancy in Denmark, Norway, and Sweden in women with epilepsy treated with antiseizure medication ...

    • Socioeconomic differences in use of antiseizure medication in pregnancies with maternal epilepsy: A population-based study from Nordic universal health care systems 

      Leinonen, Maarit K.; Igland, Jannicke; Dreier, Julie Werenberg; Alvestad, Silje; Cohen, Jacqueline Mallory; Gilhus, Nils Erik; Gissler, Mika; Sun, Yuelian; Tomson, Torbjörn; Zoega, Helga; Vegrim, Håkon Magne; Christensen, Jakob; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2024)
      Objective Research points to disparities in disease burden and access to medical care in epilepsy. We studied the association between socioeconomic status (SES) and antiseizure medication (ASM) use in pregnancies with ...