• Cross-sectional study on exhaled nitric oxide in relation to upper airway inflammatory disorders with regard to asthma and perennial sensitization 

      Krantz, Christina; Accordini, Simone; Alving, Kjell; Corsico, Angelo G.; Demoly, Pascal; Ferreira, Diogenes S.; Forsberg, Bertil; Garcia-Aymerich, Judith; Gislason, Thorarinn; Heinrich, Joachim; Jõgi, Rain; Johannessen, Ane; Leynaert, Bénédicte; Marcon, Alessandro; Martínez-Moratalla Rovira, Jesús; Nerpin, Elisabet; Nowak, Dennis; Olin, Anna-Carin; Olivieri, Mario; Pereira-Vega, Antonio; Raherison-Semjen, Chantal; Real, Francisco Gomez; Sigsgaard, Torben; Squillacioti, Giulia; Janson, Christer; Malinovschi, Andrei (Journal article; Peer reviewed, 2022)
      Background: Fractional exhaled nitric oxide (FeNO) is a well-known marker of type-2 inflammation. FeNO is elevated in asthma and allergic rhinitis, with IgE sensitization as a major determinant. Objective: We aimed to ...
    • Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation: A Clinical Observational Study 

      Kolmert, Johan; Gómez, Cristina; Balgoma, David; Sjödin, Marcus; Bood, Johan; Konradsen, Jon R.; Ericsson, Magnus; Thörngren, John-Olof; James, Anna; Mikus, Maria; Sousa, Ana R.; Riley, John H.; Bates, Stewart; Bakke, Per S.; Pandis, Ioannis; Caruso, Massimo; Chanez, Pascal; Fowler, Stephen J.; Geiser, Thomas; Howarth, Peter; Horváth, Ildikó; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Behndig, Annelie; Shaw, Dominick E.; Knowles, Richard G.; Holweg, Cécile T.J.; Wheelock, Åsa M.; Dahlen, Barbro; Nordlund, Björn; Alving, Kjell; Hedlin, Gunilla; Chung, Kian Fan; Adcock, Ian M.; Sterk, Peter J.; Djukanovic, Ratko; Dahlén, Sven-Erik; Wheelock, Craig E. (Journal article; Peer reviewed, 2021)
      Rationale: New approaches are needed to guide personalized treatment of asthma. Objectives: To test if urinary eicosanoid metabolites can direct asthma phenotyping. Methods: Urinary metabolites of prostaglandins ...