Blar i Bergen Open Research Archive på forfatter "Apalset, Ellen M."
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Interferon (IFN)-γ-mediated inflammation and the kynurenine pathway in relation to bone mineral density: the Hordaland Health Study
Apalset, Ellen M.; Gjesdal, Clara Gram; Ueland, Per Magne; Midttun, Øyvind; Ulvik, Arve; Eide, Geir Egil; Meyer, Klaus; Tell, Grethe Seppola (Peer reviewed; Journal article, 2014-04-24)The risk of osteoporosis increases in inflammatory disorders. In cell-mediated immune activation, interferon (IFN)-γ stimulates macrophage release of neopterin and increases the activity of indoleamine 2,3-dioxygenase ... -
Interferon gamma (IFN-γ)-mediated inflammation and the kynurenine pathway in relation to risk of hip fractures: The Hordaland Health Study
Apalset, Ellen M.; Gjesdal, Clara Gram; Ueland, Per Magne; Øyen, Jannike; Meyer, Klaus; Midttun, Øivind; Eide, Geir Egil; Tell, Grethe Seppola (Peer reviewed; Journal article, 2014-05-10)Summary The cytokine interferon gamma (IFN-γ) stimulates neopterin release and tryptophan degradation into kynurenines through the kynurenine pathway. High levels of neopterin were associated with increased hip fracture ... -
Smoking and body fat mass in relation to bone mineral density and hip fracture: The Hordaland Health Study
Øyen, Jannike; Gjesdal, Clara Gram; Nygård, Ottar; Lie, Stein Atle; Meyer, Haakon; Apalset, Ellen M.; Ueland, Per Magne; Pedersen, Eva Kristine Ringdal; Midttun, Øivind; Vollset, Stein Emil; Tell, Grethe Seppola (Peer reviewed; Journal article, 2014-03-25)Lower bone mineral density (BMD) in smokers may be attributable to lower body weight or fat mass, rather than to a direct effect of smoking. We analyzed the effects of smoking exposure, assessed by plasma cotinine, and ...