Browsing Bergen Open Research Archive by Author "Aukrust, Ingvild"

Now showing items 1-20 of 24

    • Association of a Low-Frequency Variant in HNF1A With Type 2 Diabetes in a Latino Population 

      Estrada, Karol; Aukrust, Ingvild; Bjørkhaug, Lise; Najmi, Laeya Abdoli; Njølstad, Pål Rasmus; MacArthur, Daniel G.; The SIGMA Type 2 Diabetes Consortium (Peer reviewed; Journal article, 2014-06)
      Importance: Latino populations have one of the highest prevalences of type 2 diabetes worldwide. Objectives: To investigate the association between rare protein-coding genetic variants and prevalence of type 2 diabetes in ...

    • BRCA1 Norway: comparison of classifcation for BRCA1 germline variants detected in families with suspected hereditary breast and ovarian cancer between different laboratories 

      Hovland, Henrikke Nilsen; Al-Adhami, Rafal; Ariansen, Sarah Louise; Van Ghelue, Marijke; Sjursen, Wenche; Anfinsen, Sigrid Lima; Bolstad, Marte; Berger, Amund Holte; Vetti, Hildegunn Høberg; Knappskog, Per Morten; Haukanes, Bjørn Ivar; Aukrust, Ingvild; Ognedal, Elisabet (Journal article; Peer reviewed, 2022)
      Pathogenic germline variants in Breast cancer susceptibility gene 1 (BRCA1) predispose carriers to hereditary breast and ovarian cancer (HBOC). Through genetic testing of patients with suspected HBOC an increasing number ...

    • Characterisation of HNF1A variants in paediatric diabetes in Norway using functional and clinical investigations to unmask phenotype and monogenic diabetes 

      Svalastoga, Pernille; Kaci, Alba; Molnes, Janne; Solheim, Marie Holm; Johansson, Bente Berg; Krogvold, Lars; Skrivarhaug, Torild; Valen, Eivind; Johansson, Stefan; Molven, Anders; Sagen, Jørn Vegard; Søfteland, Eirik; Bjørkhaug, Lise; Tjora, Erling; Aukrust, Ingvild; Njølstad, Pål Rasmus (Journal article; Peer reviewed, 2023)
      Aims/hypothesis Correctly diagnosing MODY is important, as individuals with this diagnosis can discontinue insulin injections; however, many people are misdiagnosed. We aimed to develop a robust approach for determining ...

    • Chip protein U-box domain truncation affects Purkinje neuron morphology and leads to behavioral changes in zebrafish 

      Pakdaman, Yasaman; Denker, Elsa; Austad, Eirik; Norton, William H.J.; Rolfsnes, Hans Olav; Bindoff, Laurence Albert; Tzoulis, Charalampos; Aukrust, Ingvild; Knappskog, Per Morten; Johansson, Stefan; Ellingsen, Ståle (Journal article; Peer reviewed, 2021-09-24)
      The ubiquitin ligase CHIP (C-terminus of Hsc70-interacting protein) is encoded by STUB1 and promotes ubiquitination of misfolded and damaged proteins. CHIP deficiency has been linked to several diseases, and mutations in ...

    • Clinical Cases and the Molecular Profiling of a Novel Childhood Encephalopathy-Causing GNAO1 Mutation P170R 

      Larasati, Yonika A.; Solis, Gonzalo P.; Koval, Alexey; Griffiths, Silja Torvik; Berentsen, Ragnhild Drage; Aukrust, Ingvild; Lesca, Gaetan; Chatron, Nicolas; Ville, Dorothée; Korff, Christian M.; Katanaev, Vladimir L. (Journal article; Peer reviewed, 2023)
      De novo mutations in GNAO1, the gene encoding the major neuronal G protein Gαo, cause a spectrum of pediatric encephalopathies with seizures, motor dysfunction, and developmental delay. Of the >80 distinct missense pathogenic ...

    • The contribution of functional HNF1A variants and polygenic susceptibility to risk of type 2 diabetes in ancestrally diverse populations 

      Stalbow, Lauren; Preuss, Michael H.; Smit, Roelof A.J.; Chami, Nathalie; Bjørkhaug, Lise; Aukrust, Ingvild; Gloyn, Anna L; Loos, Ruth J.F. (Journal article; Peer reviewed, 2023)
      Aims/hypothesis: We examined the contribution of rare HNF1A variants to type 2 diabetes risk and age of diagnosis, and the extent to which their impact is affected by overall genetic susceptibility, across three ancestry ...

    • Dominant ARL3-related retinitis pigmentosa 

      Holtan, Josephine Prener; Teigen, Knut; Aukrust, Ingvild; Bragadottir, Ragnheidur; Houge, Gunnar (Peer reviewed; Journal article, 2019)
      Purpose: To clinically and genetically characterise a second family with dominant ARL3-related retinitis pigmentosa due to a specific ARL3 missense variant, p.(Tyr90Cys). Methods: Clinical examination included optical ...

    • The E3 SUMO ligase PIASγ is a novel interaction partner regulating the activity of diabetes associated hepatocyte nuclear factor-1α 

      Kaci, Alba; Keindl, Magdalena; Solheim, Marie Holm; Njølstad, Pål Rasmus; Bjørkhaug, Lise; Aukrust, Ingvild (Peer reviewed; Journal article, 2018-08-24)
      The transcription factor hepatocyte nuclear factor-1α (HNF-1A) is involved in normal pancreas development and function. Rare variants in the HNF1A gene can cause monogenic diabetes, while common variants confer type 2 ...

    • Effective interventions in preventing gestational diabetes mellitus: A systematic review and meta-analysis 

      Takele, Wubet Worku; Vesco, Kimberly K.; Josefson, Jami; Redman, Leanne M.; Hannah, Wesley; Bonham, Maxine P.; Chen, Mingling; Chivers, Sian C.; Fawcett, Andrea J.; Grieger, Jessica A.; Habibi, Nahal; Leung, Gloria K. W.; Liu, Kai; Mekonnen, Eskedar G.; Pathirana, Maleesa; Quinteros, Alejandra; Taylor, Rachael; Ukke, Gebresilasea G.; Zhou, Shao J.; Franks, Paul W.; Rich, Stephen S.; Wagner, Robert; Vilsbøll, Tina; Udler, Miriam S.; Tuomi, Tiinamaija; Sweeting, Arianne; Sims, Emily K.; Sherr, Jennifer L.; Semple, Robert K.; Reynolds, Rebecca M.; Redondo, Maria J.; Pratley, Richard E.; Pop-Busui, Rodica; Pollin, Toni I.; Perng, Wei; Pearson, Ewan R.; Ozanne, Susan E.; Owen, Katharine R.; Oram, Richard; Murphy, Rinki; Mohan, Viswanathan; Misra, Shivani; Meigs, James B.; Mathioudakis, Nestoras; Mathieu, Chantal; Ma, Ronald C. W.; Loos, Ruth J. F.; Lim, Siew S.; Laffel, Lori M.; Kwak, Soo Heon; Josefson, Jami L.; Hood, Korey K.; Hivert, Marie-France; Hirsch, Irl B.; Hattersley, Andrew T.; Griffin, Kurt; Greeley, Siri Atma W.; Gottlieb, Peter A.; Gomez, Maria F.; Gloyn, Anna L.; Florez, Jose C.; Dennis, John M.; Costacou, Tina; Boyle, Kristen; Billings, Liana K.; Brown, Rebecca J.; Philipson, Louis H.; Nolan, John J.; Eckel, Robert H.; Sherifali, Diana; Mixter, Emily; Mekonnen, Eskedar Getie; Gruber, Chandra; Fawcett, Andrea J.; de Souza, Russell; Auh, Sungyoung; Zhu, Yeyi; Zhang, Cuilin; Saint-Martin, Cécile; Provenzano, Michele; Pomares-Millan, Hugo; Njølstad, Pål Rasmus; Nakabuye, Mariam; Molnes, Janne; McGovern, Andrew; Maloney, Kristin A.; Flanagan, Sarah E.; de Franco, Elisa; Aukrust, Ingvild; Polak, Michel; Beltrand, Jacques; Zhang, Yingchai; Yu, Gechang; White, Sara L.; Hannah, Wesley; Wentworth, John M.; Vatier, Camille; Van der Schueren, Bart; Urazbayeva, Marzhan; Ukke, Gebresilasea Gendisha; Tye, Sok Cin; Støy, Julie; Stefan, Norbert; Steck, Andrea K.; Steenackers, Nele; Stanislawski, Maggie A.; Speake, Cate; Sheu, Wayne Huey-Herng; Selvin, Elizabeth; Scholtens, Denise M.; Monaco, Gabriela S. F.; Sarkar, Sudipa; Kanbour, Sarah; Santhakumar, Vanessa; Saeed, Zeb; Ried-Larsen, Mathias; Ray, Debashree; Jain, Rashmi; Powe, Camille E.; Petrie, John R.; Perez, Dianna; Pazmino, Sofia; Pankow, James S.; Onengut-Gumuscu, Suna; Motala, Ayesha A.; Morton, Robert W.; Lowe, William L.; Long, S. Alice; Libman, Ingrid M.; Leong, Aaron; Koivula, Robert W.; Jones, Angus G.; Johnson, Randi K.; Hoag, Benjamin; Ismail, Heba M.; Harris-Kawano, Arianna; Huang, Chuiguo; Hansen, Torben; Guasch-Ferré, Marta; Grieger, Jessica A.; Goodarzi, Mark O.; Gitelman, Stephen E.; Fitzpatrick, Stephanie L.; Fitipaldi, Hugo; Fernández-Balsells, María Mercè; Evans-Molina, Carmella; Dudenhöffer-Pfeifer, Monika; DiMeglio, Linda A.; Dickens, Laura T.; Deutsch, Aaron J.; Dawed, Adem Y.; Dabelea, Dana; Clemmensen, Christoffer; Chikowore, Tinashe; Cheng, Feifei; Andersen, Mette K.; Amouyal, Chloé; Young, Katherine; Yamamoto, Jennifer M.; Wong, Jessie J.; Wang, Caroline C.; Wallace, Amelia S.; Tosur, Mustafa; Thuesen, Anne Cathrine B.; Tam, Claudia Ha-ting; Sevilla-Gonzalez, Magdalena; Semnani-Azad, Zhila; Schön, Martin; Rooney, Mary R.; Raghavan, Sridharan; Prystupa, Katsiaryna; Pilla, Scott J.; Patel, Kashyap Amratlal; Ozkan, Bige; Naylor, Rochelle N.; Most, Jasper; Morieri, Mario Luca; Miller, Rachel G.; Mclennan, Niamh-Maire; Massey, Robert; Männistö, Jonna M. E.; Lim, Lee-Ling; Kreienkamp, Raymond J.; Kettunen, Jarno L. T.; Kahkoska, Anna R.; Jacobsen, Laura M.; Ikle, Jennifer M.; Hughes, Alice; Haider, Eram; Gaillard, Romy; Gingras, Véronique; Gillard, Pieter; Francis, Ellen C.; Felton, Jamie L.; Duan, Daisy; Cromer, Sara J.; Corcoy, Rosa; Colclough, Kevin; Clark, Amy L.; Bodhini, Dhanasekaran; Benham, Jamie L.; Svalastoga, Pernille; Aiken, Catherine; Ahmad, Abrar; Merino, Jordi; Tobias, Deirdre K.; Lim, Siew (Journal article; Peer reviewed, 2024)
      Background: Lifestyle choices, metformin, and dietary supplements may prevent GDM, but the effect of intervention characteristics has not been identified. This review evaluated intervention characteristics to inform the ...

    • Functional Analyses of Rare Germline Missense BRCA1 Variants Located within and outside Protein Domains with Known Functions 

      Hovland, Henrikke Nilsen; Mchaina, Eunice Kabanyana; Vetti, Hildegunn Høberg; Ariansen, Sarah Louise; Sjursen, Wenche; Van Ghelue, Marijke; Haukanes, Bjørn Ivar; Knappskog, Per Morten; Aukrust, Ingvild; Berge, Elisabet Ognedal (Journal article; Peer reviewed, 2023-01-19)
      The BRCA1 protein is implicated in numerous important cellular processes to prevent genomic instability and tumorigenesis, and pathogenic germline variants predispose carriers to hereditary breast and ovarian cancer (HBOC). ...

    • Functional Characterization of ABCA4 Missense Variants Aids Variant Interpretation and Phenotype Prediction in Patients With ABCA4-Retinal Dystrophies 

      Aslaksen, Sigrid; Aukrust, Ingvild; Molday, Laurie; Holtan, Josephine Prener; Jansson, Ragnhild Wivestad; Berland, Siren; Rødahl, Eyvind; Bredrup, Cecilie; Bragadottir, Ragnheidur; Bratland, Eirik; Molday, Robert S.; Knappskog, Per Morten (Journal article; Peer reviewed, 2024)
      Purpose: Biallelic pathogenic variants in the gene encoding the ATP-binding cassette transporter ABCA4 are the leading cause of irreversible vision loss in inherited retinal dystrophies (IRDs). Interpretation of ABCA4 ...

    • Functional characterization of HNF4A gene variants identify promoter and cell line specific transactivation effects 

      Kaci, Alba; Solheim, Marie Holm; Silgjerd, Trine; Hjaltadottir, Jorunn; Hornnes, Lorentze Hope; Molnes, Janne; Madsen, Andre Greger; Sjøholt, Gry; Bellanne-Chantelot, Christine; Caswell, Richard; Sagen, Jørn Vegard; Njølstad, Pål Rasmus; Aukrust, Ingvild; Bjørkhaug, Lise (Journal article; Peer reviewed, 2024)
      Hepatocyte nuclear factor-4 alpha (HNF-4A) regulates genes with roles in glucose metabolism and β-cell development. Although pathogenic HNF4A variants are commonly associated with maturity-onset diabetes of the young (MODY1; ...

    • Functional evaluation of 16 SCHAD missense variants: Only amino acid substitutions causing congenital hyperinsulinism of infancy lead to loss-of-function phenotypes in vitro 

      Velasco Pinto, Kelly; St-Louis, Johanna; Hovland, Henrikke N.; Thompson, Nels; Ottesen, Åsta; Choi, Man Hung; Pedersen, Line; Njølstad, Pål Rasmus; Arnesen, Thomas; Fjeld, Karianne; Aukrust, Ingvild; Myklebust, Line Merethe; Molven, Anders (Journal article; Peer reviewed, 2021)
      Short‐chain 3‐hydroxyacyl‐CoA dehydrogenase (SCHAD), encoded by the HADH gene, is a ubiquitously expressed mitochondrial enzyme involved in fatty acid oxidation. This protein also plays a role in insulin secretion as ...

    • Genetic Dominant Variants in STUB1, Segregating in Families with SCA48, Display In Vitro Functional Impairments Indistinctive from Recessive Variants Associated with SCAR16 

      Pakdaman, Yasaman; Berland, Siren; Bustad, Helene J.; Erdal, Sigrid; Thompson, Bryony A.; James, Paul A.; Power, Kjersti; Ellingsen, Ståle; Krooni, Martin; Berge, Line Iden; Sexton, Adrienne; Bindoff, Laurence Albert; Knappskog, Per Morten; Johansson, Stefan; Aukrust, Ingvild (Journal article; Peer reviewed, 2021)
      Variants in STUB1 cause both autosomal recessive (SCAR16) and dominant (SCA48) spinocerebellar ataxia. Reports from 18 STUB1 variants causing SCA48 show that the clinical picture includes later-onset ataxia with a cerebellar ...

    • In vitro characterization of six STUB1 variants in spinocerebellar ataxia 16 reveals altered structural properties for the encoded CHIP proteins 

      Pakdaman, Yasaman; Sanchez Guixe, Monica; Kleppe, Rune; Erdal, Sigrid; Bustad, Helene J.; Bjørkhaug, Lise; Haugarvoll, Kristoffer; Tzoulis, Charalampos; Heimdal, Ketil Riddervold; Knappskog, Per; Johansson, Stefan; Aukrust, Ingvild (Peer reviewed; Journal article, 2017)
      Spinocerebellar ataxia, autosomal recessive 16 (SCAR16) is caused by biallelic mutations in the STIP1 homology and U-box containing protein 1 (STUB1) gene encoding the ubiquitin E3 ligase and dimeric co-chaperone C-terminus ...

    • Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review 

      Felton, Jamie L.; Redondo, Maria J.; Oram, Richard A.; Speake, Cate; Long, S. Alice; Onengut-Gumuscu, Suna; Rich, Stephen S.; Monaco, Gabriela S. F.; Harris-Kawano, Arianna; Perez, Dianna; Saeed, Zeb; Hoag, Benjamin; Jain, Rashmi; Evans-Molina, Carmella; DiMeglio, Linda A.; Ismail, Heba M.; Dabelea, Dana; Johnson, Randi K.; Urazbayeva, Marzhan; Wentworth, John M.; Griffin, Kurt J.; Sims, Emily K.; Franks, Paul W.; Rich, Stephen S.; Wagner, Robert; Vilsbøll, Tina; Vesco, Kimberly K.; Udler, Miriam S.; Tuomi, Tiinamaija; Sweeting, Arianne; Sims, Emily K.; Sherr, Jennifer L.; Semple, Robert K.; Reynolds, Rebecca M.; Redman, Leanne M.; Pratley, Richard E.; Pop-Busui, Rodica; Pollin, Toni I.; Perng, Wei; Pearson, Ewan R.; Ozanne, Susan E.; Owen, Katharine R.; Oram, Richard; Murphy, Rinki; Mohan, Viswanathan; Misra, Shivani; Meigs, James B.; Mathioudakis, Nestoras; Mathieu, Chantal; Ma, Ronald C. W.; Loos, Ruth J. F.; Lim, Siew S.; Laffel, Lori M.; Kwak, Soo Heon; Josefson, Jami L.; Hood, Korey K.; Hivert, Marie-France; Hirsch, Irl B.; Hattersley, Andrew T.; Griffin, Kurt; Greeley, Siri Atma W.; Gottlieb, Peter A.; Gomez, Maria F.; Gloyn, Anna L.; Florez, Jose C.; Dennis, John M.; Costacou, Tina; Boyle, Kristen; Billings, Liana K.; Brown, Rebecca J.; Philipson, Louis H.; Nolan, John J.; Eckel, Robert H.; Sherifali, Diana; Mixter, Emily; Mekonnen, Eskedar Getie; Gruber, Chandra; Fawcett, Andrea J.; de Souza, Russell; Auh, Sungyoung; Zhu, Yeyi; Zhang, Cuilin; Saint-Martin, Cécile; Provenzano, Michele; Pomares-Millan, Hugo; Njølstad, Pål Rasmus; Nakabuye, Mariam; Molnes, Janne; McGovern, Andrew; Maloney, Kristin A.; Flanagan, Sarah E.; de Franco, Elisa; Aukrust, Ingvild; Polak, Michel; Beltrand, Jacques; Zhou, Shao J.; Zhang, Yingchai; Yu, Gechang; White, Sara L.; Hannah, Wesley; Vatier, Camille; Van der Schueren, Bart; Ukke, Gebresilasea Gendisha; Tye, Sok Cin; Taylor, Rachael; Støy, Julie; Stefan, Norbert; Steck, Andrea K.; Steenackers, Nele; Stanislawski, Maggie A.; Sheu, Wayne Huey-Herng; Selvin, Elizabeth; Scholtens, Denise M.; Sarkar, Sudipa; Kanbour, Sarah; Santhakumar, Vanessa; Ried-Larsen, Mathias; Ray, Debashree; Quinteros, Alejandra; Powe, Camille E.; Petrie, John R.; Perez, Dianna; Pazmino, Sofia; Pathirana, Maleesa; Pankow, James S.; Onengut-Gumuscu, Suna; Motala, Ayesha A.; Morton, Robert W.; Lowe, William L.; Liu, Kai; Libman, Ingrid M.; Leung, Gloria K. W.; Leong, Aaron; Koivula, Robert W.; Jones, Angus G.; Huang, Chuiguo; Hansen, Torben; Habibi, Nahal; Guasch-Ferré, Marta; Grieger, Jessica A.; Goodarzi, Mark O.; Gitelman, Stephen E.; Fitzpatrick, Stephanie L.; Fitipaldi, Hugo; Fernández-Balsells, María Mercè; Dudenhöffer-Pfeifer, Monika; DiMeglio, Linda A.; Dickens, Laura T.; Deutsch, Aaron J.; Dawed, Adem Y.; Clemmensen, Christoffer; Chivers, Sian C.; Chikowore, Tinashe; Cheng, Feifei; Chen, Mingling; Bonham, Maxine P.; Andersen, Mette K.; Amouyal, Chloé; Young, Katherine; Yamamoto, Jennifer M.; Wong, Jessie J.; Wang, Caroline C.; Wallace, Amelia S.; Tosur, Mustafa; Thuesen, Anne Cathrine B.; Tam, Claudia Ha-ting; Takele, Wubet Worku; Sevilla-Gonzalez, Magdalena; Semnani-Azad, Zhila; Schön, Martin; Rooney, Mary R.; Raghavan, Sridharan; Prystupa, Katsiaryna; Pilla, Scott J.; Patel, Kashyap Amratlal; Ozkan, Bige; Naylor, Rochelle N.; Most, Jasper; Morieri, Mario Luca; Miller, Rachel G.; Mclennan, Niamh-Maire; Massey, Robert; Männistö, Jonna M. E.; Lim, Lee-Ling; Kreienkamp, Raymond J.; Kettunen, Jarno L. T.; Kahkoska, Anna R.; Jacobsen, Laura M.; Ikle, Jennifer M.; Hughes, Alice; Haider, Eram; Gaillard, Romy; Gingras, Véronique; Gillard, Pieter; Francis, Ellen C.; Felton, Jamie L.; Duan, Daisy; Cromer, Sara J.; Corcoy, Rosa; Colclough, Kevin; Clark, Amy L.; Bodhini, Dhanasekaran; Benham, Jamie L.; Aiken, Catherine; Ahmad, Abrar; Merino, Jordi; Tobias, Deirdre K.; Svalastoga, Pernille (Journal article; Peer reviewed, 2024)
      Background Islet autoantibodies form the foundation for type 1 diabetes (T1D) diagnosis and staging, but heterogeneity exists in T1D development and presentation. We hypothesized that autoantibodies can identify ...

    • NAA10 dysfunction with normal NatA-complex activity in a girl with non-syndromic ID and a de novo NAA10 p.(V111G) variant - a case report 

      Mc Tiernan, Nina; Støve, Svein Isungset; Aukrust, Ingvild; Mårli, Marita Torrissen; Myklebust, Line Merethe; Houge, Gunnar; Arnesen, Thomas (Peer reviewed; Journal article, 2018)
      Background: The NAA10-NAA15 (NatA) protein complex is an N-terminal acetyltransferase responsible for acetylating ~ 40% of eukaryotic proteins. In recent years, NAA10 variants have been found in patients with an X-linked ...

    • A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland 

      Thuesen, Anne Cathrine; Stæger, Fredrik Filip; Kaci, Alba; Solheim, Marie Holm; Aukrust, Ingvild; Jørsboe, Emil; Santander, Cindy G.; Andersen, Mette; Li, Zilong; Gilly, Arthur; Stinson, Sara Elizabeth; Gjesing, Anette Prior; Bjerregaard, Peter; Pedersen, Michael Lynge; Larsen, Christina Viskum Lytken; Grarup, Niels; Jørgensen, Marit E.; Zeggini, Eleftheria; Bjørkhaug, Lise; Njølstad, Pål Rasmus; Albrechtsen, Anders; Moltke, Ida; Hansen, Torben (Journal article; Peer reviewed, 2023)
      Background: The genetic disease architecture of Inuit includes a large number of common high-impact variants. Identification of such variants contributes to our understanding of the genetic aetiology of diseases and improves ...

    • Post-translational modifications of Annexin A2 are linked to its association with perinuclear nonpolysomal mRNP complexes 

      Aukrust, Ingvild; Rosenberg, Linn Andersen; Ankerud, Mia Madeleine; Bertelsen, Vibeke; Hollås, Hanne; Saraste, Jaakko; Grindheim, Ann Kari; Vedeler, Anni (Peer reviewed; Journal article, 2017-02)
      Various post-translational modifications (PTMs) regulate the localisation and function of the multifunctional protein Annexin A2 (AnxA2). In addition to its various tasks as a cytoskeletal- and membrane-associated protein, ...

    • Precision prognostics for cardiovascular disease in Type 2 diabetes: a systematic review and meta-analysis 

      Ahmad, Abrar; Lim, Lee-Ling; Morieri, Mario Luca; Tam, Claudia Ha-ting; Cheng, Feifei; Chikowore, Tinashe; Dudenhöffer-Pfeifer, Monika; Fitipaldi, Hugo; Huang, Chuiguo; Kanbour, Sarah; Sarkar, Sudipa; Koivula, Robert Wilhelm; Motala, Ayesha A.; Tye, Sok Cin; Yu, Gechang; Zhang, Yingchai; Provenzano, Michele; Sherifali, Diana; de Souza, Russell J.; Tobias, Deirdre Kay; Franks, Paul W.; Rich, Stephen S.; Wagner, Robert; Vilsbøll, Tina; Vesco, Kimberly K.; Udler, Miriam S.; Tuomi, Tiinamaija; Sweeting, Arianne; Sims, Emily K.; Sherr, Jennifer L.; Semple, Robert K.; Reynolds, Rebecca M.; Redondo, Maria J.; Redman, Leanne M.; Pratley, Richard E.; Pop-Busui, Rodica; Pollin, Toni I.; Perng, Wei; Pearson, Ewan R.; Ozanne, Susan E.; Owen, Katharine R.; Oram, Richard; Murphy, Rinki; Mohan, Viswanathan; Misra, Shivani; Meigs, James B.; Mathioudakis, Nestoras; Mathieu, Chantal; Ma, Ronald C. W.; Loos, Ruth J. F.; Lim, Siew S.; Laffel, Lori M.; Kwak, Soo Heon; Josefson, Jami L.; Hood, Korey K.; Hivert, Marie-France; Hirsch, Irl B.; Hattersley, Andrew T.; Griffin, Kurt; Greeley, Siri Atma W.; Gottlieb, Peter A.; Gloyn, Anna L.; Florez, Jose C.; Dennis, John M.; Costacou, Tina; Boyle, Kristen; Billings, Liana K.; Brown, Rebecca J.; Philipson, Louis H.; Nolan, John J.; Eckel, Robert H.; Mixter, Emily; Mekonnen, Eskedar Getie; Gruber, Chandra; Fawcett, Andrea J.; de Souza, Russell; Auh, Sungyoung; Zhu, Yeyi; Zhang, Cuilin; Saint-Martin, Cécile; Pomares-Millan, Hugo; Njølstad, Pål Rasmus; Nakabuye, Mariam; Molnes, Janne; McGovern, Andrew; Maloney, Kristin A.; Flanagan, Sarah E.; de Franco, Elisa; Aukrust, Ingvild; Polak, Michel; Beltrand, Jacques; Zhou, Shao J.; White, Sara L.; Hannah, Wesley; Wentworth, John M.; Vatier, Camille; Van der Schueren, Bart; Urazbayeva, Marzhan; Ukke, Gebresilasea Gendisha; Taylor, Rachael; Støy, Julie; Stefan, Norbert; Steck, Andrea K.; Steenackers, Nele; Stanislawski, Maggie A.; Speake, Cate; Sheu, Wayne Huey-Herng; Selvin, Elizabeth; Scholtens, Denise M.; Monaco, Gabriela S. F.; Santhakumar, Vanessa; Saeed, Zeb; Ried-Larsen, Mathias; Ray, Debashree; Jain, Rashmi; Quinteros, Alejandra; Powe, Camille E.; Petrie, John R.; Perez, Dianna; Pazmino, Sofia; Pathirana, Maleesa; Pankow, James S.; Onengut-Gumuscu, Suna; Morton, Robert W.; Lowe, William L.; Long, S. Alice; Liu, Kai; Libman, Ingrid M.; Leung, Gloria K. W.; Leong, Aaron; Koivula, Robert W.; Jones, Angus G.; Johnson, Randi K.; Hoag, Benjamin; Ismail, Heba M.; Harris-Kawano, Arianna; Hansen, Torben; Habibi, Nahal; Guasch-Ferré, Marta; Grieger, Jessica A.; Goodarzi, Mark O.; Gitelman, Stephen E.; Fitzpatrick, Stephanie L.; Fernández-Balsells, María Mercè; Evans-Molina, Carmella; DiMeglio, Linda A.; Dickens, Laura T.; Deutsch, Aaron J.; Dawed, Adem Y.; Dabelea, Dana; Clemmensen, Christoffer; Chivers, Sian C.; Chen, Mingling; Bonham, Maxine P.; Andersen, Mette K.; Amouyal, Chloé; Young, Katherine; Yamamoto, Jennifer M.; Wong, Jessie J.; Wang, Caroline C.; Wallace, Amelia S.; Tosur, Mustafa; Thuesen, Anne Cathrine B.; Takele, Wubet Worku; Svalastoga, Pernille; Sevilla-Gonzalez, Magdalena; Semnani-Azad, Zhila; Schön, Martin; Rooney, Mary R.; Raghavan, Sridharan; Prystupa, Katsiaryna; Pilla, Scott J.; Patel, Kashyap Amratlal; Ozkan, Bige; Naylor, Rochelle N.; Most, Jasper; Miller, Rachel G.; Mclennan, Niamh-Maire; Massey, Robert; Männistö, Jonna M. E.; Lim, Lee-Ling; Kreienkamp, Raymond J.; Kettunen, Jarno L. T.; Kahkoska, Anna R.; Jacobsen, Laura M.; Ikle, Jennifer M.; Hughes, Alice; Haider, Eram; Gaillard, Romy; Gingras, Véronique; Gillard, Pieter; Francis, Ellen C.; Felton, Jamie L.; Duan, Daisy; Cromer, Sara J.; Corcoy, Rosa; Colclough, Kevin; Clark, Amy L.; Bodhini, Dhanasekaran; Benham, Jamie L.; Aiken, Catherine; Merino, Jordi; Tobias, Deirdre K.; Gomez, Maria F.; Mathioudakis, Nestoras (Journal article; Peer reviewed, 2024)
      Background Precision medicine has the potential to improve cardiovascular disease (CVD) risk prediction in individuals with Type 2 diabetes (T2D). Methods We conducted a systematic review and meta-analysis of ...