Browsing Bergen Open Research Archive by Author "Azeem, Waqas"
Now showing items 1-3 of 3
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Context dependent regulatory patterns of the androgen receptor and androgen receptor target genes
Olsen, Jan R; Azeem, Waqas; Hellem, Margrete R; Marvyin, Kristo; Hua, Yaping; Qu, Yi; Li, Lisha; Lin, Biaoyang; Ke, XI- S; Øyan, Anne Margrete; Kalland, Karl-Henning (Peer reviewed; Journal article, 2016-07-04)Background Expression of the androgen receptor (AR) is associated with androgen-dependent proliferation arrest and terminal differentiation of normal prostate epithelial cells. Additionally, activation of the AR is required ... -
Evaluation of β-catenin inhibition of axitinib and nitazoxanide in human monocyte-derived dendritic cells
Azeem, Waqas; Bakke, Ragnhild Maukon; Gabriel, Benjamin; Appel, Silke; Øyan, Anne Margrete; Kalland, Karl-Henning (Journal article; Peer reviewed, 2021)Modulation of β-catenin signaling has attractive therapeutic potential in cancer immunotherapy. Several studies have found that β-catenin can mediate immune evasion in cancer and promote anti-inflammatory features of ... -
Proteasome‐mediated regulation of GATA2 expression and androgen receptor transcription in benign prostate epithelial cells
Azeem, Waqas; Olsen, Jan Roger; Hellem, Margrete Reime; Hua, Yaping; Marvyin, Kristo; Ke, Xisong; Øyan, Anne Margrete; Kalland, Karl Henning (Journal article; Peer reviewed, 2022)GATA2 has been shown to be an important transcription factor together with androgen receptor (AR) in prostate cancer cells. Less is known about GATA2 in benign prostate epithelial cells. We have investigated if GATA2 ...