Blar i Bergen Open Research Archive på forfatter "Bakke, Per S."

Viser treff 1-20 av 41

    • Acute exacerbations of COPD and risk of lung cancer in COPD patients with and without a history of asthma 

      Gagnat, Ane Aamli; Gjerdevik, Miriam; Lie, Stein Atle; Gulsvik, Amund; Bakke, Per S.; Nielsen, Rune (Journal article; Peer reviewed, 2020)
      Rationale There is limited knowledge on the effect of acute exacerbations in chronic obstructive pulmonary disease (AECOPD) on lung cancer risk in COPD patients with and without a history of asthma. This study aims to ...

    • Association of the FAM46A gene VNTRs and BAG6 rs3117582 SNP with non small cell lung cancer (NSCLC) in Croatian and Norwegian populations 

      Etokebe, Godfrey; Zienolddiny, Shanbeh; Kupanovac, Zeljko; Enersen, Morten; Balen, Sanja; Flego, Velkjo; Bulat-Kardum, Ljiljana; Radojčić-Badovinac, Anđelka; Skaug, Vidar; Bakke, Per S.; Haugen, Aage; Dembic, Zlatko (Peer reviewed; Journal article, 2015-04-17)
      We analyzed for associations between a variable number of tandem repeat (VNTR) polymorphism in the Family with sequence similarity 46, member A (FAM46A) gene and a single nucleotide polymorphism (rs3117582) in the ...

    • The association of tidal EFL with exercise performance, exacerbations, and death in COPD 

      Aarli, Bernt Bøgvald; Calverley, Peter M.A.; Jensen, Robert L.; Dellacà, Raffaele; Eagan, Tomas Mikal; Bakke, Per S.; Hardie, Jon Andrew (Peer reviewed; Journal article, 2017-07-26)
      Background: Tidal expiratory flow limitation (EFLT) is frequently found in patients with COPD and can be detected by forced oscillations when within-breath reactance of a single-breath is ≥0.28 kPa·s·L-1. The present study ...

    • Change in pulmonary diffusion capacity in a general population sample over 9 years 

      Storebø, Michael Langballe; Eagan, Tomas Mikal; Eide, Geir Egil; Gulsvik, Amund; Thorsen, Einar; Bakke, Per S. (Peer reviewed; Journal article, 2016-09-02)
      Rationale: Data on the change in diffusion capacity of the lung for carbon monoxide (DLCO) over time are limited. We aimed to examine change in DLCO (ΔDLCO) over a 9-year period and its predictors. Methods: A Norwegian ...

    • Change in pulmonary diffusion capacity in a general population sample over 9 years 

      Storebø, Michael Langballe; Eagan, Tomas Mikal; Eide, Geir Egil; Gulsvik, Amund; Thorsen, Einar; Bakke, Per S. (Peer reviewed; Journal article, 2016-09-02)
      Rationale: Data on the change in diffusion capacity of the lung for carbon monoxide (DL_CO) over time are limited. We aimed to examine change in DL_CO (ΔDL_CO) over a 9-year period and its predictors. Methods: A Norwegian ...

    • Comparing microbiota profiles in induced and spontaneous sputum samples in COPD patients 

      Tangedal, Solveig; Aanerud, Marianne; Grønseth, Rune; Drengenes, Christine; Wiker, Harald G; Bakke, Per S.; Eagan, Tomas Mikal (Peer reviewed; Journal article, 2017-08-29)
      Background: Induced and spontaneous sputum are used to evaluate the airways microbiota. Whether the sputum types can be used interchangeably in microbiota research is unknown. Our aim was to compare microbiota in induced ...

    • Comparison of inflammatory markers in induced and spontaneous sputum in a cohort of COPD patients 

      Tangedal, Solveig; Aanerud, Marianne; Persson, Louise Jeanette Pauline; Brokstad, Karl Albert; Bakke, Per S.; Eagan, Tomas Mikal (Peer reviewed; Journal article, 2014-11-15)
      Background: Sputum induction is a non-invasive method for obtaining measurements of inflammation in the airways. Whether spontaneously sampled sputum can be a valid surrogate is unknown. The aim of this study was to compare ...

    • Complications and discomfort after research bronchoscopy in the MicroCOPD study 

      Leiten, Elise Orvedal; Eagan, Tomas Mikal; Martinsen, Einar Marius Hjellestad; Nordeide, Eli; Husebø, Gunnar; Knudsen, Kristel Svalland; Lehmann, Sverre; Svanes, Øistein; Bakke, Per S.; Nielsen, Rune (Journal article; Peer reviewed, 2020)
      Background: Data on discomfort and complications from research bronchoscopy in chronic obstructive pulmonary disease (COPD) and asthma is limited. We present complications and discomfort occurring within a week after ...

    • Complications and discomfort of bronchoscopy: a systematic review 

      Leiten, Elise Orvedal; Martinsen, Einar Marius Hjellestad; Eagan, Tomas Mikal; Bakke, Per S.; Grønseth, Rune (Peer reviewed; Journal article, 2016)
      Objective: To identify bronchoscopy-related complications and discomfort, meaningful complication rates, and predictors. Method: We conducted a systematic literature search in PubMed on 8 February 2016, using a search ...

    • Dynamic differences in dietary polyunsaturated fatty acid metabolism in sputum of COPD patients and controls 

      van der Does, Anne M; Heijink, Marieke; Mayboroda, Oleg A.; Persson, Louise Jeanette Pauline; Aanerud, Marianne; Bakke, Per S.; Eagan, Tomas Mikal; Hiemstra, Pieter S.; Giera, Martin (Peer reviewed; Journal article, 2019)
      Introduction: Disturbances in onset and resolution of inflammation in chronic obstructive pulmonary disease (COPD) are incompletely understood. Dietary polyunsaturated fatty acids (PUFAs) can be converted into lipid mediators ...

    • Efficacy and safety of 4 weeks' treatment with combined fluticasone furoate/vilanterol in a single inhaler given once daily in COPD: a placebo-controlled randomised trial 

      Lotvall, J; Bakke, Per S.; Bjermer, Leif; Steinshamn, Sigurd Loe; Scott-Wilson, C; Crim, Courtney; Sanford, L; Haumann, B (Peer reviewed; Journal article, 2012-01-19)
      Background. Fluticasone furoate/vilanterol (FF/VI) is a novel once-daily (OD) inhaled corticosteroid/long-acting β2 agonist combination in development for chronic obstructive pulmonary disease (COPD) and asthma. Trial ...

    • Factors associated with coronary heart disease in COPD patients and controls 

      Svendsen, Christina D.; Kuiper, Karel Kier-Jan; Ostridge, Kristoffer; Larsen, Terje Hjalmar; Nielsen, Rune; Hodneland, Vidar; Nordeide, Eli; Bakke, Per S.; Eagan, Tomas Mikal Lind (Journal article; Peer reviewed, 2022-04-27)
      Background: COPD and coronary heart disease (CHD) frequently co-occur, yet which COPD phenotypes are most prone to CHD is poorly understood. The aim of this study was to see whether COPD patients did have a true higher ...

    • Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development 

      Li, Yafang; Xiao, Xiangjun; Bossé, Yohan; Gorlova, Olga; Gorlov, Ivan; Han, Younghun; Byun, Jinyoung; Leighl, Natasha; Johansen, Jakob S.; Barnett, Matt; Chen, Chu; Goodman, Gary; Cox, Angela; Taylor, Fiona; Woll, Penella; Wichmann, Erich; Manz, Judith; Muley, Thomas; Risch, Angela; Rosenberger, Albert; Han, Jiali; Siminovitch, Katherine; Arnold, Susanne; Haura, Eric B.; Bolca, Ciprian; Holcátová, Ivana; Janout, Vladimir; Kontic, Milica; Lissowska, Jolanta; Mukeria, Anush; Ognjanovic, Simona; Orlowski, Tadeusz M.; Scelo, Ghislaine; Swiatkowska, Beata; Zaridze, David; Bakke, Per S.; Skaug, Vidar; Zienolddiny, Shanbeh; Duell, Eric J.; Butler, Lesley M.; Houlston, Richard; Artigas, Maria Soler; Grankvist, Kjell; Johansson, Mikael; Shepherd, Frances A.; Marcus, Michael; Brunnström, Hans; Manjer, Jonas; Melander, Olle; Muller, David C.; Overvad, Kim; Trichopoulou, Antonia; Tumino, Rosaria; Liu, Geoffrey; Bojesen, Stig; Wu, Xifeng; Le Marchand, Loic; Albanes, Demetrios; Bickeböller, Heike; Aldrich, Melinda C.; Bush, William S.; Tardon, Adonina; Rennert, Gad; Teare, M. Dawn; Field, John K.; Kiemeney, Lambertus A.; Lazarus, Philip; Haugen, Aage; Lam, Stephen; Schabath, Matthew B.; Andrew, Angeline S.; Bertazzi, Pier Alberto; Pesatori, Angela C.; Christiani, David C.; Caporaso, Neil; Johansson, Mattias; McKay, James D.; Brennan, Paul; Hung, Rayjean J.; Amos, Christopher I. (Peer reviewed; Journal article, 2019)
      The development of cancer is driven by the accumulation of many oncogenesis-related genetic alterationsand tumorigenesis is triggered by complex networks of involved genes rather than independent actions. To explore the ...

    • A genome-wide association study in chronic obstructive pulmonary disease (COPD): Identification of two major susceptibility loci 

      Pillai, Sreekumar G.; Ge, Dongliang; Zhu, Guohua; Kong, Xiangyang; Shianna, Kevin V.; Need, Anna C.; Feng, Sheng; Hersh, Craig P.; Bakke, Per S.; Gulsvik, Amund; Ruppert, Andreas; Carlsen, Karin Cecilie Lødrup; Roses, Allen; Anderson, Wayne; Rennard, Stephen I.; Lomas, David A.; Silverman, Edwin K.; Goldstein, David B. (Peer reviewed; Journal article, 2009-03-20)
      There is considerable variability in the susceptibility of smokers to develop chronic obstructive pulmonary disease (COPD). The only known genetic risk factor is severe deficiency of α1-antitrypsin, which is present in ...

    • A genome-wide association study of bronchodilator response in participants of European and African ancestry from six independent cohorts 

      Gereige, Jessica D.; Xu, Hanfei; Ortega, Victor E.; Cho, Michael H.; Liu, Ming; Sakornsakolpat, Phuwanat; Silverman, Edwin K.; Beaty, Terri H.; Miller, Bruce E.; Bakke, Per S.; Gulsvik, Amund; Hersh, Craig P.; Morrow, Jarrett D.; Ampleford, Elizabeth J.; Hawkins, Gregory A.; Bleecker, Eugene R.; Meyers, Deborah A.; Peters, Stephen P.; Celedón, Juan C.; Tantisira, Kelan; Li, Jiang; Dupuis, Josée; O’connor, George T. (Journal article; Peer reviewed, 2022)
      Introduction Bronchodilator response (BDR) is a measurement of acute bronchodilation in response to short-acting β2-agonists, with a heritability between 10 and 40%. Identifying genetic variants associated with BDR may ...

    • Global Lung Function Initiative 2012 reference equations for spirometry in the Norwegian Population 

      Langhammer, Arnulf; Johannessen, Ane; Holmen, Turid Lingaas; Melbye, Hasse; Stanojevic, Sanja; Lund, May Brit; Melsom, Morten Nissen; Bakke, Per S.; Quanjer, Philip (Peer reviewed; Journal article, 2016)
      We studied the fit of the Global Lung Function Initiative (GLI) all-age reference values to Norwegians, compared them with currently used references (European Community for Steel and Coal (ECSC) and Zapletal) and estimated ...

    • Identification of susceptibility pathways for the roleof chromosome 15q25.1 in modifying lung cancerrisk 

      Ji, Xuemei; Bossé, Yohan; Landi, Maria Teresa; Gui, Jiang; Xiao, Xiangjun; Qian, David C; Joubert, Philippe; Lamontagne, Maxime; Li, Yafang; Gorlov, Ivan; de Biasi, Mariella; Han, Younghun; Gorlova, Olga; Hung, Rayjean J.; Wu, Xifeng; McKay, James; Zong, Xuchen; Carreras-Torres, Robert; Christiani, David C.; Caporaso, Neil; Johansson, Mattias; Liu, Geoffrey; Bojesen, Stig E.; Le Marchand, Loic; Albanes, Demetrios; Bickeboller, Heike; Aldrich, Melinda C.; Bush, William S.; Tardon, Adonina; Rennert, Gad; Chen, Chu; Teare, M. Dawn; Field, John K.; Kiemeney, Lambertus A.; Lazarus, Philip; Haugen, Aage; Lam, Stephen; Schabath, Matthew B.; Andrew, Angeline S.; Shen, Hongbing; Hong, Yun-Chul; Yuan, Jian-Min; Bertazzi, Pier A.; Pesatori, Angela C.; Ye, Yuanqing; Diao, Nancy; Su, Li; Zhang, Ruyang; Brhane, Yonathan; Leighl, Natasha; Johansen, Jakob S.; Mellemgaard, Anders; Saliba, Walid; Haiman, Christopher; Wilkens, Lynne; Fernandez-Somoano, Ana; Fernandez-Tardon, Guillermo; van der Heijden, Erik H. F. M.; Kim, Jin Hee; Dai, Juncheng; Hu, Zhibin; Davies, Michael P.A.; Marcus, Michael W.; Brunnström, Hans; Manjer, Jonas; Melander, Olle; Muller, David C.; Overvad, Kim; Trichopoulou, Antonia; Tumino, Rosario; Doherty, Jennifer; Goodman, Gary; Cox, Angela; Taylor, Fiona; Woll, Penella; Brüske, Irene; Manz, Judith; Muley, Thomas; Risch, Angela; Rosenberger, Albert; Grankvist, Kjell; Johansson, Mikael; Shepherd, Frances; Ming-Sound, Tsao; Arnold, Susanne M.; Haura, Eric B.; Bolca, Ciprian; Holcatova, Ivana; Janout, Vladimir; Kontic, Milica; Lissowska, Jolanta; Mukeria, Anush; Ognjanovic, Simona; Orlowski, Tadeusz M.; Scelo, Ghislaine; Swiatkowska, Beata; Zaridze, David; Bakke, Per S.; Skaug, Vidar; Zienolddiny, Shanbeh; Duell, Eric J.; Butler, Lesley M.; Koh, Woon-Puay; Gao, Yu-Tang; Houlston, Richard; McLaughlin, John; Stevens, Victoria; Nickle, David C.; Obeidat, Ma'en; Timens, Wim; Zhu, Bin; Song, Lei; Artigas, María Soler; Tobin, Martin D.; Wain, Louise V.; Gu, Fangyi; Byun, Jinyoung; Kamal, Ahsan; Zhu, Dakai; Tyndale, Rachel F.; Wei, Wei-Qi; Chanock, Stephen; Brennan, Paul; Amos, Christopher I. (Peer reviewed; Journal article, 2018-08-13)
      Genome-wide association studies (GWAS) identified the chromosome 15q25.1 locus as a leading susceptibility region for lung cancer. However, the pathogenic pathways, through which susceptibility SNPs within chromosome 15q25.1 ...

    • Incidence of utilization- and symptom-defined COPD exacerbations in hospital- and population-recruited patients 

      Erdal, Marta; Johannessen, Ane; Eagan, Tomas Mikal; Bakke, Per S.; Gulsvik, Amund; Grønseth, Rune (Peer reviewed; Journal article, 2016-09)
      Objectives: The objectives of this study were to estimate the impact of recruitment source and outcome definition on the incidence of acute exacerbations of COPD (AECOPD) and explore possible predictors of AECOPD. Patients ...

    • Incremental costs of COPD exacerbations in GOLD stage 2+ COPD in ever-smokers of a general population 

      Erdal, Marta; Johannessen, Ane; Bakke, Per S.; Gulsvik, Amund; Eagan, Tomas Mikal; Nielsen, Rune (Journal article; Peer reviewed, 2020-11)
      Objectives To estimate treatment- and productivity-related costs associated with COPD in two different samples, and to analyse the association between the costs and moderate and severe exacerbations. Methods We performed ...

    • Investigating the rationale for COPD maintenance therapy prescription across Europe, findings from a multi-country study 

      Kocks, Janwillem; Ferreira, António Jorge; Bakke, Per S.; van Schayck, Onno C. P.; Ekroos, Heikki; Tzanakis, Nikolaos; Soulard, Stéphane; Haaksma-Herczegh, Monika; Mestres-Simon, Montserrat; Águila-Fuentes, Malena; Cataldo, Didier (Journal article; Peer reviewed, 2023)
      This study aims to understand healthcare professionals’ thoughts and motivations about optimal management and treatment of patients with chronic obstructive pulmonary disease (COPD). We conducted a DELPHI survey through ...