Browsing Bergen Open Research Archive by Author "Banerjee, Niladri"

Now showing items 1-4 of 4

    • Analysis of differentially methylated regions in great apes and extinct hominids provides support for the evolutionary hypothesis of schizophrenia 

      Banerjee, Niladri; Polushina, Tatiana; Bettella, Francesco; Steen, Vidar Martin; Andreassen, Ole Andreas; Le Hellard, Stephanie (Peer reviewed; Journal article, 2018-12-11)
      Introduction: The persistence of schizophrenia in human populations separated by geography and time led to the evolutionary hypothesis that proposes schizophrenia as a by-product of the higher cognitive abilities of modern ...

    • An evolutionary epigenetics approach to schizophrenia 

      Banerjee, Niladri (Doctoral thesis, 2018-09-28)
      Schizophrenia is a psychotic disorder with an estimated lifetime prevalence of ~1% worldwide. Despite reduced fecundity of patients, this rate is stable across population groups separated by geography and time. There is ...

    • Identification of pleiotropy at the gene level between psychiatric disorders and related traits 

      Polushina, Tatiana; Banerjee, Niladri; Giddaluru, Sudheer; Bettella, Francesco; Espeseth, Thomas; Lundervold, Astri J.; Djurovic, Srdjan; Cichon, Sven; Hoffmann, Per; Nöthen, Markus M.; Steen, Vidar Martin; Andreassen, Ole A.; Le Hellard, Stéphanie (Journal article; Peer reviewed, 2021)
      Major mental disorders are highly prevalent and make a substantial contribution to the global disease burden. It is known that mental disorders share clinical characteristics, and genome-wide association studies (GWASs) ...

    • Recently evolved human-specific methylated regions are enriched in schizophrenia signals 

      Banerjee, Niladri; Polushina, Tatiana; Bettella, Francesco; Giddaluru, Sudheer; Steen, Vidar Martin; Andreassen, Ole Andreas; Le Hellard, Stephanie (Peer reviewed; Journal article, 2018)
      Background: One explanation for the persistence of schizophrenia despite the reduced fertility of patients is that it is a by-product of recent human evolution. This hypothesis is supported by evidence suggesting that ...