Browsing Bergen Open Research Archive by Author "Bedringaas, Siv Lise"

Now showing items 1-2 of 2

4-Alkylated Silver–N-Heterocyclic Carbene (NHC) Complexes with Cytotoxic Effects in Leukemia Cells

Sandtorv, Alexander Harald; Leitch, Calum; Bedringaas, Siv Lise; Gjertsen, Bjørn Tore; Bjørsvik, Hans-Rene (Peer reviewed; Journal article, 2015-08-06)

Computational chemistry has shown that backbone-alkylated imidazoles ought to be efficient ligands for transition metal catalysts with improved carbene-to-metal donation. In this work, such alkylated imidazoles were ...
FLT3-ITD mutations in acute myeloid leukaemia – molecular characteristics, distribution and numerical variation

Engen, Caroline; Hellesøy, Monica; Grob, Tim; Al Hinai, Adil; Brendehaug, Atle; Wergeland, Line; Bedringaas, Siv Lise; Hovland, Randi; Valk, Peter J. M.; Gjertsen, Bjørn T. (Journal article; Peer reviewed, 2021)

Recurrent somatic internal tandem duplications (ITD) in the FMS-like tyrosine kinase 3 (FLT3) gene characterise approximately one third of patients with acute myeloid leukaemia (AML), and FLT3-ITD mutation status guides ...