Browsing Bergen Open Research Archive by Author "Bergholtz, Helga"

Now showing items 1-2 of 2

Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns uncoupled from genomic drivers

Fougner, Christian; Bergholtz, Helga; Kuiper, Raoul; Norum, Jens Henrik; Sørlie, Therese (Peer reviewed; Journal article, 2019-07-31)

Background Claudin-low breast cancer is a molecular subtype associated with poor prognosis and without targeted treatment options. The claudin-low subtype is defined by certain biological characteristics, some of which may ...
A Longitudinal Study of the Association between Mammographic Density and Gene Expression in Normal Breast Tissue

Bergholtz, Helga; Lien, Tonje Gulbrandsen; Ursin, Giske; Holmen, Marit Muri; Helland, Åslaug; Sørlie, Therese; Haakensen, Vilde Drageset (Peer reviewed; Journal article, 2019-01-06)

High mammographic density (MD) is associated with a 4–6 times increase in breast cancer risk. For post-menopausal women,MD often decreases over time, but little is known about the underlying biological mechanisms. MD ...