• Apicomplexan actin polymerization depends on nucleation 

      Kumpula, Esa-Pekka; Pires, Isa; Lasiwa, Davki; Piirainen, Henni; Bergmann, Ulrich; Vahokoski, Juha; Kursula, Inari (Peer reviewed; Journal article, 2017-09-22)
      Filamentous actin is critical for apicomplexan motility and host cell invasion. Yet, parasite actin filaments are short and unstable. Their kinetic characterization has been hampered by the lack of robust quantitative ...
    • Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2 

      Ruskamo, Salla; Nieminen, Tuomo; Kristiansen, Cecilie Katrin; Vatne, Guro Helén; Baumann, Anne; Hallin, Erik Ingmar; Raasakka, Arne; Joensuu, Päivi; Bergmann, Ulrich; Vattulainen, Ilpo; Kursula, Petri (Peer reviewed; Journal article, 2017-07-26)
      Charcot-Marie-Tooth (CMT) disease is one of the most common inherited neuropathies. Recently, three CMT1-associated point mutations (I43N, T51P, and I52T) were discovered in the abundant peripheral myelin protein P2. These ...
    • Neuropathy-related mutations alter the membrane binding properties of the human myelin protein P0 cytoplasmic tail 

      Raasakka, Arne; Ruskamo, Salla; Barker, Robert; Krokengen, Oda Caspara; Vatne, Guro Helén; Kristiansen, Cecilie Katrin; Hallin, Erik Ingmar; Skoda, Maximilian W. A.; Bergmann, Ulrich; Wacklin-Knecht, Hanna; Jones, Nykola C; Hoffmann, Søren V; Kursula, Petri (Peer reviewed; Journal article, 2019-06-07)
      Schwann cells myelinate selected axons in the peripheral nervous system (PNS) and contribute to fast saltatory conduction via the formation of compact myelin, in which water is excluded from between tightly adhered lipid ...