• Agreement in reporting of asthma by parents or offspring - the RHINESSA generation study 

      Kuiper, Ingrid Nordeide; Svanes, Cecilie; Benediktsdóttir, Bryndís; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Dharmage, Shyamali C.; Holm, Mathias; Janson, Christer; Jõgi, Rain; Malinovschi, Andrei; Matheson, Melanie; Moratalla, Jesús Martínez; Gomez Real, Francisco; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Timm, Signe; Johannessen, Ane (Peer reviewed; Journal article, 2018-07-27)
      Background: Self-report questionnaires are commonly used in epidemiology, but may be susceptible to misclassification, especially if answers are given on behalf of others, e.g. children or parents. The aim was to determine ...
    • Ascaris exposure and its association with lung function, asthma, and DNA methylation in Northern Europe 

      Jögi, Nils Oskar; Kitaba, Negusse; Storaas, Torgeir; Schlünssen, Vivi; Triebner, Kai Philipp; Holloway, John W; Horsnell, William G.C.; Svanes, Cecilie; Bertelsen, Randi Jacobsen (Journal article; Peer reviewed, 2022)
      Background Ascaris infections, with a worldwide prevalence above 10%, can cause respiratory pathology. However, long-term effects on lung function in humans are largely unknown. Objective We investigated the associations ...
    • The Association of Gum Bleeding with Respiratory Health in a Population Based Study from Northern Europe 

      Gomez, Francisco; Barrionuevo, Laura Perez; Franklin, K.; Lindberg, E.; Bertelsen, Randi Jacobsen; Benediktsdottir, Bryndis; Forsberg, B; Gislason, T; Jøgi, Rain; Johannessen, Ane; Omenaas, Ernst; Saure, Eirunn Waatevik; Schlunssen, V.; Skorge, Trude Duelien; Toren, Kjell; Saavedra, A; Svanes, Øistein; Åstrøm, Anne Nordrehaug; Janson, Christer; Svanes, Cecilie (Peer reviewed; Journal article, 2016-01-25)
      Background: There is little knowledge about how oral and respiratory health is interrelated even though the mucosa of the oral cavity and airways constitutes a continuum and the exposures to these are partly similar. Aims: ...
    • Association of oral bacteria with oral hygiene habits and self-reported gingival bleeding 

      Bertelsen, Randi Jacobsen; Perez Barrionuevo, Antonio Manuel; Shigdel, Rajesh; Lie, Stein Atle; Lin, Huang; Real, Francisco Gomez; Ringel-Kulka, Tamar; Åstrøm, Anne-Kristine N; Svanes, Cecilie (Journal article; Peer reviewed, 2022)
      Aim To describe associations of gingival bacterial composition and diversity with self-reported gingival bleeding and oral hygiene habits in a Norwegian regional-based population. Materials and Methods We examined the ...
    • Associations of preconception exposure to air pollution and greenness with offspring asthma and hay fever 

      Kuiper, Ingrid Nordeide; Markevych, Iana; Accordini, Simone; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Christensen, Jesper Heile; Forsberg, Bertil; Halvorsen, Thomas; Heinrich, Joachim; Hertel, Ole; Hoek, Gerard; Holm, Mathias; de Hoogh, Kees; Janson, Christer; Malinovschi, Anderi; Marcon, Alessandro; Sigsgaard, Torben; Svanes, Cecilie; Johannessen, Ane (Journal article; Peer reviewed, 2020)
      We investigated if greenness and air pollution exposure in parents’ childhood affect offspring asthma and hay fever, and if effects were mediated through parental asthma, pregnancy greenness/pollution exposure, and offspring ...
    • Being overweight in childhood, puberty, or early adulthood: Changing asthma risk in the next generation? 

      Johannessen, Ane; Lønnebotn, Marianne; Calciano, Lucia; Benediktsdóttir, Bryndís; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Dharmage, Shyamali; Franklin, Karl A.; Gíslason, Þórarinn; Holm, Mathias; Janson, Christer; Jarvis, Deborah; Jõgi, Rain; Kim, Jeong-Lim; Kirkeleit, Jorunn; Lodge, Caroline; Malinovschi, Andrei; Martinez-Moratalla, Jesus; Nilsen, Roy Miodini; Pereira-Vega, Antonio; Gomez Real, Francisco; Schlünssen, Vivi; Accordini, Simone; Svanes, Cecilie (Peer reviewed; Journal article, 2020-03)
      Background Overweight status and asthma have increased during the last decades. Being overweight is a known risk factor for asthma, but it is not known whether it might also increase asthma risk in the next generation. ...
    • Cohort profile: the multigeneration Respiratory Health in Northern Europe, Spain and Australia (RHINESSA) cohort 

      Svanes, Cecilie; Johannessen, Ane; Bertelsen, Randi Jacobsen; Dharmage, Shyamali; Benediktsdottir, Bryndis; Bråbäck, Lennart; Gislason, Thorarinn; Holm, Mathias; Jögi, Oskar; Lodge, Caroline J; Malinovschi, Andrei; Martinez-Moratalla, Jesus; Oudin, Anna; Sánchez-Ramos, José Luis; Timm, Signe; Janson, Christer; Real, Francisco Gomez; Schlünssen, Vivi (Journal article; Peer reviewed, 2022)
      Purpose The Respiratory Health in Northern Europe, Spain and Australia (RHINESSA) cohort was established to (1) investigate how exposures before conception and in previous generations influence health and disease, ...
    • Cow Farmers’ Homes Host More Diverse Airborne Bacterial Communities Than Pig Farmers’ Homes and Suburban Homes 

      Abouelhana, Hesham Amin Mohamed; Šantl-Temkiv, Tina; Cramer, Christine; Vestergaard, Ditte V.; Holst, Gitte J.; Elholm, Grethe; Finster, Kai; Bertelsen, Randi Jacobsen; Schlünssen, Vivi; Sigsgaard, Torben; Marshall, Ian P. G. (Journal article; Peer reviewed, 2022)
      Living on a farm has been linked to a lower risk of immunoregulatory disorders, such as asthma, allergy, and inflammatory bowel disease. It is hypothesized that a decrease in the diversity and composition of indoor microbial ...
    • Epigenome-wide association of father's smoking with offspring DNA methylation: a hypothesis-generating study 

      Mørkve Knudsen, G.T.; Rezwan, FI; Johannessen, Ane; Skulstad, Svein Magne; Bertelsen, Randi Jacobsen; Gomez Real, Francisco; Krauss-Etschmann, Susanne; Patil, Viswanath; Jarvis, Deborah; Arshad, SH; Holloway, John W; Svanes, Cecilie (Peer reviewed; Journal article, 2019)
      Epidemiological studies suggest that father’s smoking might influence their future children’s health, but few studies have addressed whether paternal line effects might be related to altered DNA methylation patterns in the ...
    • The Exposome Approach in Allergies and Lung Diseases: Is It Time to Define a Preconception Exposome? 

      López Cervantes, Juan Pablo; Lønnebotn, Marianne; Jögi, Nils Oskar; Calciano, Lucia; Kuiper, Ingrid Nordeide; Darby, Matthew G; Dharmage, Shyamali Chandrika; Real, Francisco Gomez; Hammer, Barbara; Bertelsen, Randi Jacobsen; Johannessen, Ane; Würtz, Anne Mette Lund; Knudsen, Gerd Toril Mørkve; Koplin, Jennifer; Pape, Kathrine; Skulstad, Svein Magne; Timm, Signe; Tjalvin, Gro; Krauss-Etschmann, Susanne; Accordini, Simone; Schlünssen, Vivi; Kirkeleit, Jorunn; Svanes, Cecilie (Journal article; Peer reviewed, 2021)
      Emerging research suggests environmental exposures before conception may adversely affect allergies and lung diseases in future generations. Most studies are limited as they have focused on single exposures, not considering ...
    • Exposure to environmental phenols and parabens, and relation to body mass index, eczema and respiratory outcomes in the Norwegian RHINESSA study 

      Vindenes, Hilde Kristin; Svanes, Cecilie; Lygre, Stein Håkon Låstad; Real, Francisco Gomez; Ringel-Kulka, Tamar; Bertelsen, Randi Jacobsen (Journal article; Peer reviewed, 2021)
      Background Many phenols and parabens are applied in cosmetics, pharmaceuticals and food, to prevent growth of bacteria and fungi. Whether these chemicals affect inflammatory diseases like allergies and overweight is largely ...
    • Exposures during the prepuberty period and future offspring's health: evidence from human cohort studies 

      Svanes, Cecilie; Bertelsen, Randi Jacobsen; Accordini, Simone; Holloway, John W.; Juliusson, Pétur Benedikt; Boateng, Eistine; Krauss-Etchmann, Susanne; Schlünssen, Vivi; Real, Francisco Gomez; Skulstad, Svein Magne (Journal article; Peer reviewed, 2021)
      Emerging evidence suggests that exposures in prepuberty, particularly in fathers-to-be, may impact the phenotype of future offspring. Analyses of the RHINESSA cohort find that offspring of father’s exposed to tobacco smoking ...
    • Is atopic sensitization associated with indicators of early vascular ageing in adolescents? 

      Königstein, Karsten; Infanger, Denis; Bertelsen, Randi Jacobsen; Johannessen, Ane; Waje-Andreassen, Ulrike; Schmidt-Trucksäss, Arno; Svanes, Cecilie; Dratva, Julia (Peer reviewed; Journal article, 2019)
      Background: Chronic systemic inflammation accelerates early vascular ageing. Atopic sensitization and allergic diseases may involve increased inflammatory activity. This study aimed to assess whether atopic sensitization ...
    • Lifelong exposure to air pollution and greenness in relation to asthma, rhinitis and lung function in adulthood 

      Kuiper, Ingrid Nordeide; Svanes, Cecilie; Markevych, Iana; Accordini, Simone; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Christensen, Jesper Heile; Forsberg, Bertil; Halvorsen, Thomas; Heinrich, Joachim; Hertel, Ole; Hoek, Gerard; Holm, Mathias; De Hoogh, Kees; Janson, Christer; Malinovschi, Andrei; Marcon, Alessandro; Nilsen, Roy Miodini; Sigsgaard, Torben; Johannessen, Ane (Journal article; Peer reviewed, 2021)
      Objectives To investigate if air pollution and greenness exposure from birth till adulthood affects adult asthma, rhinitis and lung function. Methods: We analysed data from 3428 participants (mean age 28) in the RHINESSA ...
    • Lifelong exposure to residential greenspace and the premenstrual syndrome: A population-based study of Northern European women 

      Triebner, Kai Philipp; Markevych, Iana; Bertelsen, Randi Jacobsen; Skottvoll, Bente Sved; Hustad, Simon Steinar; Forsberg, Bertil; Franklin, Karl A; Holm, Mathias; Lindberg, Eva; Heinrich, Joachim; Real, Francisco Gomez; Dadvand, Payam (Journal article; Peer reviewed, 2022)
      Background: The premenstrual syndrome (PMS) causes clinically relevant psychological and physical symptoms in up to 20% of women of reproductive age. To date, no studies have investigated the relationship between PMS and ...
    • Maternal preconception occupational exposure to cleaning products and disinfectants and offspring asthma 

      Tjalvin, Gro; Svanes, Øistein; Igland, Jannicke; Bertelsen, Randi Jacobsen; Benediktsdóttir, Bryndís; Dharmage, Shyamali; Forsberg, Bertil; Holm, Mathias; Janson, Christer; Jögi, Nils Oskar; Johannessen, Ane; Malinovschi, Andrei; Pape, Kathrine; Real, Francisco Gomez; Sigsgaard, Torben; Torén, Kjell; Vindenes, Hilde Kristin; Zock, Jan-Paul; Schlünssen, Vivi; Svanes, Cecilie (Journal article; Peer reviewed, 2021)
      Background Emerging research suggests health effects in offspring after parental chemical exposures before conception. Many future mothers are exposed to potent chemicals at work, but potential offspring health effects ...
    • Menopause as a predictor of new-onset asthma 

      Triebner, Kai; Johannessen, Ane; Puggini, Luca; Benediktsdottir, Bryndis; Bertelsen, Randi Jacobsen; Bifulco, Ersilia; Dharmage, Shyamali C.; Franklin, Karl A.; Gislason, Þórarinn; Holm, Mathias; Jarvis, Deborah; Leynaert, Bénédicte; Lindberg, Eva; Macsali, Ferenc; Malinovschi, Andrej; Norbäck, Dan; Omenaas, Ernst; Rodriguez, Francisco J; Saure, Eirunn Waatevik; Schlünssen, Vivi; Sigsgaard, Torben; Skorge, Trude Duelien; Wieslander, Gunilla; Zemp, Elisabeth; Svanes, Cecilie; Hustad, Simon Steinar; Gomez Real, Francisco (Peer reviewed; Journal article, 2015-01)
      Background: There is limited and conflicting evidence on the effect of menopause on asthma. Objectives: We sought to study whether the incidence of asthma and respiratory symptoms differ by menopausal status in a longitudinal ...
    • Parents’ smoking onset before conception as related to body mass index and fat mass in adult offspring: Findings from the RHINESSA generation study 

      Knudsen, Gerd Toril Mørkve; Dharmage, Shyamali C.; Janson, Christer; Abramson, Michael J.; Benediktsdóttir, Bryndís; Malinovschi, Andrei; Skulstad, Svein Magne; Bertelsen, Randi Jacobsen; Real, Francisco Gomez; Schlünssen, Vivi; Jögi, Nils Oskar; Sánchez-Ramos, José Luis; Holm, Mathias; Garcia-Aymerich, Judith; Forsberg, Bertil; Svanes, Cecilie; Johannessen, Ane (Journal article; Peer reviewed, 2020)
      Emerging evidence suggests that parents’ preconception exposures may influence offspring health. We aimed to investigate maternal and paternal smoking onset in specific time windows in relation to offspring body mass index ...
    • Periodontal Health status and lung function in two Norwegian cohorts 

      Perez Barrionuevo, Antonio Manuel; Gomez Real, Francisco; Igland, Jannicke; Johannessen, Ane; Omenaas, Ernst; Franklin, Karl A.; Barrionuevo, Laura Perez; Åstrøm, Anne Nordrehaug; Svanes, Cecilie; Bertelsen, Randi Jacobsen (Peer reviewed; Journal article, 2018-01-19)
      Rationale and objectives: The oral cavity is united with the airways, and thus poor oral health may affect respiratory health. However, data on the interaction of periodontal and respiratory health is limited. We aimed to ...
    • Physical activity in pregnancy: a Norwegian-Swedish mother-child birth cohort study 

      Carlsen, Oda Cecilie; Gudmundsdóttir, Hrefna Katrín; Bains, Karen Eline Stensby; Bertelsen, Randi Jacobsen; Carlsen, Karin C. Lødrup; Carlsen, Kai-Håkon; Endre, Kim Magnus Advocaat; Granum, Berit; Haugen, Guttorm; Hedlin, Gunilla; Jonassen, Christine M; Kreyberg, Ina; Landrø, Linn Aina Ysland; Olsson, Caroline-Aleksi; Nordlund, Björn; Nordhagen, Live Solveig; Pehrson, Kristian; Saunders, Carina M.; Sjøborg, Katrine Dønvold; Skjerven, Håvard Ove; Staff, Anne Cathrine; Svanes, Cecilie; Söderhall, Cilla; Vettukattil, Riyas; Værnesbranden, Caren Magdalena Rydland; Wiik, Johanna; Rehbinder, Eva Maria (Journal article; Peer reviewed, 2021)
      BACKGROUND Physical activity during pregnancy is important for maternal and offspring health. Optimal conditions during pregnancy may help reduce the burden of noncommunicable diseases. National and international guidelines ...