Blar i Bergen Open Research Archive på forfatter "Bischof, Katharina"
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CD24-targeted fluorescence imaging in patient-derived xenograft models of high-grade serous ovarian carcinoma
Kleinmanns, Katrin; Bischof, Katharina; Anandan, Shamundeeswari; Popa, Mihaela Lucia; Akslen, Lars A.; Gjertsen, Bjørn Tore; Karlsen, Ida; Fosse, Vibeke Samuelsen; Bjørge, Line; Mc Cormack, Emmet (Journal article; Peer reviewed, 2020)Background The survival rate of patients with advanced high-grade serous ovarian carcinoma (HGSOC) remains disappointing. Clinically translatable orthotopic cell line xenograft models and patient-derived xenografts (PDXs) ... -
The HDACi panobinostat shows growth inhibition both in vitro and in a bioluminescent orthotopic surgical xenograft model of ovarian cancer
Helland, Øystein; Popa, Mihaela Lucia; Bischof, Katharina; Gjertsen, Bjørn Tore; McCormack, Emmet; Bjørge, Line (Peer reviewed; Journal article, 2016-06-28)Background: In most epithelial ovarian carcinomas (EOC), epigenetic changes are evident, and overexpression of histone deacetylases (HDACs) represents an important manifestation. In this study, we wanted to evaluate the ... -
Influence of p53 isoform expression on survival in high-grade serous ovarian cancers
Bischof, Katharina; Knappskog, Stian; Hjelle, Sigrun Margrethe; Stefansson, Ingunn; Woie, Kathrine; Salvesen, Helga; Gjertsen, Bjørn Tore; Bjørge, Line (Peer reviewed; Journal article, 2019-03-27)High-grade serous ovarian carcinoma (HGSOC) is characterised by alterations in the p53 pathway. The expression levels of p53 isoforms have been shown to be associated with patient survival in several cancers. This study ...