Browsing Bergen Open Research Archive by Author "Bjune, Jan-Inge"

Now showing items 1-5 of 5

    • COL6A3 expression in adipose tissue cells is associated with levels of the homeobox transcription factor PRRX1 

      Dankel, Simon N; Grytten, Elise; Bjune, Jan-Inge; Nielsen, Hans Jørgen; Dietrich, Arne; Blüher, Matthias; Sagen, Jørn V.; Mellgren, Gunnar (Journal article; Peer reviewed, 2020)
      Fibrillar collagen COL6α3 in adipose tissue has been associated with obesity, inflammation, insulin resistance and cancer. We here aimed to identify novel transcriptional regulators of COL6A3 expression. Based on a ...

    • Metabolic and Epigenetic Regulation by Estrogen in Adipocytes 

      Bjune, Jan-Inge; Strømland, Pouda Panahandeh; Jersin, Regine Åsen; Mellgren, Gunnar; Dankel, Simon N (Journal article; Peer reviewed, 2022-02-22)
      Sex hormones contribute to differences between males and females in body fat distribution and associated disease risk. Higher concentrations of estrogens are associated with a more gynoid body shape and with more fat storage ...

    • Perceived Health Status: Is Obesity Perceived as a Risk Factor and Disease? 

      Visscher, Tommy L.S.; Lakerveld, Jeroen; Olsen, Nanna; Küpers, Leanne; Ramalho, Sofia; Keaver, Laura; Brei, Christina; Bjune, Jan-Inge; Ezquerro, Silvia; Yumuk, Volkan (Peer reviewed; Journal article, 2017)
      One might expect that a perception of obesity being a risk factor and disease, contributes to effective obesity prevention and management strategies. However, obesity rates continue to increase worldwide. The question ...

    • Regulation of adipogenesis and fat storage by IRX3 and IRX5 

      Bjune, Jan-Inge (Doctoral thesis, 2020-04-24)
      Obesity is a highly prevalent disease underlying several chronic diseases including Type 2 diabetes (T2D) and cardiovascular diseases (CVDs). Thus, increasing levels of obesity is associated with a series of co-morbidities ...

    • Role of the Neutral Amino Acid Transporter SLC7A10 in Adipocyte Lipid Storage, Obesity and Insulin Resistance 

      Jersin, Regine Åsen; Tallapragada, Divya Sri Priyanka; Madsen, André; Skartveit, Linn; Fjære, Even; McCann, Adrian; Dyer, Laurence; Willems, Aron; Bjune, Jan-Inge; Bjune, Mona Synnøve; Våge, Villy; Nielsen, Hans Jørgen; Thorsen, Håvard Luong; Nedrebø, Bjørn Gunnar; Busch, Christian; Steen, Vidar M.; Blüher, Matthias; Jacobson, Peter; Svensson, Per-Arne; Fernø, Johan; Rydén, Mikael; Arner, Peter; Nygård, Ottar; Claussnitzer, Melina; Ellingsen, Ståle; Madsen, Lise; Sagen, Jørn V.; Mellgren, Gunnar; Dankel, Simon N (Journal article; Peer reviewed, 2021)
      Elucidation of mechanisms that govern lipid storage, oxidative stress, and insulin resistance may lead to improved therapeutic options for type 2 diabetes and other obesity-related diseases. Here, we find that adipose ...