Browsing Bergen Open Research Archive by Author "Blaser, Nello"

Now showing items 1-16 of 16

    • Binary time series classification with Bayesian convolutional neural networks when monitoring for marine gas discharges 

      Gundersen, Kristian; Alendal, Guttorm; Oleynik, Anna; Blaser, Nello (Journal article; Peer reviewed, 2020-06-19)
      The world’s oceans are under stress from climate change, acidification and other human activities, and the UN has declared 2021–2030 as the decade for marine science. To monitor the marine waters, with the purpose of ...

    • Candidate markers for stratification and classification in rheumatoid arthritis 

      Bader, Lucius; Gullaksen, Stein-Erik; Blaser, Nello; Brun, Morten; Bringeland, Gerd Haga; Sulen, Andre; Gjesdal, Clara Gram; Vedeler, Christian A.; Gavasso, Sonia (Peer reviewed; Journal article, 2019-07-05)
      Rheumatoid arthritis (RA) is a chronic autoimmune, inflammatory disease, characterized by synovitis in small- and medium-sized joints and, if not treated early and efficiently, joint damage, and destruction. RA is a ...

    • Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) caged at a capped waste disposal site in Kollevåg, Western Norway 

      Dale, Karina; Müller, Mette Bjørge; Tairova, Zhanna; Khan, Essa Ahsan; Hatlen, Kristin; Grung, Merete; Yadetie, Fekadu; Lille-Langøy, Roger; Blaser, Nello; Skaug, Hans J; Lyche, Jan Ludvig; Arukwe, Augustine; Hylland, Ketil; Karlsen, Odd André; Goksøyr, Anders (Peer reviewed; Journal article, 2019)
      The aim of this study was to assess whether fish in Kollevåg, a sheltered bay on the western coast of Norway, previously utilized as a waste disposal site, could be affected by environmental contaminants leaking from the ...

    • Early response evaluation by single cell signaling profiling in acute myeloid leukemia 

      Tislevoll, Benedicte Sjo; Hellesøy, Monica; Fagerholt, Oda Helen Eck; Gullaksen, Stein-Erik; Srivastava, Aashish; Birkeland, Even; Kleftogiannis, Dimitrios; Ayuda Duran, Pilar; Piechaczyk, Laure Isabelle; Tadele, Dagim Shiferaw; Skavland, Jørn; Panagiotis, Baliakas; Hovland, Randi; Andresen, Vibeke; Seternes, Ole Morten; Tvedt, Tor Henrik Anderson; Aghaeepour, Nima; Gavasso, Sonia; Porkka, Kimmo; Jonassen, Inge; Fløisand, Yngvar; Enserink, Jorrit; Blaser, Nello; Gjertsen, Bjørn Tore (Journal article; Peer reviewed, 2023)
      Aberrant pro-survival signaling is a hallmark of cancer cells, but the response to chemotherapy is poorly understood. In this study, we investigate the initial signaling response to standard induction chemotherapy in a ...

    • ETH-Tight Algorithms for Finding Surfaces in Simplicial Complexes of Bounded Treewidth 

      Black, Mitchell; Blaser, Nello; Nayyeri, Amir; Vågset, Erlend Raa (Journal article; Peer reviewed, 2022)
      Given a simplicial complex with n simplices, we consider the Connected Subsurface Recognition (c-SR) problem of finding a subcomplex that is homeomorphic to a given connected surface with a fixed boundary. We also study ...

    • GUBS: Graph-Based Unsupervised Brain Segmentation in MRI Images 

      Mayala, Simeon Sahani; Herdlevær, Ida Ajvazi; Haugsøen, Jonas Bull; Anandan, Shamundeeswari; Blaser, Nello; Gavasso, Sonia; Brun, Morten (Journal article; Peer reviewed, 2022)
      Brain segmentation in magnetic resonance imaging (MRI) images is the process of isolating the brain from non-brain tissues to simplify the further analysis, such as detecting pathology or calculating volumes. This paper ...

    • Integrative omics-analysis of lipid metabolism regulation by peroxisome proliferator-activated receptor a and b agonists in male Atlantic cod 

      Eide, Marta; Goksøyr, Anders; Yadetie, Fekadu; Gilabert, Alejandra; Bartosova, Zdenka; Frøysa, Håvard Guldbrandsen; Fallahi, Shirin; Zhang, Xiaokang; Blaser, Nello; Jonassen, Inge; Bruheim, Per; Alendal, Guttorm; Brun, Morten; Porte, Cinta; Karlsen, Odd André (Journal article; Peer reviewed, 2023-03-22)
      Lipid metabolism is essential in maintaining energy homeostasis in multicellular organisms. In vertebrates, the peroxisome proliferator-activated receptors (PPARs, NR1C) regulate the expression of many genes involved in ...

    • Optimal sensors placement for detecting CO2 discharges from unknown locations on the seafloor 

      Oleynik, Anna; García-Ibáñez, Maribel I.; Blaser, Nello; Omar, Abdirahman; Alendal, Guttorm (Journal article; Peer reviewed, 2020-04)
      Assurance monitoring of the marine environment is a required and intrinsic part of CO2 storage project. To reduce the costs related to the monitoring effort, the monitoring program must be designed with optimal use of ...

    • Optimization of receptor occupancy assays in mass cytometry: Standardization across channels with QSC beads 

      Bringeland, Gerd Haga; Bader, Lucius; Blaser, Nello; Budzinski, Lisa; Schulz, Axel R.; Mei, Henrik E.; Myhr, Kjell-Morten; Vedeler, Christian A.; Gavasso, Sonia (Peer reviewed; Journal article, 2019)
      Receptor occupancy, the ratio between amount of drug bound and amount of total receptor on single cells, is a biomarker for treatment response to therapeutic monoclonal antibodies. Receptor occupancy is traditionally ...

    • The parameterized complexity of finding minimum bounded chains 

      Blaser, Nello; Brun, Morten; Salbu, Lars Moberg; Vågset, Erlend Raa (Journal article; Peer reviewed, 2024)
      Finding the smallest d-chain with a specific (d − 1)-boundary in a simplicial complex is known as the Minimum Bounded Chain problem (MBCd). MBCd is NP-hard for all d ≥2. In this paper, we prove that it is also W[1]-hard ...

    • Relative Persistent Homology 

      Blaser, Nello; Brun, Morten (Journal article; Peer reviewed, 2020)
      The alpha complex efficiently computes persistent homology of a point cloud X in Euclidean space when the dimension d is low. Given a subset A of X, relative persistent homology can be computed as the persistent homology ...

    • Relative Persistent Homology 

      Blaser, Nello; Brun, Morten (Journal article; Peer reviewed, 2022)
      The alpha complex efficiently computes persistent homology of a point cloud X in Euclidean space when the dimension d is low. Given a subset A of X, relative Čech persistent homology can be computed as the persistent ...

    • Semi-conditional variational auto-encoder for flow reconstruction and uncertainty quantification from limited observations 

      Gundersen, Kristian; Oleynik, Anna; Blaser, Nello; Alendal, Guttorm (Journal article; Peer reviewed, 2021)
      We present a new data-driven model to reconstruct nonlinear flow from spatially sparse observations. The proposed model is a version of a Conditional Variational Auto-Encoder (CVAE), which allows for probabilistic ...

    • Sparse Dowker nerves 

      Brun, Morten; Blaser, Nello (Peer reviewed; Journal article, 2019-06-29)
      We propose sparse versions of filtered simplicial complexes used to compute persistent homology of point clouds and of networks. In particular, we extend the Sparse Čech Complex of Cavanna et al. (A geometric perspective ...

    • Sparse Nerves in Practice 

      Blaser, Nello; Brun, Morten (Peer reviewed; Journal article, 2019)
      Topological data analysis combines machine learning with methods from algebraic topology. Persistent homology, a method to characterize topological features occurring in data at multiple scales is of particular interest. ...

    • Wearing-off at the end of natalizumab dosing intervals is associated with low receptor occupancy 

      Bringeland, Gerd Haga; Blaser, Nello; Myhr, Kjell-Morten; Vedeler, Christian A.; Gavasso, Sonia (Journal article; Peer reviewed, 2020-02)
      Objective: We aimed to investigate whether wearing-off symptoms at the end of the natalizumab dosing interval were associated with clinical and demographic patient characteristics or natalizumab receptor occupancy (RO) on ...