Blar i Bergen Open Research Archive på forfatter "Bulla, Jan"

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    • Alterations in auditory brain stem response distinguish occasional and constant tinnitus 

      Edvall, Niklas K.; Mehraei, Golbarg; Claeson, Martin; Lazar, Andra; Bulla, Jan; Leineweber, Constanze; Uhlén, Inger; Canlon, Barbara; Cederroth, Christopher R. (Journal article; Peer reviewed, 2022)
      BACKGROUND. The heterogeneity of tinnitus is thought to underlie the lack of objective diagnostic measures. METHODS. Longitudinal data from 20,349 participants of the Swedish Longitudinal Occupational Survey of Health ...

    • Association between Hyperacusis and Tinnitus 

      Cederroth, Christopher R; Lugo, Alessandra; Edvall, Niklas K.; Lazar, Andra; Lopez-Escamez, Jose Antonio; Bulla, Jan; Uhlen, Inger; Hoare, Darek J.; Baguley, David M.; Canlon, Barbara; Gallus, Silvano (Journal article; Peer reviewed, 2020-07)
      Many individuals with tinnitus report experiencing hyperacusis (enhanced sensitivity to sounds). However, estimates of the association between hyperacusis and tinnitus is lacking. Here, we investigate this relationship in ...

    • Computational issues in parameter estimation for hidden Markov models with template model builder 

      Bacri, Timothee Raphael Ferdinand; Berentsen, Geir Drage; Bulla, Jan; Støve, Bård (Journal article; Peer reviewed, 2023)
      A popular way to estimate the parameters of a hidden Markov model (HMM) is direct numerical maximization (DNM) of the (log-)likelihood function. The advantages of employing the TMB [Kristensen K, Nielsen A, Berg C, et al. ...

    • Daily Contributors of Tinnitus Loudness and Distress: An Ecological Momentary Assessment Study 

      Simoes, Jorge; Bulla, Jan; Neff, Patrick; Pryss, Rüdiger; Marcrum, Steven C.; Langguth, Berthold; Schlee, Winfried (Journal article; Peer reviewed, 2022)
      Background: Tinnitus is a heterogeneous condition which may be associated with moderate to severe disability, but the reasons why only a subset of individuals is burdened by the condition are not fully clear. Ecological ...

    • Diurnal gait fluctuations in single- and dual- task conditions 

      Bessot, Nicolas; Polyte, Raphaël; Quesney, Marius; Bulla, Jan; Gauthier, Antoine (Journal article; Peer reviewed, 2020)
      Gait is one of the most basic movements, and walking activity accomplished in dual task conditions realistically represents daily life mobility. Much is known about diurnal variations of gait components such as muscle ...

    • The Effect of Environmental Stressors on Tinnitus: A Prospective Longitudinal Study on the Impact of the COVID-19 Pandemic 

      Schlee, Winfried; Hølleland, Sondre; Bulla, Jan; Simoes, Jorge; Neff, Patrick; Schoisswohl, Stefan; Woelflick, Stella; Schecklmann, Martin; Schiller, Axel; Staudinger, Susanne; Probst, Thomas; Langguth, Berthold (Journal article; Peer reviewed, 2020-08)
      Tinnitus, the perception of sound in the absence of a corresponding sound, and the distress caused by it, is rarely a static phenomenon. It rather fluctuates over time depending on endogenous and exogenous factors. The ...

    • Effects of complex neck therapy – kinesiotherapy and interspinal muscles massage – on tinnitus 

      Spencer, Shikha; Sereda, Magdalena; Marzena, Bielińska; Olszewski, Jurek; Adebusoye, Busola; Sobkiewicz, Adam; Bacri, Timothee Raphael Ferdinand; Bulla, Jan; Mielczarek, Marzena (Journal article, 2023)
      Introduction: Past studies have shown connections between the somatosensory system (the neck and temporomandibular joint region) and the auditory system. It is therefore likely that tinnitus patients might benefit from ...

    • The genetic vulnerability to cisplatin ototoxicity: a systematic review 

      Tserga, Evangelia; Nandwani, Tara; Edvall, Niklas K; Bulla, Jan; Patel, Poulam; Canlon, Barbara; Cederroth, Christopher R; Baguley, David M (Peer reviewed; Journal article, 2019-03-05)
      Ototoxicity is one of the major side-effects of platinum-based chemotherapy, in particular cisplatin (cis-diammine dichloroplatinum II). To our knowledge, no systematic review has previously provided a quantitative summary ...

    • A gentle tutorial on accelerated parameter and confidence interval estimation for hidden Markov models using Template Model Builder 

      Bacri, Timothee Raphael Ferdinand; Berentsen, Geir Drage; Bulla, Jan; Hølleland, Sondre Nedreås (Journal article; Peer reviewed, 2022)
      A very common way to estimate the parameters of a hidden Markov model (HMM) is the relatively straightforward computation of maximum likelihood (ML) estimates. For this task, most users rely on user-friendly implementation ...

    • Impact of temporomandibular joint complaints on tinnitus-related distress 

      Edvall, Niklas K; Gunan, Edis; Genitsaridi, Eleni; Lazar, Andra; Mehraei, Golbarg; Billing, Mattias; Tullberg, Marie; Bulla, Jan; Whitton, Jonathon; Canlon, Barbara; Hall, Deborah A; Cederroth, Christopher R (Peer reviewed; Journal article, 2019-08-22)
      There is increasing evidence of associations between the presence of temporomandibular joint (TMJ) disorders and tinnitus. It has been recently proposed that tinnitus patients with TMJ complaints could constitute a subtype, ...

    • Modelling clusters of corporate defaults: Regime-switching models significantly reduce the contagion source 

      Berentsen, Geir Drage; Bulla, Jan; Maruotti, Antonello; Støve, Bård (Journal article; Peer reviewed, 2022)
      In this paper, we report robust evidence that the process of corporate defaults is time-dependent and can be modelled by extending an autoregressive count time series model class via the introduction of regime-switching. ...

    • Polish Translation and Validation of the Tinnitus Handicap Inventory and the Tinnitus Functional Index 

      Wrzosek, Małgorzata; Eugeniusz, Szymiec; Wiesława, Klemens; Kotyło, Piotr; Schlee, Winfried; Modrzynska, Małgorzata; Agnieszka, Lang-Małecka; Anna, Preis; Bulla, Jan (Peer reviewed; Journal article, 2016-11-29)
      Objective: The need for validated measures enabling clinicians to classify tinnitus patients according to the severity of tinnitus and screen the progress of therapies in our country led us to translate into Polish and to ...

    • Relationship between headaches and tinnitus in a Swedish study 

      Lugo, Alessandra; Edvall, Niklas K.; Lazar, Andra; Mehraei, Golbarg; Lopez-Escamez, Jose Antonio; Bulla, Jan; Uhlen, Inger; Canlon, Barbara; Gallus, Silvano; Cederroth, Christopher R (Journal article; Peer reviewed, 2020-05)
      The heterogeneity of tinnitus is likely accounting for the lack of effective treatment approaches. Headaches have been related to tinnitus, yet little is known on how headaches impact tinnitus. We use cross-sectional data ...

    • Screening for Circulating Inflammatory Proteins Does Not Reveal Plasma Biomarkers of Constant Tinnitus 

      Cederroth, Christopher R.; Hong, Mun-Gwan; Freydin, Maxim B.; Edvall, Niklas K.; Trpchevska, Natalia; Jarach, Carlotta; Schlee, Winfried; Schwenk, Jochen M.; Lopez-Escamez, Jose-Antonio; Gallus, Silvano; Canlon, Barbara; Bulla, Jan; Williams, Frances M. K. (Journal article; Peer reviewed, 2023)
      Background and Objective Tinnitus would benefit from an objective biomarker. The goal of this study is to identify plasma biomarkers of constant and chronic tinnitus among selected circulating inflammatory proteins. ...

    • Sexual dimorphism in the familial aggregation of tinnitus 

      Trpchevska, Natalia; Bulla, Jan; Prada Hellberg, Matilda; Edvall, Niklas K.; Lazar, Andra; Mehraei, Golbarg; Uhlen, Inger; Schlee, Winfried; Canlon, Barbara; Gallus, Silvano; Lopez-Escamez, Jose Antonio; Cederroth, Christopher R (Journal article; Peer reviewed, 2020-11)
      Twin and adoption studies point towards a genetic contribution to tinnitus; however, how the genetic risk applies to different forms of tinnitus is poorly understood. Here, we perform a familial aggregation study and ...

    • Tinnitus Is Marginally Associated with Body Mass Index, Heart Rate and Arterial Blood Pressure: Results from a Large Clinical Sample 

      Langguth, Berthold; Bulla, Jan; Fischer, Beate; Baurecht, Hansjoerg; Schecklmann, Martin; Marcrum, Steven C.; Vielsmeier, Veronika (Journal article; Peer reviewed, 2023)
      Introduction: This study aimed to explore whether body mass index (BMI), systolic blood pressure (RR syst), diastolic blood pressure (RR diast) or heart rate (HR) are associated with tinnitus status and/or severity. Methods: ...

    • Toward personalized tinnitus treatment: An exploratory study based on internet crowdsensing 

      Simoes, Jorge; Neff, Patrick; Schoisswohl, Stefan; Bulla, Jan; Schecklmann, Martin; Harrison, Steve; Vesala, Markku; Langguth, Berthold; Schlee, Winfried (Peer reviewed; Journal article, 2019-06-25)
      Introduction: Chronic tinnitus is a condition estimated to affect 10–15% of the population. No treatment has shown efficacy in randomized clinical trials to reliably and effectively suppress the phantom perceptions, and ...

    • Using coding and non-coding rare variants to target candidate genes in patients with severe tinnitus 

      Gallego-Martinez, Alvaro; Escalera-Balsera, Alba; Trpchevska, Natalia; Robles-Bolivar, Paula; Roman-Naranjo, Pablo; Frejo, Lidia; Perez-Carpena, Patricia; Bulla, Jan; Gallus, Silvano; Canlon, Barbara; Cederroth, Christopher R.; Lopez-Escamez, Jose A. (Journal article; Peer reviewed, 2022)
      Tinnitus is the phantom percept of an internal non-verbal set of noises and tones. It is reported by 15% of the population and it is usually associated with hearing and/or brain disorders. The role of structural variants ...