Blar i Bergen Open Research Archive på forfatter "Burger, Bram"
-
Analyzing the Structure of Pathways and Its Influence on the Interpretation of Biomedical Proteomics Data Sets
Burger, Bram; Hernández Sánchez, Luis Francisco; Lereim, Ragnhild Reehorst; Barsnes, Harald; Vaudel, Marc (Peer reviewed; Journal article, 2018)Biochemical pathways are commonly used as a reference to conduct functional analysis on biomedical omics data sets, where experimental results are mapped to knowledgebases comprising known molecular interactions collected ... -
Detecting single amino acids and small peptides by combining isobaric tags and peptidomics
Burger, Bram; Lereim, Ragnhild Reehorst; Berven, Frode; Barsnes, Harald (Peer reviewed; Journal article, 2019)Single amino acids and small endogenous peptides play important roles in maintaining a properly functioning organism. These molecules are however currently only routinely identified in targeted approaches. In a small ... -
PathwayMatcher: proteoform-centric network construction enables fine-granularity multi-omics pathway mapping
Hernández Sánchez, Luis Francisco; Burger, Bram; Horro Marcos, Carlos; Fabregat, Antonio; Johansson, Stefan; Njølstad, Pål Rasmus; Barsnes, Harald; Hermjakob, Henning; Vaudel, Marc (Peer reviewed; Journal article, 2019-07-30)Background Mapping biomedical data to functional knowledge is an essential task in bioinformatics and can be achieved by querying identifiers (e.g., gene sets) in pathway knowledge bases. However, the isoform and ... -
Statistical considerations for the design and interpretation of proteomics experiments
Burger, Bram (Doctoral thesis, 2021-06-10)The methods to study proteins are continuously improving, making it possible to identify and study increasingly more proteins. It is important to keep studying and improving the way experiments are designed, performed, and ...