• The architecture of cell differentiation in choanoflagellates and sponge choanocytes 

      Laundon, Davis; Larson, Ben T; McDonald, Kent; King, Nicole; Burkhardt, Pawel (Journal article; Peer reviewed, 2019-04-12)
      Although collar cells are conserved across animals and their closest relatives, the choanoflagellates, little is known about their ancestry, their subcellular architecture, or how they differentiate. The choanoflagellate ...
    • Choanoflagellates and the ancestry of neurosecretory vesicles 

      Göhde, Ronja Alica Angelika; Naumann, Benjamin; Laundon, Davis; Imig, Cordelia; McDonald, Kent; Cooper, Benjamin H.; Varoqueaux, Frédérique; Fasshauer, Dirk; Burkhardt, Pawel (Journal article; Peer reviewed, 2021)
      Neurosecretory vesicles are highly specialized trafficking organelles that store neurotransmitters that are released at presynaptic nerve endings and are, therefore, important for animal cell–cell signalling. Despite ...
    • Exciting times to study the identity and evolution of cell types 

      Sachkova, Maria; Burkhardt, Pawel (Journal article, 2019)
      The EMBO/EMBL Symposium on ‘The Identity and Evolution of Cell Types’ took place in Heidelberg, Germany, on 15-19 May 2019. The symposium, which brought together a diverse group of speakers addressing a wide range of ...
    • Histone demethylase Lsd1 is required for the differentiation of neural cells in Nematostella vectensis 

      Gahan, James Michael; Kouzel, Ivan; Ormevik Jansen, Kamilla; Burkhardt, Pawel; Rentzsch, Fabian (Journal article; Peer reviewed, 2022)
      Chromatin regulation is a key process in development but its contribution to the evolution of animals is largely unexplored. Chromatin is regulated by a diverse set of proteins, which themselves are tightly regulated in a ...
    • The premetazoan ancestry of the synaptic toolkit and appearance of first neurons 

      Colgren, Jeffrey John; Burkhardt, Pawel (Journal article; Peer reviewed, 2022)
      Neurons, especially when coupled with muscles, allow animals to interact with and navigate through their environment in ways unique to life on earth. Found in all major animal lineages except sponges and placozoans, nervous ...