Blar i Bergen Open Research Archive på forfatter "Castilho, Aurea"
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AMPA receptors at ribbon synapses in the mammalian retina: kinetic models and molecular identity
Hartveit, Espen; Zandt, Bas-Jan; Madsen, Eirik; Castilho, Aurea; Mørkve, Svein Harald; Veruki, Margaret Lin (Peer reviewed; Journal article, 2017)In chemical synapses, neurotransmitter molecules released from presynaptic vesicles activate populations of postsynaptic receptors that vary in functional properties depending on their subunit composition. Differential ... -
Diabetic hyperglycemia reduces Ca2+ permeability of extrasynaptic AMPA receptors in AII amacrine cells
Castilho, Aurea; Madsen, Eirik; Ambrósio, António F.; Veruki, Margaret Lin; Hartveit, Espen (Peer reviewed; Journal article, 2015-09)There is increasing evidence that diabetic retinopathy is a primary neuropathological disorder that precedes the microvascular pathology associated with later stages of the disease. Recently, we found evidence for altered ... -
Disruption of a neural microcircuit in the rod pathway of the mammalian retina by diabetes mellitus
Castilho, Aurea; Ambrósio, António F.; Hartveit, Espen; Veruki, Margaret Lin (Peer reviewed; Journal article, 2015-04)Diabetes leads to dysfunction of the neural retina before and independent of classical microvascular diabetic retinopathy, but previous studies have failed to demonstrate which neurons and circuits are affected at the ... -
Extrasynaptic NMDA receptors on rod pathway amacrine cells: molecular composition, activation, and signaling
Veruki, Margaret Lin; Zhou, Yifan; Castilho, Aurea; Morgans, Catherine W.; Hartveit, Espen (Peer reviewed; Journal article, 2019)In the rod pathway of the mammalian retina, axon terminals of glutamatergic rod bipolar cells are presynaptic to AII and A17 amacrine cells in the inner plexiform layer. Recent evidence suggests that both amacrines express ...