• Dynamics of Plasma and Urinary Extracellular DNA in Acute Kidney Injury 

      Jančuška, Alexander; Potočárová, Alena; Kovalčíková, Alexandra Gaál; Podracká, L’Udmila; Babickova, Janka; Celec, Peter; Tóthová, L’Ubomíra (Journal article; Peer reviewed, 2022)
      Early and reliable markers of acute kidney injury (AKI) are essential. One such candidate marker of tissue damage is extracellular DNA (ecDNA). The aim of our present study is to describe the unknown dynamics of ecDNA in ...
    • The Effect of Melatonin on Periodontitis 

      Konečná, Barbora; Chobodová, Paulína; Janko, Jakub; Baňasová, Lenka; Babickova, Janka; Celec, Peter; Tóthová, L’Ubomíra (Journal article; Peer reviewed, 2021)
      Background: Periodontitis is a chronic disease with a complex etiology that includes bacterial colonization, excessive inflammation, and oxidative stress. The hormone melatonin has antioxidant properties and might contribute ...
    • Extracellular DNA concentrations in various aetiologies of acute kidney injury 

      Gaál Kovalčíková, Alexandra; Janovičová, Ľubica; Hodosy, Július; Babickova, Janka; Vavrincová-Yaghi, Diana; Vavrinec, Peter; Boor, Peter; Podracká, Ľudmila; Šebeková, Katarína; Celec, Peter; Tóthová, Ľubomíra (Journal article; Peer reviewed, 2022)
      Extracellular DNA (ecDNA) in plasma is a non-specific biomarker of tissue damage. Urinary ecDNA, especially of mitochondrial origin, is a potential non-invasive biomarker of kidney damage. Despite prominent tissue damage, ...
    • Oxidative Stress in Animal Models of Acute and Chronic Renal Failure 

      Gyuraszova, Marianna; Kovalcikova, Alexandra Gaal; Renczes, Emese; Kmetova, Katarina; Celec, Peter; Babickova, Janka; Tothova, Lubomira (Peer reviewed; Journal article, 2019-02-11)
      Introduction. Kidney disease is a worldwide health and economic burden, with rising prevalence. The search for biomarkers for earlier and more effective disease screening and monitoring is needed. Oxidative stress has been ...
    • Plasma Concentrations of Extracellular DNA in Acute Kidney Injury 

      Homolová, Jordanka; Janovičová, L'ubica; Konečná, Barbora; Vlková, Barbora; Celec, Peter; Tóthová, L'ubomíra; Babickova, Janka (Journal article; Peer reviewed, 2020)
      Current diagnostic methods of acute kidney injury (AKI) have limited sensitivity and specificity. Tissue injury has been linked to an increase in the concentrations of extracellular DNA (ecDNA) in plasma. A rapid turnover ...