• Auto-Adhesion Potential of Extraocular Aqp0 during Teleost Development 

      Chauvigné, Francois; Fjelldal, Per Gunnar; Cerdà, Joan; Finn, Roderick Nigel (Peer reviewed; Journal article, 2016-05-06)
      AQP0 water channels are the most abundant proteins expressed in the mammalian lens fiber membranes where they are essential for lens development and transparency. Unlike other aquaporin paralogs, mammalian AQP0 has a low ...
    • Insect glycerol transporters evolved by functional co-option and gene replacement 

      Finn, Roderick Nigel; Chauvigné, Francois; Stavang, Jon Anders; Belles, Xavier; Cerdà, Joan (Peer reviewed; Journal article, 2015-07-17)
      Transmembrane glycerol transport is typically facilitated by aquaglyceroporins in Prokaryota and Eukaryota. In holometabolan insects however, aquaglyceroporins are absent, yet several species possess polyol permeable ...
    • The lineage-specific evolution of aquaporin gene clusters facilitated tetrapod terrestrial adaptation 

      Finn, Roderick Nigel; Chauvigné, Francois; Hlidberg, Jón Baldur; Cutler, Christopher P.; Cerdà, Joan (Peer reviewed; Journal article, 2014-11-26)
      A major physiological barrier for aquatic organisms adapting to terrestrial life is dessication in the aerial environment. This barrier was nevertheless overcome by the Devonian ancestors of extant Tetrapoda, but the origin ...
    • The pH sensitivity of Aqp0 channels in tetraploid and diploid teleosts 

      Chauvigné, Francois; Zapater, Cinta; Stavang, Jon Anders; Taranger, Geir Lasse; Cerdà, Joan; Finn, Roderick Nigel (Peer reviewed; Journal article, 2015)
      Water homeostasis and the structural integrity of the vertebrate lens is partially mediated by AQP0 channels. Emerging evidence indicates that external pH may be involved in channel gating. Here we show that a tetraploid ...
    • Phylogenomic and functional analyses of salmon lice aquaporins uncover the molecular diversity of the superfamily in Arthropoda 

      Stavang, Jon Anders; Chauvigné, Francois; Kongshaug, Heidi; Cerdà, Joan; Nilsen, Frank; Finn, Roderick Nigel (Peer reviewed; Journal article, 2015-08-19)
      Background An emerging field in biomedical research is focusing on the roles of aquaporin water channels in parasites that cause debilitating or lethal diseases to their vertebrate hosts. The primary vectorial agents are ...
    • A transcriptomic analysis of diploid and triploid Atlantic salmon lenses with and without cataracts 

      Olsvik, Pål Asgeir; Finn, Roderick Nigel; Remø, Sofie C.; Fjelldal, Per Gunnar; Chauvigné, Francois; Glover, Kevin; Hansen, Tom Johnny; Waagbø, Rune (Journal article; Peer reviewed, 2020)
      To avoid negative environmental impacts of escapees and potential inter-breeding with wild populations, the Atlantic salmon farming industry has and continues to extensively test triploid fish that are sterile. However, ...
    • Unravelling the Complex Duplication History of Deuterostome Glycerol Transporters 

      Yilmaz, Ozlem; Chauvigné, Francois; Ferré, Alba; Nilsen, Frank; Fjelldal, Per Gunnar; Cerdà, Joan; Finn, Roderick Nigel (Journal article; Peer reviewed, 2020)
      Transmembrane glycerol transport is an ancient biophysical property that evolved in selected subfamilies of water channel (aquaporin) proteins. Here, we conducted broad level genome (>550) and transcriptome (>300) analyses ...
    • The vertebrate Aqp14 water channel is a neuropeptide-regulated polytransporter 

      Chauvigné, Francois; Yilmaz, Ozlem; Ferré, Alba; Fjelldal, Per Gunnar; Finn, Roderick Nigel; Cerdà, Joan (Peer reviewed; Journal article, 2019-12-11)
      Water channels (aquaporins) were originally discovered in mammals with fourteen subfamilies now identified (AQP0-13). Here we show that a functional Aqp14 subfamily phylogenetically related to AQP4-type channels exists in ...