Browsing Bergen Open Research Archive by Author "Chwiszczuk, Luiza"
Now showing items 1-6 of 6
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The ANeED study – ambroxol in new and early dementia with Lewy bodies (DLB): protocol for a phase IIa multicentre, randomised, double-blinded and placebo-controlled trial
Chwiszczuk, Luiza; Breitve, Monica Haraldseid; Kirsebom, Bjørn-Eivind; Selnes, Per; Fløvig, John Christian Jøraholmen; Knapskog, Anne Brita; Skogseth, Ragnhild Eide; Hubbers, Jessica; Holst-Larsen, Elin; Rongve, Arvid (Journal article; Peer reviewed, 2023-05-26)Background: Currently, there are no disease-modifying pharmacological treatment options for dementia with Lewy bodies (DLB). The hallmark of DLB is pathological alpha-synuclein (aS) deposition. There are growing amounts ... -
Cerebrospinal fluid neurofilament light chain mediates age-associated lower learning and memory in healthy adults
Hemminghyth, Mathilde Suhr; Chwiszczuk, Luiza; Breitve, Monica Haraldseid; Gisladottir, Berglind; Grøntvedt, Gøril Rolfseng; Nakling, Arne Exner; Rongve, Arvid; Fladby, Tormod; Kirsebom, Bjørn-Eivind Seljelid (Journal article; Peer reviewed, 2023)Multiple cognitive domains, including learning, memory, and psychomotor speed, show significant reductions with age. Likewise, several cerebrospinal fluid (CSF) neurodegenerative biomarkers, including total tau (t-tau, a ... -
The Cognitive Profile of Mild Cognitive Impairment Due to Dementia With Lewy Bodies—An Updated Review
Hemminghyth, Mathilde Suhr; Chwiszczuk, Luiza; Rongve, Arvid; Breitve, Monica Haraldseid (Journal article; Peer reviewed, 2020)Objective: Dementia with Lewy Bodies (DLB) is the second most common type of neurodegenerative dementia. Yet, the domain-specific cognitive impairment of the mild cognitive impairment (MCI) phase of this disease (DLB-MCI) ... -
Demens med Lewylegemer: søvn, kognisjon og nevropatologi
Chwiszczuk, Luiza (Doctoral thesis, 2019-01-17)Background Sleep disorders are frequent in patients with dementia. Sleep disturbances can negatively influence the disease burden of dementia and accelerate the rate of cognitive decline. It is hypothesized that sleep ... -
A Longitudinal Study of Neurocognition in Dementia with Lewy Bodies Compared to Alzheimer`s Disease
Breitve, Monica Haraldseid; Chwiszczuk, Luiza; Hynninen, Kia Minna; Brønnick, Kolbjørn Selvåg; Auestad, Bjørn Henrik; Aarsland, Dag; Rongve, Arvid (Peer reviewed; Journal article, 2018-03-06)Introduction: There are relatively few longitudinal studies on the differences in cognitive decline between Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB), and the majority of existing studies have ... -
REM sleep behavior disorder is not associated with a more rapid cognitive decline in mild dementia
Chwiszczuk, Luiza; Breitve, Monica Haraldseid; Brønnick, Kolbjørn Selvåg; Gjerstad, Michaela D; Hynninen, Kia Minna; Aarsland, Dag; Rongve, Arvid (Peer reviewed; Journal article, 2017-08-07)Objectives: REM sleep behavior disorder (RBD) is associated with cognitive dysfunctions and is a risk factor for development of mild cognitive impairment and dementia. However, it is unknown whether RBD is associated with ...