• The effect of blood protein adsorption on cellular uptake of anatase TiO2 nanoparticles 

      Allouni, Zouhir Ekeland; Gjerdet, Nils Roar; Cimpan, Mihaela Roxana; Høl, Paul Johan (Peer reviewed; Journal article, 2015-01-19)
      Protein adsorption onto nanoparticles (NPs) in biological fluids has emerged as an important factor when testing biological responses to NPs, as this may influence both uptake and subsequent toxicity. The aim of the present ...
    • High throughput toxicity screening and intracellular detection of nanomaterials 

      Collins, Andrew Richard; Balasubramanyam, Annangi; Rubio, Laura; Marcos, Ricard; Dorn, Marco; Merker, Carolin; Estrela-Lopis, Irina; Cimpan, Mihaela Roxana; Ibrahim, Mohamed; Cimpan, Emil; Ostermann, Melanie; Sauter, Alexander; El Yamani, Naouale; Shaposhnikov, Sergey; Chevillard, Sylvie; Paget, Vincent; Grall, Romain; Delic, Jozo; Goñi- de-Cerio, Felipe; Suarez-Merino, Blanca; Fessard, Valérie; Hogeveen, Kevin N; Fjellsbø, Lise Maria; Runden Pran, Elise; Brzicova, Tana; Topinka, Jan; João Silva, Maria; Leite, PE; Ribeiro, AR; Granjeiro, JM; Grafström, Roland; Prina-Mello, Adriele; Dusinska, Maria (Peer reviewed; Journal article, 2017-01)
      With the growing numbers of nanomaterials (NMs), there is a great demand for rapid and reliable ways of testing NM safety—preferably using in vitro approaches, to avoid the ethical dilemmas associated with animal research. ...
    • Knowledge about nanotechnology and intention to use nanomaterials: a comparative study among dental students in Norway and Romania 

      Xenaki, Victoria; Marthinussen, Mihaela Cudia; Costea, Daniela Elena; Didilescu, Andrea; Susin, Cristiano; Cimpan, Mihaela Roxana; Åstrøm, Anne Nordrehaug (Peer reviewed; Journal article, 2020)
      Background: The introduction of innovative nanotechnologies in medicine and dentistry may initiate a need for curriculum revision at the universities. The aim of this study was to assess dental students’ knowledge and ...
    • Label-free impedance flow cytometry for nanotoxicity screening 

      Ostermann, Melanie; Sauter, Alexander; Xue, Ying; Birkeland, Eivind Salmorin; Schoelermann, Julia; Holst, Bodil; Cimpan, Mihaela Roxana (Peer reviewed; Journal article, 2020)
      The development of reliable and cost-efficient methods to assess the toxicity of nanomaterials (NMs) is critical for the proper identification of their impact on human health and for ensuring a safe progress of nanotechnology. ...
    • Label-free monitoring of uptake and toxicity of endoprosthetic wear particles in human cell cultures 

      Jonitz-Heincke, Anika; Tillmann, Jenny; Ostermann, Melanie; Springer, Armin; Bader, Rainer; Høl, Paul Johan; Cimpan, Mihaela Roxana (Peer reviewed; Journal article, 2018)
      The evaluation of the biological effects of endoprosthetic wear particles on cells in vitro relies on a variety of test assays. However, most of these methods are susceptible to particle-induced interferences; therefore, ...
    • Microfluidics for studying metastatic patterns of lung cancer 

      Ruzycka, Monika; Cimpan, Mihaela Roxana; Rios Mondragon, Ivan; Grudzinski, Ireneusz (Peer reviewed; Journal article, 2019-05-27)
      The incidence of lung cancer continues to rise worldwide. Because the aggressive metastasis of lung cancer cells is the major drawback of successful therapies, the crucial challenge of modern nanomedicine is to develop ...
    • Nano-TiO2 penetration of oral mucosa: in vitro analysis using 3D organotypic human buccal mucosa models 

      Konstantinova, Victoria; Ibrahim, Mohamed; Lie, Stein Atle; Birkeland Salmorin, Eivind; Neppelberg, Evelyn; Marthinussen Cuida, Mihaela; Costea, Daniela Elena; Cimpan, Mihaela Roxana (Peer reviewed; Journal article, 2016)
      BACKGROUND: Oral cavity is a doorway for a variety of products containing titanium dioxide (TiO2) nanoparticles (NPs) (nano-TiO2) such as food additives, oral healthcare products and dental materials. Their potential to ...